Louisville Cardinals vs Indiana Hoosiers Prediction, 12/6/2025 College Basketball Picks, Best Bets & Odds

Game: Louisville Cardinals vs Indiana Hoosiers

Date: Saturday, December 6, 2025

Location: Gainbridge Fieldhouse in Indianapolis, IN

TV: ESPN+

The Indiana Hoosiers (7-0) will go up against the Louisville Cardinals (7-0) at Gainbridge Fieldhouse on Saturday.

The Louisville Cardinals faced Arkansas and walked away from this one with a loss by a score of 89-80 in their last game. Louisville wrapped up the game with a 41.4% field goal percentage (29 of 70) and buried 8 of their 37 three-point attempts. From the charity stripe, the Cardinals made 14 of their 18 tries for a percentage of 77.8%. In reference to grabbing rebounds, they earned 34 with 10 of them being on the offensive end. They also recorded 13 assists for the game while forcing the other team into 9 turnovers and earning 2 steals. When talking about defending, Louisville allowed the other team to shoot 41.8% from the field on 28 of 67 shooting. Arkansas earned 14 dimes and had 5 steals in this matchup. In addition, Arkansas had 38 rebounds (14 offensive, 24 defensive), but wasn't able to record a rejection. Arkansas ended up going 77.1% at the charity stripe by making 27 of their 35 attempts. They converted 6 of their 18 tries from 3-point land. In relation to personal fouls, the Cardinals ended up with 25 while Arkansas totaled 15 personal fouls.

Mikel Brown Jr. is someone who played a role for this game. He ended up scoring 22 points on 7 of 19 shooting. He played 34 mins and grabbed 5 boards. He finished 36.8% from the field and recorded 3 dimes.

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Louisville heads into this contest with a record of 7-0 so far this season. They are turning it over 10.6 times per contest and as a squad they are committing 19.1 personal fouls on a nightly basis. As a team, Louisville is pulling in 46.0 rebounds per game and is sitting with 145 dimes so far this season, which is 45th in the nation in terms of passing. The Cardinals are connecting on 37.3% on three-point shots (93 of 249) and 75.8% from the charity stripe. They have an average of 96.7 points per outing (4th in D-1) while shooting 48.1% from the floor.

On defense, the Cardinals are forcing 15.0 turnovers per contest while drawing 20.1 fouls. They are ranked 13th in the country in allowing assists with 71 relinquished this season. The Cardinals are allowing an opponent shooting percentage of 36.1% (153 of 424) and they concede 33.3 rebounds per game as a group. They are conceding 28.8% from beyond the arc and they rank 13th in college hoops in opponents points per game (63.0).

The last time they took the hardwood, the Indiana Hoosiers took a loss by a score of 73-64 against Minnesota. The Hoosiers were able to collect 17 defensive rebounds and 5 offensive boards totaling 22 for the game. They turned the ball over 7 times, while earning 7 steals for the game. Minnesota was called for 18 personal fouls in the game which got the Hoosiers to the free throw line for a total of 20 tries. They were able to knock down 12 of the free throws for a rate of 60.0%. When talking about 3-point shots, Indiana knocked down 8 out of their 27 attempts (29.6%). At the conclusion of this game, the Hoosiers finished the game shooting 22 for 55 from the field which gave them a rate of 40.0%. The Hoosiers permitted Minnesota to make 23 of their 47 attempts from the field which left them shooting 48.9% for the matchup. They shot 38.1% from beyond the perimeter by shooting 8 out of 21 and ended up going 19 out of 27 at the charity stripe (70.4%). Concerning how they attacked the glass, Indiana allowed Minnesota to pull down 36 overall (8 offensive).

Tayton Conerway ended up being a factor for the Hoosiers for the contest. He buried 6 of 11 in the game for a field goal rate of 54.5%, and tallied 2 rebounds. He racked up 18 points in his 23 mins of playing time and had 2 dimes in the matchup.

Indiana has a win-loss mark of 7-0 this season. As an offense, the Hoosiers are hitting on 50.4% from the floor, which ranks 35th in Division 1. Indiana has scored 627 points so far this year (89.6 per game) and they pull in 39.3 boards per contest. Their rate of earning assists is at 20.9 times per contest (4th in Division 1) and they are losing possession via turnover 9.7 times per game. The Hoosiers are committing 17.3 fouls per game and they go 76.8% from the charity stripe.

The Indiana defense gives up 29.5% on shots from distance (36 of 122) and their opposition makes 73.3% of their shots from the free throw line. They have conceded 9.0 dimes and 32.3 rebounds per contest, which ranks them 7th and 80th in those defensive categories. The Hoosiers are ranked 11th in D-1 in PPG given up with 62.4. They are forcing 13.4 TO's per game and have let teams shoot 36.2% from the field (9th in the country).

Who will win tonight's NCAA game against the spread?

Josh Schonwald's Pick: Take Indiana

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