Washington Nationals vs Miami Marlins Prediction, 9/10/2025 MLB Picks, Best Bets & Odds
Game: Washington Nationals vs Miami Marlins
Date: Wednesday, September 10, 2025
Location: loanDepot park in Miami, FL
TV: FanDuel Sports Network Florida
Odds/Point Spread: Washington (+110) Miami (-130)
The Miami Marlins (66-78) host the Washington Nationals (59-84) at loanDepot park on Wednesday. The line on this matchup has Washington at +110 and Miami is opening at -130. The betting total comes in at 8.5. The starting pitchers will be Jake Irvin and Eury Perez.


The Nationals have accumulated 236 doubles as a squad and have smacked 138 baseballs out of the stadium. Washington has a slugging percentage of .391 and have struck out 1,157 times, while being walked on 406 occasions. As a team, the Washington Nationals are recording 4.3 runs per game, which has them at 19th in the league. They have 593 runs batted in in addition to 1,170 base knocks this season, while their team batting average is at .245. They have racked up 616 runs scored and hold an OBP of .309.
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The Nationals have a team ERA of 5.30 over the course of the season (29th in the league), and the staff has struck out 1,097 batters. Nationals pitchers have conceded 188 home runs and also 780 total runs (29th in the league). Their pitching staff has walked 496 opposing players and their FIP is 4.72 as a team on the season. Washington has conceded 1,300 base hits (9.3 per 9 innings) in addition to 738 earned runs. They have a strikeout to walk ratio of 2.21 and the pitching staff has a collective WHIP of 1.43.
The Nationals have sent 508 relief pitchers to the mound so far this year. The relief pitchers have inherited 235 base runners for the season and 38.7% of those players earned a run for their team. They have accumulated 30 saves so far this season and have missed out on 15 of 45 chances to save the game. The Nationals relievers have a save percentage of 66.7% and have come into the game in 112 save situations. The relief pitchers have accumulated 66 holds this season (25th in MLB). Nationals pitchers have come into the game with opponents on base 139 times and also have had 108 appearances in high leverage situations.
The Washington Nationals have earned a total of 3,763 putouts this season, in addition to 1,218 assists and 77 errors. Their fielding rate is at .985 which has them sitting 19th in MLB, and have accumulated 111 double plays. The Nationals have converted 68.3% of balls hit into play into outs out of 11,289 innings, which has them sitting at 28th in baseball.
Irvin has taken the ball for 465 innings and has accumulated 359 strikeouts so far in his career. Irvin (21-32 mark in his career) holds a FIP of 4.84 while he has faced 1,992 batters in the major leagues. His earned run average is 4.91 (254 earned runs allowed) and his career WHIP is 1.341. He has surrendered 461 base hits (8.9 hits per 9 innings) with 163 walks.
The Marlins have a team slugging % of .393 and they score 4.33 runs per outing (18th in the league). They have put up 241 doubles, while getting a free base 435 times and putting up 623 runs. Miami has compiled 137 home runs over the course of the season and 592 runs batted in. They have been rung up on 1,129 occasions (26th in the league) and have tallied 1,228 base hits. The Miami Marlins have earned an on-base percentage of .314 and a team batting average of .250 this year.
The Miami pitching staff have allowed 731 runs so far this season while holding a team ERA of 4.80 (680 earned runs relinquished). They have given up 174 dingers and they give up 5.16 runs per 9 innings (26th in the league). The Marlins have a WHIP of 1.325 and are the owners of a FIP of 4.37 as a team this season. They currently have a K/BB ratio of 8.00 (1,131 strikeouts vs 454 walks). They come in at 22nd in MLB as a staff in total hits surrendered with 1,237.
Miami has had bullpen pitchers take the mound in 55 save chances and they have walked away with 35 saves. They sit at 14th in baseball holding a save percentage of 63.6%, and they have dispatched 449 relief pitchers onto the field over the course of the season. Their relief pitchers have stepped onto the hill 151 times in high leverage situations in addition to 111 occasions with runners on. Miami relief pitchers have an inherited score percentage of 33.1% of 163 inherited runners. Sitting with 132 save situations, the Marlins have recorded 75 holds and 20 blown saves.
In 11,487 innings played, the Marlins are sitting with a efficiency on defense of 69.7% (16th in the majors). The Miami Marlins have gotten 96 double plays and have notched a fielding percentage of .986 (16th in the majors). The Marlins have 1,223 assists, 73 errors and have earned a total of 3,829 putouts for the year.
So far in his career, Perez has allowed 127 base hits while earning 180 strikeouts in 166 innings pitched. Perez (11-11 career mark) has a 3.84 ERA while surrendering 6.9 hits per 9 innings. He has surrendered a total of 71 earned runs while earning a WHIP of 1.119 and having a FIP of 3.8. His K/BB ratio is 3.05 and he has faced 681 opposing hitters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Washington (+110)
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Additional Resources:
Miami Marlins - Twitter
Washington Nationals - Twitter