Atlanta Braves vs Washington Nationals Prediction, 4/22/2026 MLB Picks, Best Bets & Odds

Game: Atlanta Braves vs Washington Nationals

Date: Wednesday, April 22, 2026

Location: Nationals Park in Washington, D.C.

TV: Nationals.TV

Odds/Point Spread: Atlanta (+110) Washington (-130)

The Atlanta Braves (16-7) are traveling to Nationals Park on Wednesday where they will try to defeat the Washington Nationals (10-13). The moneyline on this game has the Braves at +110 and the Nationals are coming in at -130. The over/under is 8.5. The pitchers who are expected to start will be Martin Perez and Zack Littell.

The Braves have tallied 43 doubles as a unit and have smacked 30 balls out of the stadium. Atlanta owns a slugging percentage of .446 and have been called out on strikes 174 times, while taking a walk on 77 occasions. As a unit, the Atlanta Braves are putting up 5.7 runs per game, which is 2nd in MLB. They have earned 128 RBI's as well as 218 base knocks over the course of the season, while their team batting average is .274. They have racked up 131 runs while holding a team OBP of .342.

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The Braves are sitting with a team ERA of 2.68 so far this season (1st in baseball), and they have rung up 186 hitters. Braves pitchers have relinquished 18 home runs in addition to 69 runs (1st in MLB). They have walked 64 opposing players and their FIP is 3.57 as a team so far this season. Atlanta has relinquished 152 hits (6.7 per 9 innings) as well as 61 earned runs. Their strikeout to walk ratio is 2.91 and their pitching staff has earned a collective WHIP of 1.05.

Braves pitchers have gone to the mound with players on base 15 times in addition to having 20 appearances in high leverage situations. The bullpen have earned 14 holds on the year (12th in baseball). The Braves relief pitchers have earned a save rate of 100.0% and stepped onto the hill in 24 save situations. They have recorded 9 saves over the course of the season and have missed out on 0 of 9 chances to save the game. The relief pitchers have inherited 22 base runners over the course of the season and 22.7% of those runners earned a run for their team. The Braves have dispatched 71 relief pitchers to the hill so far this season.

The Braves have converted 74.0% of balls hit into play into outs out of their 1,845 innings, which has them ranked 1st in professional baseball. The Athletics have 615 putouts on the year, in addition to 191 assists and 10 errors. Their fielding percentage is at .988 which has them sitting 9th in the majors, and have earned 23 double plays.

Perez has pitched in 1,651 innings and has earned 1,163 strikeouts during his career. His ERA is 4.39 (805 ER's allowed) and his WHIP is 1.429. He has given up 1,763 base hits (9.6 hits per 9 innings) and has had 596 walks. Perez (92-94 career record) is the owner of a FIP of 4.32 and he has gone up against 7,149 opposing batters in the major leagues.

Washington has hit 25 HRs on the year and 114 runs batted in. They have hit 41 two-baggers, while walking 76 times as well as putting up 125 runs. The Washington Nationals have a team OBP of .327 as well as a team batting average of .252 over the course of the season. The Nationals hold a slugging % of .400 and they tally 5.43 runs per game (3rd in MLB). They have struck out on 186 instances (20th in baseball) and have 203 base hits.

The Nationals have a team WHIP of 1.543 in addition to having a FIP of 5.53 as a staff this season. They sit at 30th in the league as a staff in total hits allowed with 223. The Washington pitching staff have relinquished 143 runs on the season and come in with a team ERA of 5.71 (132 earned runs surrendered). Their K/BB ratio comes in at 7.70 (178 strikeouts vs 98 free passes). They have allowed 40 dingers and they allow 6.19 runs per 9 innings (30th in the league).

With 29 save situations, the Nationals have accrued 12 holds in addition to 8 blown saves. Washington has had relievers step onto the mound in 13 save opportunities and they have come away with 5 saves. Washington relief pitchers hold an inherited score percentage of 44.7% out of their 38 inherited base runners. Their relief pitchers have stepped onto the mound 22 times in high leverage situations and also on 24 occasions with runners on. They rank 29th in the league holding a save rate of 38.5%, and they have sent 82 relievers to the hill this season.

In their 1,872 innings played, the Nationals have accumulated a defensive efficiency of 67.9% (26th in baseball). The Washington Nationals have turned 19 double plays and have a fielding percentage of .973 (30th in the majors). The Nationals have 220 assists, 23 errors and have amassed 624 putouts for the year.

During his career, Littell has conceded 624 hits while accumulating 510 punch outs in 621 innings. He has given up 275 earned runs while earning a WHIP of 1.231 and a FIP of 3.9. He has a K/BB ratio of 3.62 and he has gone up against 2,603 batters in his career. Littell (34-31 career record) holds a 3.98 earned run average and has conceded 9.0 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Washington (-130)

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