Lafayette Leopards vs Charlotte 49ers Prediction, 12/18/2025 College Basketball Picks, Best Bets & Odds
Game: Lafayette Leopards vs Charlotte 49ers
Date: Thursday, December 18, 2025
Location: Halton Arena in Charlotte, NC
TV: ESPN+
Halton Arena is where the Charlotte 49ers (4-7) will compete against the Lafayette Leopards (3-8) on Thursday.

The Lafayette Leopards faced off with Penn and went home with a loss by a final score of 74-72 in their last contest. Lafayette finished having earned a 45.8% FG percentage (27 of 59) and buried 8 out of their 21 3-point attempts. From the free throw line, the Leopards buried 10 of their 13 attempts for a rate of 76.9%. With regard to hauling in rebounds, they earned 31 with 5 of them being of the offensive variety. They also doled out 15 assists for the game as well as creating 9 turnovers and earning 5 steals. In reference to defense, Lafayette allowed the other team to shoot 42.4% from the floor on 28 out of 66 shooting. Penn distributed 18 dimes and had 6 steals for the matchup. Additionally, Penn grabbed 36 rebounds (13 offensive, 23 defensive), but couldn't earn a rejection. Penn finished 63.2% at the free throw line by burying 12 of 19 attempts. They also buried 6 of 19 shots from long range. Concerning fouls, the Leopards walked away with 16 and Penn finished the game with 15 fouls.
Caleb Williams is one player who was a contributor in this matchup. He accounted for 21 points on 8 of 16 shooting. He was on the hardwood for 37 minutes played and also collected 1 board. He finished the game shooting 50.0% from the field and dished out 2 assists.
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Lafayette will enter this contest with a win-loss mark of 3-8 so far this year. They are turning it over 12.5 times per game and as a team they are committing 16.5 fouls per game. As a unit, Lafayette is collecting 33.7 rebounds per game and is sitting with 136 assists this year, which is 287th in D-1 in terms of passing. The Leopards are connecting on 36.0% on 3-point shots (85 of 236) and 71.9% from the free throw line. They have an average of 69.5 pts per game (321st in college hoops) on 41.2% from the floor.
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When they are on the defensive end, the Leopards have forced 11.6 turnovers on a nightly basis while drawing 18.0 fouls. They are conceding 31.7% from beyond the arc and they rank 227th in D-1 in points per game from their opponents (74.9). The Leopards defense is allowing an opponent shooting percentage of 44.7% (301 of 673) and they surrender 38.3 rebounds per game as a team. They are 308th in college hoops in giving up assists to the opposition with 172 relinquished for the campaign.
The last time they took the hardwood, the Charlotte 49ers walked away from this one with a loss by a score of 74-67 when they faced Charleston. With respect to how they rebounded, Charlotte permitted Charleston to snag 29 in total (6 on the offensive side). They finished 30.0% from downtown by connecting on 6 out of 20 and ended up shooting 10 of 16 at the free throw line (62.5%). The 49ers permitted Charleston to bury 29 out of 58 attempts from the field which gave them a rate of 50.0% for the contest. At the conclusion of this game, the 49ers walked away from this one shooting 24 out of 58 from the floor which had them shooting 41.4%. In the matter of shooting from beyond the arc, Charlotte made 7 of their 29 attempts (24.1%). They were able to make 12 of the free throws for a clip of 85.7%. Charleston had 12 personal fouls in this contest which got the 49ers to the free throw line for 14 shots. They also gave up possession of the ball 9 times, while getting 10 steals in this matchup. The 49ers collected 22 defensive rebounds and 8 offensive boards totaling 30 for the contest.
Damoni Harrison ended up being a factor for the 49ers in this game. He totaled 15 points in his 26 mins on the court and tallied 3 dimes in this contest. He converted 6 of 10 for this contest giving him a field goal percentage of 60.0%, and earned 5 rebounds.
Charlotte has a win-loss mark of 4-7 on the season. On the offensive side of the court, the 49ers are hitting on 44.1% from the floor, which has them ranked 249th in the country. Charlotte has earned 768 pts on the campaign (69.8 per contest) and they collect 35.0 rebounds per game. They are earning an assist 12.5 times per game (299th in D-1) and they are losing possession via turnover 12.4 times per game. The 49ers have committed 18.5 personal fouls per game and they connect on 65.8% from the free throw line.
The Charlotte defense concedes 34.0% on shots from beyond the perimeter (81 of 238) and opponents are knocking down 65.9% of their shots from the charity stripe. They concede 12.8 dimes and 30.1 rebounds per game, which is 141st and 24th in those defensive categories. The 49ers on the defensive end are ranked 150th in the nation in PPG surrendered with 71.9. They are forcing their opponents into 10.4 turnovers on a nightly basis and allow teams to shoot 46.4% from the field (311th in Division 1).
Who will win tonight's NCAA game against the spread?
Josh Schonwald's Pick: Take Charlotte
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Additional Resources:
Charlotte 49ers - Twitter
Lafayette Leopards - Twitter

