New York Mets vs Philadelphia Phillies Prediction, 9/10/2025 MLB Picks, Best Bets & Odds

Game: New York Mets vs Philadelphia Phillies

Date: Wednesday, September 10, 2025

Location: Citizens Bank Park in Philadelphia, PA

TV: NBC Sports Philadelphia

Odds/Point Spread: New York (+125) Philadelphia (-145)

The New York Mets (76-68) are en route to Citizens Bank Park on Wednesday where they will take on the Philadelphia Phillies (84-60). The line on this matchup has New York at +125 while Philadelphia is sitting at -145. The total is set at 8. The pitchers taking the mound will be Clay Holmes and Cristopher Sanchez.

As a unit, the New York Mets are notching 4.8 runs per outing, which has them at 9th in baseball. They have accumulated 684 runs scored and hold an OBP of .329. The Mets have hit 239 doubles as a squad and have hit 197 baseballs out of the park. They have compiled 667 runs batted in in addition to 1,212 hits this season, and their team batting average is .250. New York has a slugging rate of .429 and have been rung up 1,156 times, while taking a walk on 511 occasions.

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They have accrued a K/BB ratio of 2.43 and the pitching staff has a collective WHIP of 1.32. Mets pitchers have yielded 128 home runs and 619 total runs (15th in MLB). New York has surrendered 1,175 base hits (8.3 per 9 innings) as well as 553 earned runs. The Mets have a team ERA of 3.91 on the year (13th in baseball), and their staff has rung up 1,238 batters. Their pitching staff has walked 510 players from the other team and their FIP sits at 3.86 as a unit so far this year.

Mets bullpen pitchers have stepped onto the hill with runners on base 154 times and also have had 170 appearances in high leverage situations. The relief pitchers have notched 89 holds on the season (8th in the league). The Mets relief pitchers have a save percentage of 61.3% and have entered the game in 151 save situations. They have accumulated 38 saves so far this season and have missed out on 24 of their 62 chances to get a save. The relievers have inherited 232 runners over the course of the season and 33.6% of them ended up crossing the plate. The Mets have dispatched 469 relievers to the hill on the year.

The Minnesota Twins have earned a total of 3,819 putouts this year, in addition to 1,292 assists and 67 errors. Their fielding percentage is at .987 which has them ranked 10th in the majors, and have accumulated 107 double plays. The Mets have turned 69.0% of balls hit into play into outs out of 11,457 innings on the diamond, which has them ranked 23rd in the majors.

Holmes has taken the hill for 484 innings and has 477 strikeouts during his career. Holmes (35-29 win-loss record in his career) sits with a FIP of 3.63 and he has gone up against 2,090 opposing batters during his time in the major leagues. His earned run average is 3.68 (198 earned runs allowed) and he has a career WHIP of 1.310. He has surrendered 422 base knocks (7.8 hits per 9 innings) with 212 free passes.

Philadelphia has recorded 178 home runs for the year as well as 658 runs batted in. They have recorded 237 doubles, while getting a free base 473 times and racking up 683 runs. The Philadelphia Phillies have recorded a team on-base percentage of .328 in addition to a team batting average of .258 for the season. The Phillies hold a team slugging percentage of .425 and they average 4.74 runs per contest (10th in baseball). They have struck out on 1,163 instances (20th in MLB) and have tallied 1,265 base hits.

The Philadelphia pitching staff have surrendered 575 runs on the season while having an ERA of 3.79 (538 earned runs relinquished). They have given up 152 home runs and they yield 4.05 runs per 9 innings (5th in baseball). The Phillies are sitting with a team WHIP of 1.241 and have a FIP of 3.67 as a squad so far this season. They have earned a K/BB ratio of 9.20 (1,310 strikeouts vs 393 bases on balls). They are sitting at 18th in baseball as a staff in total hits surrendered with 1,192.

Philadelphia bullpen pitchers have an inherited score rate of 32.9% of 140 inherited runners. Their relief pitchers have taken the field 160 times in high leverage situations and on 95 occasions with runners on base. With 140 save situations, the Phillies have accrued 73 holds in addition to 23 blown saves. They are ranked 12th in MLB holding a save rate of 64.1%, and they have sent 450 relievers onto the field this season. Philadelphia has called on relievers to step onto the mound in 64 save opportunities and they have come away with 41 saves.

The Philadelphia Phillies have gotten 92 double plays and have accounted for a fielding rate of .989 (3rd in professional baseball). The Phillies have accrued 1,241 assists, 54 errors and have amassed 3,832 putouts on the season. Out of their 11,496 innings on the field, the Phillies have a defensive efficiency of 68.9% (24th in baseball).

Sanchez (29-21 win-loss record in his career) has earned a 3.32 earned run average and has allowed 8.5 hits per 9 innings. He has a K/BB ratio of 3.83 and he has gone up against 2,102 batters so far in his MLB career. He has conceded a total of 188 earned runs while holding a WHIP of 1.188 and being the owner of a FIP of 3.3. In his MLB career, Sanchez has surrendered 479 base hits while totaling 483 strikeouts in 509 frames.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Philadelphia (-145)

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