Cleveland Guardians vs Seattle Mariners Prediction, 3/28/2026 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Seattle Mariners

Date: Saturday, March 28, 2026

Location: T-Mobile Park in Seattle, WA

TV: MLB.TV

Odds/Point Spread: Cleveland (+102) Seattle (-122)

T-Mobile Park is the location where the Seattle Mariners (90-72 last season) will try to beat the Cleveland Guardians (88-74 last year) on Saturday. The odds on this game have Cleveland at +102 while Seattle is at -122. The over/under is 8. The pitchers who are expected to start are Joey Cantillo and Bryan Woo.

Cleveland had a slugging % of .373 and were called out on strikes 1,344 times, while being walked on 494 occasions. They recorded 621 RBI's as well as 1,199 base knocks in the previous season, while their team batting average was .226. The Guardians accounted for 243 doubles as a unit and hit 168 balls out of the park. They accounted for 643 runs scored and held an on-base percentage of .296. As a team, the Cleveland Guardians notched 4.0 runs/g, which had them sitting at 28th in the league.

Get all of our MLB Parlay Picks

The Guardians held a team ERA of 3.70 over the course of last year (5th in baseball), and the staff rung up 1,381 hitters. Guardians pitchers surrendered 169 home runs and also 649 runs in total (8th in MLB). Their pitching staff walked 527 opposing hitters and their FIP finished at 3.95 as a team during the previous year. Cleveland surrendered 1,291 hits (8.1 per 9 innings) and also 593 earned runs. Their K/BB ratio was 2.62 and their pitching staff recorded a WHIP of 1.26.

Guardians relief pitchers entered the contest with runners on base 151 times as well as having 192 games in high leverage situations. The bullpen recorded 112 holds over the course of last season (2nd in the league). The Guardians bullpen earned a save percentage of 68.1% and stepped onto the mound in 184 save situations. They accumulated 47 saves during the previous year and missed out on 22 of 69 chances to save the game. The relievers inherited 209 runners during the previous year with 32.5% of those players crossed home plate. The Guardians dispatched 531 relief pitchers to the hill in the previous season.

The Guardians turned 69.8% of balls in play into outs out of 12,978 innings on the field, which had them sitting at 17th in the majors. The Cincinnati Reds earned a total of 4,326 putouts in the prior season, as well as 1,330 assists and 99 errors. Their fielding rate finished at .985 which ranked 21st in MLB, and accumulated 121 double plays.

Cantillo has taken the hill for 133 innings and has tallied 152 strikeouts in his career. Cantillo (7-7 record in his career) has a FIP of 3.66 while he has gone up against 564 opposing batters in the majors. His ERA is 3.71 (55 earned runs allowed) and his career WHIP is 1.275. He has given up 113 base hits (7.6 hits per nine innings) and has had 57 free passes.

The Mariners had a SLG% of .420 and they scored 4.73 runs per contest (10th in the league). They had 234 doubles, while walking 544 times and earning 766 runs. Seattle recorded 238 home runs last season to go along with 734 runs batted in. They struck out on 1,446 occasions (6th in the league) and earned a total of 1,345 base knocks. The Seattle Mariners held a team on-base percentage of .320 as well as a batting average of .244 last year.

The Mariners had a team WHIP of 1.221 and were the owners of a FIP of 3.98 as a team for the prior year. They earned a strikeout to walk ratio of 8.80 (1,426 strikeouts against 454 walks). They finished at 15th in the league as a pitching staff in total hits given up with 1,331. They gave up 192 dingers and they allowed 4.27 runs per 9 innings (13th in the league). The Seattle pitching staff conceded 694 runs in the previous season while having an ERA of 3.87 (629 earned runs allowed).

Seattle relievers held an inherited score rate of 25.2% of 147 inherited base runners. Their relievers took the field 216 times in high leverage situations and also on 132 occasions with runners on. Ending the season with 159 save situations, the Mariners had 90 holds in addition to 26 blown saves. They were ranked 19th in the league holding a save rate of 62.3%, and they sent 550 relief pitchers to the mound last year. Seattle had bullpen pitchers take the mound in 69 save opportunities and they tallied 43 saves.

In their 13,164 innings played, the Mariners had a defensive efficiency of 70.3% (12th in the majors). The Seattle Mariners turned 118 double plays and had a fielding percentage of .988 (7th in pro baseball). The Mariners had 1,355 assists, 69 errors and had 4,388 putouts over the course of last year.

Woo (28-15 win-loss mark in his career) is the owner of a 3.21 ERA and has given up 7.0 hits per nine innings. He has a K/BB ratio of 4.90 and he has faced 1,574 batters in his MLB career. He has conceded 141 earned runs while holding a WHIP of 0.982 and a FIP of 3.2. So far in his career, Woo has allowed 308 hits while tallying 392 K's in 395 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Cleveland (+102)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get MLB picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.