Southern Mississippi will play 18 home games.
Southern Mississippi is first in action on
Fri, Nov 12th, 2010 and conclude their 32-game regular season on Thu, Mar 10th, 2011. This schedule features every game including the date, time, and location plus updated scores and pitcher information.
| DATE | OPPONENT | TIME (ET) | Location | Result |
| Fri, Nov 12th, 2010 | at South_Florida | 07:30 PM | USF Sun Dome | W (60 - 53) |
| Wed, Nov 17th, 2010 | South_Alabama | 08:00 PM | Reed Green Coliseum | W (93 - 58) |
| Mon, Nov 22nd, 2010 | McNeese_State | 08:00 PM | Reed Green Coliseum | W (75 - 60) |
| Sat, Nov 27th, 2010 | Spring_Hill | 08:30 PM | Reed Green Coliseum | W (94 - 41) |
| Wed, Dec 1st, 2010 | Alcorn_State | 08:00 PM | Reed Green Coliseum | W (100 - 71) |
| Sat, Dec 4th, 2010 | at Ole_Miss | 08:00 PM | C.M. Tad Smith Coliseum | L (86 - 81) |
| Sat, Dec 11th, 2010 | at CS-Monterey_Bay | 05:00 PM | Otter Sports Center | W (86 - 61) |
| Sun, Dec 12th, 2010 | at California | 05:00 PM | Haas Pavilion | W (80 - 78) |
| Wed, Dec 22nd, 2010 | East_Tenn_St | 02:30 PM | Poliforum Benito Juarez - Canc | W (64 - 60) |
| Thu, Dec 23rd, 2010 | Saint_Louis | 02:30 PM | Poliforum Benito Juarez - Canc | W (74 - 67) |
| Fri, Dec 24th, 2010 | at Colorado_State | 09:30 PM | Poliforum Benito Juarez - Canc | L (63 - 58) |
| Wed, Dec 29th, 2010 | Miss_Valley_St | 08:00 PM | Reed Green Coliseum | W (91 - 46) |
| Thu, Dec 30th, 2010 | Savannah_State | 08:00 PM | Reed Green Coliseum - Hattiesb | W (64 - 54) |
| Wed, Jan 5th, 2011 | Houston | 09:00 PM | Reed Green Coliseum | W (85 - 73) |
| Sat, Jan 8th, 2011 | at Marshall | 07:00 PM | Cam Henderson Center | L (95 - 65) |
| Wed, Jan 12th, 2011 | at Rice | 08:00 PM | Tudor Fieldhouse | W (81 - 78) |
| Sat, Jan 15th, 2011 | U-C-F | 05:00 PM | Reed Green Coliseum | W (86 - 69) |
| Wed, Jan 19th, 2011 | Memphis | 07:00 PM | Reed Green Coliseum | L (76 - 75) |
| Sat, Jan 22nd, 2011 | at S-M-U | 03:00 PM | Moody Coliseum | L (79 - 65) |
| Wed, Jan 26th, 2011 | at East_Carolina | 07:00 PM | Williams Arena at Minges Colis | W (84 - 77) |
| Sat, Jan 29th, 2011 | Tulane | 05:00 PM | Reed Green Coliseum | W (67 - 54) |
| Wed, Feb 2nd, 2011 | at U-A-B | 08:00 PM | Bartow Arena | W (75 - 71) |
| Sat, Feb 5th, 2011 | Marshall | 06:00 PM | Reed Green Coliseum | W (67 - 60) |
| Sat, Feb 12th, 2011 | at Memphis | 06:00 PM | FedExForum | L (67 - 61) |
| Wed, Feb 16th, 2011 | Texas-El_Paso | 08:00 PM | Reed Green Coliseum | W (64 - 51) |
| Sat, Feb 19th, 2011 | East_Carolina | 05:00 PM | Reed Green Coliseum | W (72 - 55) |
| Tue, Feb 22nd, 2011 | Loyola-NO | 08:00 PM | Reed Green Coliseum | W (78 - 67) |
| Sat, Feb 26th, 2011 | at U-C-F | 07:00 PM | UCF Arena | L (65 - 64) |
| Wed, Mar 2nd, 2011 | U-A-B | 07:00 PM | Reed Green Coliseum | L (67 - 66) |
| Sat, Mar 5th, 2011 | at Tulsa | 08:00 PM | Reynolds Center | L (78 - 70) |
| Wed, Mar 9th, 2011 | Tulane | 03:30 PM | Don Haskins Center - El Paso, | W (63 - 47) |
| Thu, Mar 10th, 2011 | at Memphis | 04:10 PM | Don Haskins Center - El Paso, | L (66 - 63) |
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