Colorado Rockies vs San Francisco Giants Prediction, 9/28/2025 MLB Picks, Best Bets & Odds

Game: Colorado Rockies vs San Francisco Giants

Date: Sunday, September 28, 2025

Location: Oracle Park in San Francisco, CA

TV: NBC Bay Area

Odds/Point Spread: Colorado (+150) San Francisco (-182)

The San Francisco Giants (78-81) are welcoming the Colorado Rockies (43-116) at Oracle Park on Sunday. The odds on this game have Colorado at +150 and San Francisco is sitting at -182. The total is set at 9. The men taking the mound will be McCade Brown and Logan Webb.

As a squad, the Colorado Rockies are scoring 3.7 runs per outing, which has them sitting at 29th in the league. They have a total of 591 runs scored while holding a team on-base percentage of .294. The Rockies have tallied 250 two-baggers as a team and have knocked 156 baseballs out of the park. They have earned 575 RBI's in addition to 1,264 base knocks over the course of the season, while their team batting average is at .238. Colorado is slugging .387 and have been rung up 1,497 times, while being walked on 390 occasions.

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They have accrued a K/BB ratio of 1.99 and their pitching staff holds a collective WHIP of 1.59. Rockies pitchers have surrendered 246 home runs and also 1,007 runs in total (30th in the league). Colorado has conceded 1,655 hits (10.8 per 9 innings) and 921 earned runs. The Rockies hold a team ERA of 5.99 on the year (30th in baseball), and their staff has struck out 1,076 hitters. They have walked 541 batters and their FIP sits at 5.22 as a unit this season.

Rockies relief pitchers have come into the game with players on base 159 times in addition to having 139 appearances in high leverage situations. The relief pitchers have a total of 61 holds on the year (30th in the league). The Rockies bullpen have recorded a save percentage of 53.7% and have stepped onto the mound in 115 save situations. They have compiled 29 saves this year and have missed out on 25 of 54 save chances. The bullpen pitchers have inherited 274 runners for the year and 35.4% of those runners crossed the plate. The Rockies have sent 521 relief pitchers to the hill on the campaign.

The Cleveland Guardians are sitting with 4,150 putouts this year, in addition to 1,445 assists and 109 errors. Their fielding percentage is at .981 which ranks 29th in pro baseball, and have accumulated 154 double plays. The Rockies have converted 65.9% of balls in play into outs out of their 12,450 innings on the diamond, which has them ranked 30th in professional baseball.

Brown (0-4 career win-loss mark) sits with a FIP of 7.59 and he has faced 112 hitters during his time in the majors. He has allowed 26 base knocks (10.5 hits per 9 innings) and has had 15 walks. His earned run average is 7.70 (19 earned runs allowed) and his career WHIP is 1.847. Brown has thrown 22 frames and has accounted for 21 punch outs during his career.

The San Francisco Giants have accounted for an OBP of .311 as well as a batting average of .235 for the year. They have been called out on strikes on 1,363 instances (11th in baseball) and have 1,243 hits. San Francisco has recorded 168 home runs for the season to go along with 658 runs batted in. The Giants have a team slugging % of .385 and they have an average of 4.35 runs per contest (17th in MLB). They have notched 236 two-baggers, while taking a walk 543 times as well as putting up 691 runs.

The Giants have a WHIP of 1.306 in addition to having a FIP of 3.76 as a team so far this year. They are sitting at 21st in the league as a pitching staff in total hits given up with 1,336. The San Francisco pitching staff have allowed 678 runs this year while holding an ERA of 3.88 (606 earned runs conceded). Their K/BB ratio comes in at 8.50 (1,324 strikeouts vs 501 free passes). They have conceded 139 homers and they give up 4.34 runs per 9 innings (16th in baseball).

San Francisco relievers hold an inherited score percentage of 37.2% out of 191 inherited runners. Their relievers have stepped onto the mound 170 times in high leverage situations and on 121 occasions with runners on. With 143 save situations, the Giants have amassed 83 holds and also 22 blown saves. They are ranked 16th in MLB with a save percentage of 63.3%, and they have dispatched 506 bullpen pitchers to the hill so far this season. San Francisco has called on relievers to step onto the hill in 60 save opportunities and they have recorded 38 saves.

In their 12,660 innings on the field, the Giants have accumulated a efficiency on defense of 68.3% (28th in MLB). The San Francisco Giants have gotten 132 double plays and have a fielding rate of .984 (24th in pro baseball). The Giants have racked up 1,498 assists, 93 errors and have earned 4,220 putouts over the course of the season.

So far in his MLB career, Webb has surrendered 1,017 base hits while he has totaled 986 punch outs in 1,056 frames. Webb (69-53 career win-loss record) is the owner of a 3.40 earned run average while giving up 8.7 hits per 9 innings. He has given up a total of 399 ER's while holding a WHIP of 1.199 and being the owner of a FIP of 3.3. His K/BB ratio is 3.94 and he has faced 4,331 hitters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Colorado (+150)

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