San Francisco Giants vs Cincinnati Reds Prediction, 3/29/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Cincinnati Reds

Date: Saturday, March 29, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: San Francisco (-132) Cincinnati (+110)

The Cincinnati Reds (77-85 last season) will try to defeat the San Francisco Giants (80-82 last year) at Great American Ball Park on Saturday. The moneyline on this game has San Francisco at -132 while Cincinnati is opening at +110. The total comes in at 8.5. The expected starting pitchers will be Justin Verlander and Nick Lodolo.

The Giants tallied 266 doubles as a squad and smacked 177 balls out of the park. San Francisco had a slugging percentage of .396 and were called out on strikes 1,452 times, while taking a walk on 492 occasions. As a squad, the San Francisco Giants notched 4.3 runs per game, which was 17th in the league. They recorded 661 RBI's and 1,303 base knocks over the course of last season, while their team batting average finished at .239. They earned a total of 693 runs scored while holding a team on-base percentage of .305.

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They accrued a K/BB ratio of 2.73 and the pitching staff recorded a WHIP of 1.30. Giants pitchers allowed 153 home runs and 699 total runs (17th in the league). San Francisco surrendered 1,339 base hits (8.4 per 9 innings) and also 653 earned runs. The Giants had a team ERA of 4.10 for the previous season (19th in the league), and they rung up 1,436 hitters. They walked 526 players from the other team and their FIP was 3.80 as a unit last year.

The Giants had dispatched 564 relief pitchers to the mound over the course of last season. The relievers inherited 194 runners in the prior season with 35.1% of those players ended up scoring. They recorded 36 saves last season and blew 19 of their 55 chances to save the game. The Giants relief pitchers had a save percentage of 65.5% and entered the game in 157 save situations. The relief pitchers finished with 99 holds in the previous season (7th in baseball). Giants pitchers entered the game with players on base 132 times and also had 155 contests in high leverage situations.

The Seattle Mariners earned 4,301 putouts in the prior season, as well as 1,558 assists and 87 errors. Their fielding percentage finished at .986 which was 10th in baseball, and they turned 135 double plays. The Giants converted 68.3% of baseballs in play into outs out of their 12,903 innings on the diamond, which ranked them 26th in baseball.

Verlander has taken the hill for 3,415 innings and has totaled 3,416 strikeouts so far in his pro baseball career. His ERA is 3.30 (1,252 ER's allowed) and his WHIP is 1.125. He has surrendered 2,891 base hits (7.6 hits per nine innings) and has 952 walks. Verlander (262-147 career record) is the owner of a FIP of 3.25 while going up against 13,945 opposing batters during his time in the major leagues.

The Cincinnati Reds earned an on-base percentage of .305 as well as a batting average of .231 over the course of last season. They struck out on 1,459 instances (9th in the league) and earned 1,230 hits. Cincinnati accounted for 174 home runs last year and 663 RBIs. The Reds held a team slugging % of .388 and they were recording 4.31 runs per game (16th in baseball). They hit 257 two-baggers, while walking 496 times and scoring 699 runs.

The Reds finished with a team WHIP of 1.253 and were the owners of a FIP of 4.25 as a unit in the previous season. Their strikeout to walk ratio came in at 8.60 (1,370 strikeouts vs 487 bases on balls). They were sitting at 13th in the league as a staff in total hits surrendered with 1,302. They allowed 196 home runs and they relinquished 4.37 runs per 9 innings (16th in MLB). The Cincinnati pitching staff yielded 694 runs for the prior year while having an ERA of 4.09 (649 earned runs surrendered).

Cincinnati called on relief pitchers to step onto the hill in 51 save opportunities and they walked away with 36 saves. They were ranked 3rd in baseball holding a save percentage of 70.6%, and they dispatched 534 bullpen pitchers to the hill last season. Their relief pitchers came in 155 times in high leverage situations in addition to 145 occasions with runners on base. Cincinnati relief pitchers held an inherited score percentage of 31.1% out of their 225 inherited base runners. With 132 save situations, the Reds had 78 holds and also 15 blown saves.

The Cincinnati Reds had 100 double plays and held a fielding percentage of .983 (27th in baseball). The Reds had 1,213 assists, 96 errors and earned a total of 4,284 putouts for the previous season. Out of their 12,852 innings on the diamond, the Reds finished with a defensive efficiency of 70.2% (15th in the majors).

So far in his career, Lodolo has surrendered 241 hits while he has totaled 300 punch outs in 253 frames. He has surrendered a total of 127 earned runs while earning a WHIP of 1.292 and a FIP of 4.5. He has a K/BB ratio of 3.49 and he has faced 1,100 hitters in his MLB career. Lodolo (15-14 career win-loss mark) has earned a 4.52 earned run average while giving up 8.6 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Cincinnati (+110)

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