Chicago Cubs vs San Francisco Giants Prediction, 8/26/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs San Francisco Giants

Date: Tuesday, August 26, 2025

Location: Oracle Park in San Francisco, CA

TV: NBC Bay Area

Odds/Point Spread: Chicago (-160) San Francisco (+132)

Oracle Park is where the San Francisco Giants (63-68) will attempt to beat the Chicago Cubs (76-55) on Tuesday. The odds on this game have the Cubs at -160 and the Giants are coming in at +132. The total is set at 9. The men taking the mound will be Matthew Boyd and Justin Verlander.

As a team, the Chicago Cubs are recording 5.0 runs per contest, which has them sitting at 5th in the league. They have accumulated 648 runs while holding a team on-base percentage of .319. The Cubs have tallied 216 two-baggers as a team and have smacked 178 balls out of the stadium. They have 632 runs batted in and 1,112 hits for the season, and their team batting average comes in at .249. Chicago has a slugging percentage of .428 and have struck out 1,014 times, while drawing a walk on 444 occasions.

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The Cubs have an ERA of 3.76 so far this year (8th in baseball), and the staff has struck out 1,002 batters. Cubs pitchers have surrendered 159 home runs in addition to 522 total runs (6th in the league). Their pitching staff has walked 340 opposing players and their FIP sits at 4.15 as a unit for the year. Chicago has allowed 1,050 base knocks (8.1 per 9 innings) and also 486 earned runs. They have accrued a K/BB ratio of 2.95 and their pitching staff has recorded a WHIP of 1.19.

Cubs pitchers have entered the game with runners on base 86 times in addition to having 127 appearances in high leverage situations. The relief pitchers have notched 88 holds for the year (4th in the league). The Cubs relievers have accumulated a save rate of 70.0% and have entered the game in 141 save situations. They have earned 35 saves for the year and have missed out on 15 of their 50 save opportunities. The relief pitchers have inherited 121 base runners for the year with 30.6% of them ended up scoring. The Cubs have sent 425 relief pitchers to the hill over the course of the season.

The Cubs have turned 71.7% of balls in play into outs out of 10,473 innings on the field, which has them sitting at 3rd in baseball. The Boston Red Sox have notched a total of 3,491 putouts this season, in addition to 1,104 assists and 53 errors. Their fielding percentage is currently at .989 which has them ranked 4th in the majors, and they have turned 101 double plays.

Boyd has taken the mound for 1,056 innings and has earned 1,020 K's so far in his MLB career. His ERA is 4.53 (532 earned runs allowed) and his career WHIP is 1.275. He has given up 1,020 base hits (8.7 hits per nine innings) and has 327 walks. Boyd (58-75 win-loss record in his career) sits with a FIP of 4.47 while facing 4,479 opposing hitters in the major leagues.

The San Francisco Giants are sitting with an OBP of .308 as well as a team batting average of .231 over the course of the season. They have been called out on strikes on 1,132 instances (8th in MLB) and have 1,005 base hits. San Francisco has 128 HRs for the year as well as 504 runs batted in. The Giants have a SLG% of .376 and they have an average of 4.05 runs per contest (25th in baseball). They have put up 196 two-baggers, while getting a free base 444 times and scoring 530 runs.

The San Francisco pitching staff have allowed 540 runs on the campaign while holding an ERA of 3.74 (481 earned runs surrendered). They have conceded 114 home runs and they give up 4.20 runs per 9 innings (10th in baseball). The Giants are sitting with a team WHIP of 1.286 and have a FIP of 3.71 as a unit for the year. Their K/BB ratio sits at 8.50 (1,095 strikeouts vs 411 free passes). They are currently ranked 19th in the league as a staff in total hits given up with 1,079.

With 118 save situations, the Giants have amassed 70 holds in addition to 18 blown saves. San Francisco has had relief pitchers enter the game in 48 save chances and they have come away with 30 saves. Their relief pitchers have come in 143 times in high leverage situations and on 94 occasions with base runners. San Francisco relief pitchers have an inherited score percentage of 34.7% of 150 inherited runners. They are currently ranked 17th in the league holding a save percentage of 62.5%, and they have sent 417 bullpen pitchers to the hill on the campaign.

In their 10,428 innings on the diamond, the Giants hold a efficiency on defense of 68.7% (26th in professional baseball). The San Francisco Giants have gotten 104 double plays and own a fielding percentage of .984 (26th in professional baseball). The Giants have recorded 1,229 assists, 78 errors and have earned a total of 3,476 putouts on the season.

Verlander (263-157 record in his career) has a 3.34 ERA while giving up 7.7 hits per 9 innings. His strikeout to walk ratio is 3.55 and he has gone up against 14,434 hitters in his MLB career. He has given up 1,309 ER's while holding a WHIP of 1.135 and having a FIP of 3.3. In his career, Verlander has allowed 3,013 base knocks while he has tallied 3,515 punch outs in 3,525 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (-160)

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