New York Yankees vs San Francisco Giants Prediction, 3/25/2026 MLB Picks, Best Bets & Odds

Game: New York Yankees vs San Francisco Giants

Date: Wednesday, March 25, 2026

Location: Oracle Park in San Francisco, CA

TV: Netflix

Odds/Point Spread: New York (-196) San Francisco (+162)

The San Francisco Giants (81-81 last year) will try to defeat the New York Yankees (94-68 last season) at Oracle Park on Wednesday. The odds on this game have New York at -196 while San Francisco is sitting at +162. The over/under is 8. The expected starting pitchers will be Max Fried and Logan Webb.

New York had a slugging percentage of .455 and were rung up 1,463 times, while taking a walk on 639 occasions. They accrued 820 RBI's and 1,371 hits last year, while their team batting average was .251. The Yankees tallied 255 two-baggers as a unit and hit 274 balls out of the stadium. They racked up 849 runs scored while holding a team on-base percentage of .332. As a team, the New York Yankees earned 5.2 runs per game, which had them sitting at 1st in the league.

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Their K/BB ratio was 2.59 and the pitching staff held a WHIP of 1.25. Yankees pitchers yielded 175 home runs and also 685 runs in total (15th in MLB). New York surrendered 1,239 base hits (7.7 per 9 innings) as well as 625 earned runs. The Yankees held a team earned run average of 3.91 over the course of last season (14th in MLB), and they struck out 1,440 batters. They walked 557 players from the other team and their FIP was 4.00 as a unit over the course of the prior season.

Yankees bullpen pitchers stepped onto the hill with players on base 167 times as well as having 165 games in high leverage situations. The bullpen earned 100 holds in the prior season (9th in the league). The Yankees relief pitchers recorded a save rate of 67.2% and entered the game in 166 save situations. They compiled 43 saves for the prior year and missed out on 21 out of their 64 chances to get a save. The relief pitchers inherited 255 runners for the previous season and 27.5% of those players crossed the plate. The Yankees had sent 533 relief pitchers to the mound over the course of the prior season.

The New York Yankees accumulated 4,319 putouts for the prior year, in addition to 1,389 assists and 94 errors. Their fielding percentage finished at .986 which had them ranked 13th in the majors, and had 105 double plays. The Yankees converted 70.8% of balls in play into outs out of their 12,957 innings on the field, ranking them 6th in pro baseball.

Fried (92-41 career record) has a FIP of 2.99 and he has gone up against 4,415 hitters in the major leagues. He has allowed 947 hits (7.9 hits per nine innings) with 297 free passes. His ERA is 3.04 (364 ER's allowed) and he has a WHIP of 1.153. Fried has thrown 1,079 innings and has racked up 1,052 punch outs in his MLB career.

San Francisco was sitting with 173 home runs for the prior year in addition to 672 RBIs. They hit 239 doubles, while walking 556 times and notching 705 runs. The San Francisco Giants had a team on-base percentage of .311 and a team batting average of .235 over the course of last season. The Giants had a team slugging % of .386 and they averaged 4.35 runs per contest (17th in baseball). They struck out on 1,380 occasions (12th in the league) and earned a total of 1,261 hits.

The Giants finished with a team WHIP of 1.298 with a FIP of 3.74 as a pitching staff over the course of last year. They earned a K/BB ratio of 8.50 (1,358 strikeouts vs 506 free passes). They had a ranking of 21st in MLB as a staff in total hits relinquished with 1,354. They gave up 143 long balls and they relinquished 4.30 runs per 9 innings (15th in the league). The San Francisco pitching staff given up 684 runs during the previous year while holding a team ERA of 3.84 (612 earned runs surrendered).

Wrapping up the year with 152 save situations, the Giants accrued 89 holds in addition to 22 blown saves. San Francisco had relief pitchers enter the game in 63 save opportunities and they tallied 41 saves. Their relievers took the field 173 times in high leverage situations in addition to 122 occasions with base runners. San Francisco relievers had an inherited score rate of 36.8% out of their 193 inherited base runners. They ranked 10th in MLB with a save percentage of 65.1%, and they sent 515 bullpen pitchers onto the field last year.

Out of their 12,903 innings on the field, the Giants accumulated a defensive efficiency of 68.4% (26th in the majors). The San Francisco Giants turned 134 double plays and held a fielding percentage of .984 (23rd in baseball). The Giants recorded 1,523 assists, 95 errors and earned a total of 4,301 putouts over the course of last season.

So far in his career, Webb has surrendered 1,020 base knocks while he has totaled 994 K's in 1,062 innings pitched. He has given up a total of 399 ER's while earning a WHIP of 1.196 and a FIP of 3.3. His strikeout to walk ratio is 3.98 and he has gone up against 4,350 opposing hitters thus far in his career. Webb (70-53 win-loss mark in his career) has a 3.38 ERA and has conceded 8.6 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take New York (-196)

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