Colorado Rockies vs San Diego Padres Prediction, 9/11/2025 MLB Picks, Best Bets & Odds

Game: Colorado Rockies vs San Diego Padres

Date: Thursday, September 11, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Colorado (+132) San Diego (-160)

Petco Park is the site where the San Diego Padres (79-66) will compete against the Colorado Rockies (40-105) on Thursday. The odds on this game have Colorado at +132 while San Diego is sitting at -160. The over/under has been set at 8. The pitchers who are expected to start will be McCade Brown and Randy Vasquez.

Colorado has a slugging % of .392 and have been called out on strikes 1,351 times, while drawing a walk on 360 occasions. They have 531 runs batted in and 1,166 base knocks on the season, while their batting average is at .240. The Rockies have tallied 234 two-baggers as a team and have hit 144 baseballs out of the park. They have earned a total of 545 runs while holding a team on-base percentage of .297. As a squad, the Colorado Rockies are putting up 3.8 runs per outing, which puts them at 29th in the league.

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They have a K/BB ratio of 1.93 and their pitching staff has a team WHIP of 1.60. Rockies pitchers have yielded 221 long balls and 922 runs (30th in baseball). Colorado has surrendered 1,520 base hits (10.8 per 9 innings) as well as 844 earned runs. The Rockies have compiled a team ERA of 6.01 on the year (30th in baseball), and their staff has struck out 971 batters. Their pitching staff has walked 503 players from the other team and their FIP comes in at 5.22 as a squad so far this season.

The Rockies have dispatched 478 relievers to the hill this year. The relievers have inherited 254 base runners on the year with 36.6% of those runners ended up scoring. They have tallied 26 saves this year and have not converted 24 out of their 50 save opportunities. The Rockies relievers have accumulated a save percentage of 52.0% and stepped onto the hill in 101 save situations. The bullpen have tallied 51 holds this season (30th in baseball). Rockies relief pitchers have come into the game with opponents on base 149 times in addition to having 129 appearances in high leverage situations.

The Cleveland Guardians have notched a total of 3,793 putouts on the year, in addition to 1,341 assists and 101 errors. Their fielding rate is at .981 which has them ranked 29th in the majors, and have 142 double plays. The Rockies have transformed 65.7% of balls hit into play into outs out of 11,379 innings on the diamond, which has them ranked 30th in pro baseball.

Brown has taken the hill for 9 innings and has earned 6 strikeouts so far in his pro baseball career. Brown (0-3 career record) holds a FIP of 12.66 while he has gone up against 53 hitters during his time in the major leagues. His ERA is 12.86 (13 earned runs allowed) and he has a WHIP of 2.418. He has conceded 15 base knocks (14.8 hits per 9 innings) and has 7 walks.

San Diego has recorded 127 HRs for the season as well as 579 RBIs. They have hit 237 two-baggers, while getting a free base 465 times and putting up 616 runs. The San Diego Padres have an on-base percentage of .321 in addition to a batting average of .252 on the campaign. The Padres hold a team SLG% of .386 and they tally 4.25 runs per contest (23rd in baseball). They have been rung up on 1,030 occasions (28th in the league) and are sitting with 1,220 base knocks.

The Padres have a WHIP of 1.209 in addition to having a FIP of 4.03 as a team so far this year. They are currently ranked 1st in the league as a pitching staff in total hits conceded with 1,073. The San Diego pitching staff have yielded 563 runs this year while holding an ERA of 3.66 (521 earned runs surrendered). Their K/BB ratio is 8.80 (1,254 strikeouts vs 476 walks). They have surrendered 157 home runs and they concede 3.96 runs per 9 innings (4th in the league).

San Diego relief pitchers have an inherited score percentage of 28.8% out of their 233 inherited base runners. Their relief pitchers have taken the field 193 times in high leverage situations and also on 164 occasions with base runners. Sitting with 155 save situations, the Padres have compiled 91 holds and also 15 blown saves. They rank 1st in baseball with a save percentage of 74.6%, and they have dispatched 514 relief pitchers onto the field this season. San Diego has called on bullpen pitchers to step onto the mound in 59 save opportunities and they have come away with 44 saves.

In 11,529 innings on the field, the Padres have a defensive efficiency of 71.8% (2nd in the majors). The San Diego Padres have turned 105 double plays and have a fielding percentage of .987 (13th in baseball). The Padres have accrued 1,093 assists, 67 errors and have a total of 3,843 putouts for the year.

Thus far in his career, Vasquez has given up 262 base knocks while accumulating 157 strikeouts in 252 innings. Vasquez (10-15 win-loss mark in his career) holds a 4.14 earned run average while allowing 9.3 hits per nine innings. He has given up a total of 116 ER's while holding a WHIP of 1.419 and having a FIP of 4.1. He has a strikeout to walk ratio of 1.64 and he has gone up against 1,103 batters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-160)

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