Los Angeles Angels vs Houston Astros Prediction, 9/1/2025 MLB Picks, Best Bets & Odds
Game: Los Angeles Angels vs Houston Astros
Date: Monday, September 1, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Los Angeles (+220) Houston (-275)
The Houston Astros (74-60) welcome the Los Angeles Angels (62-71) at Daikin Park on Monday. The moneyline on this game has Los Angeles at +220 while Houston is priced at -275. The over/under comes in at 8. The expected starting pitchers are Yusei Kikuchi and Framber Valdez.


Los Angeles is slugging .405 and have struck out 1,304 times, while being walked on 402 occasions. They have 555 RBI's and 1,023 hits on the year, and their team batting average sits at .230. The Angels have recorded 184 two-baggers as a team and have knocked 188 baseballs out of the park. They have accounted for 574 runs while holding a team OBP of .303. As a unit, the Los Angeles Angels are scoring 4.3 runs per game, which is 17th in the league.
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The Angels have a team earned run average of 4.81 over the course of the season (28th in the league), and they have rung up 1,049 hitters. Angels pitchers have given up 186 home runs and also 679 total runs (27th in the league). They have walked 506 hitters and their FIP sits at 4.78 as a unit this year. Los Angeles has surrendered 1,189 base hits (9.1 per 9 innings) and also 630 earned runs. Their K/BB ratio is 2.07 and their pitching staff has a collective WHIP of 1.44.
Angels relief pitchers have come into the game with opponents on base 126 times as well as having 174 appearances in high leverage situations. The relief pitchers have a total of 71 holds so far this season (20th in MLB). The Angels relief pitchers have recorded a save percentage of 51.7% and have come into the game in 132 save situations. They have earned 30 saves on the campaign and have blown 28 of their 58 chances to save the game. The relief pitchers have inherited 193 runners so far this season with 36.8% of them crossed home plate. The Angels have dispatched 463 relievers to the hill on the year.
The Kansas City Royals have a tally of 3,537 putouts so far this season, as well as 1,171 assists and 76 errors. Their fielding percentage is currently at .984 which is 23rd in pro baseball, and they have turned 135 double plays. The Angels have turned 68.7% of balls hit into play into outs in their 10,611 innings on the diamond, which has them ranked 26th in MLB.
Kikuchi (47-56 career mark) has earned a FIP of 4.36 and he has gone up against 4,137 batters during his time in the major leagues. He has allowed 962 base hits (9.0 hits per 9 innings) and has had 346 walks. His ERA is 4.43 (474 earned runs allowed) and his WHIP is 1.358. Kikuchi has taken the ball for 963 innings and is sitting with 993 strikeouts in his pro baseball career.
The Houston Astros have earned an on-base percentage of .318 in addition to a team batting average of .253 on the campaign. They have struck out on 1,062 occasions (23rd in the league) and have totaled 1,149 base hits. Houston has 151 long balls on the campaign and 544 runs batted in. The Astros hold a slugging percentage of .402 and they are recording 4.25 runs per contest (20th in the league). They have put up 202 two-baggers, while getting a free base 393 times and scoring 569 runs.
The Astros have a team WHIP of 1.221 with a FIP of 3.94 as a unit on the year. They are sitting at 5th in the league as a pitching staff in total hits relinquished with 1,044. The Houston pitching staff have allowed 550 runs this season while holding a team ERA of 3.86 (512 earned runs relinquished). Their strikeout to walk ratio is 9.50 (1,262 strikeouts vs 413 free passes). They have conceded 161 homers and they give up 4.15 runs per 9 innings (7th in MLB).
Houston relief pitchers hold an inherited score rate of 25.4% out of 138 inherited runners. Their relief pitchers have stepped onto the mound 138 times in high leverage situations and on 102 occasions with runners on. With 132 save situations, the Astros have 76 holds and also 14 blown saves. They are ranked 2nd in the league with a save rate of 73.6%, and they have sent 424 bullpen pitchers to the mound for the season. Houston has had relief pitchers step onto the hill in 53 save chances and they have come away with 39 saves.
The Houston Astros have turned 90 double plays and have notched a fielding percentage of .988 (7th in baseball). The Astros have 1,068 assists, 55 errors and have accounted for 3,554 putouts on the campaign. Out of their 10,662 innings on the field, the Astros have earned a defensive efficiency of 70.5% (10th in MLB).
In his pro baseball career, Valdez has surrendered 880 base hits while he has tallied 1,024 punch outs in 1,052 innings pitched. He has conceded 384 ER's while earning a WHIP of 1.195 and a FIP of 3.2. He has a K/BB ratio of 2.72 and he has faced 4,356 opposing batters during his MLB career. Valdez (80-48 mark in his career) is the owner of a 3.28 earned run average while allowing 7.5 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Los Angeles (+220)
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Additional Resources:
Houston Astros - Twitter
Los Angeles Angels - Twitter