Jackson State Tigers vs Louisville Cardinals Prediction, 11/6/2025 College Basketball Picks, Best Bets & Odds
Game: Jackson State Tigers vs Louisville Cardinals
Date: Thursday, November 6, 2025
Location: KFC Yum! Center in Louisville, KY
TV: ACC Extra
The Jackson State Tigers (16-18 last year) are en route to KFC Yum! Center on Thursday where they will take on the Louisville Cardinals (27-8 last season).

The Jackson State Tigers played Illinois and took a loss by a final of 113-55 in their last contest. Regarding personal fouls, the Tigers ended up with 22 while Illinois racked up 10 personal fouls. They made 17 of their 37 tries from three-point range. Illinois finished 66.7% from the charity stripe by converting 16 of their 24 shots. On top of that, Illinois pulled down 60 boards (21 offensive, 39 defensive), but wasn't able to put a block in the stat sheet. Illinois dished out 23 dimes and had 6 steals in the matchup. When discussing the defense, Jackson State allowed their opponent to shoot 54.8% from the floor on 40 out of 73 shooting. They also dished out 5 assists in this matchup as well as forcing the other team into 12 turnovers and having 11 steals. Pertaining to rebounding, they earned 16 with 3 of them being offensive. At the charity stripe, the Tigers knocked down 10 of 14 tries for a percentage of 71.4%. Jackson State finished having earned a 30.6% field goal percentage (19 out of 62) and converted 7 out of their 29 shots from 3-point land.
Devin Ree is one player who was a contributor in this matchup. He ended up going 63.6% from the field but finished the game without a dime. He played for 19 mins played and totaled 1 board. He scored 19 points on 7 out of 11 shooting.
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Jackson State enters this contest after finishing with a win-loss mark of 16-18 last season. They had an average of 71.4 points per game (248th in D-1) while shooting 42.2% from the floor. The Tigers hit on 32.6% from downtown (217 of 666) and 73.0% from the free throw line. As a team, Jackson State pulled down 36.6 rebounds per game and sat with 415 dimes throughout last season, which was 241st in the country in terms of passing the ball. They turned it over 13.9 times per game and as a group committed 16.5 fouls per contest.
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When they were on defense, the Tigers forced their opponents into 12.4 turnovers every game and they drew 17.1 fouls. They gave up 34.1% on 3-point shots and they were 255th in Division 1 in points per game allowed (74.6). The Tigers gave up an opponent FG percentage of 43.5% (898 of 2,063) and they surrendered 36.4 rebounds per contest as a squad. They were ranked 325th in D-1 in allowing assists 502 surrendered last season.
When they last stepped on the hardwood, the Louisville Cardinals went home victorious with a score of 104-45 when they played South Carolina State. In the matter of cleaning the glass, Louisville permitted South Carolina State to grab 29 in all (10 offensive). They shot 10.5% from behind the 3-point line by going 2 out of 19 and ended up going 17 of 22 from the free throw line (77.3%). The Cardinals allowed South Carolina State to make 13 of their 57 tries from the floor which left them shooting 22.8% for the contest. When all was said and done, the Cardinals shot 33 for 62 from the floor which gave them a percentage of 53.2%. With respect to shooting from beyond the arc, Louisville made 12 out of their 32 tries (37.5%). They were able to knock down 26 of those for a rate of 78.8%. South Carolina State committed 25 fouls for this game which took the Cardinals to the free throw line for 33 tries. They gave up possession of the ball 16 times, while getting 12 steals in the matchup. The Cardinals snagged 34 defensive rebounds and 11 offensive rebounds totaling 45 for this contest.
Khani Rooths ended up having an impact for the Cardinals in the matchup. He made 8 out of 12 for the matchup for a field goal percentage of 66.7%, and earned 7 rebounds. He earned 20 points in his 21 mins of playing time and accounted for 3 dimes for the game.
Louisville had a record of 27-8 last season. The Cardinals committed 15.6 personal fouls per contest and they hit 74.6% from the charity stripe. They earned an assist 13.9 times per contest (154th in the country) and they turned it over 11.3 times per game. Louisville earned 2,747 points over the course of last year (78.5 per contest) and they snagged 37.3 boards per contest. As an offense, the Cardinals hit 45.4% from the field, which ranked them 137th in college hoops.
The Louisville defense gave up 34.1% on three-point shots (278 of 816) and their opponents connected on 71.2% of their shots from the charity stripe. They conceded 11.8 dimes and 33.4 rebounds every game, which ranked them 63rd and 120th in college hoops. The Cardinals on the defensive end were ranked 90th in Division 1 in points allowed per contest with 69.5. They were able to force 12.8 turnovers on a nightly basis and allowed teams to shoot 42.9% from the field (123rd in college).
Who will win tonight's NCAA game against the spread?
Tony Sink's Pick: Take Jackson State
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Additional Resources:
Louisville Cardinals - Twitter
Jackson State Tigers - Twitter

