Niagara Purple Eagles vs Duke Blue Devils Prediction, 11/21/2025 College Basketball Picks, Best Bets & Odds
Game: Niagara Purple Eagles vs Duke Blue Devils
Date: Friday, November 21, 2025
Location: Cameron Indoor Stadium in Durham, NC
TV: ACC Network
Cameron Indoor Stadium is the site where the Duke Blue Devils (5-0) will go up against the Niagara Purple Eagles (2-2) on Friday.

The Niagara Purple Eagles played Le Moyne and took a loss by a final of 74-68 in their last game. Niagara wrapped up the contest having earned a 40.0% field goal percentage (22 of 55) and buried 13 out of their 28 shots from 3-point land. From the free throw line, the Purple Eagles knocked down 11 of 14 attempts for a percentage of 78.6%. In relation to rebounding, they compiled 29 with 6 of them being on the offensive end. They also dished out 15 assists in this matchup in addition to forcing the other team into 13 turnovers and earning 9 steals. With respect to the defense, Niagara let their opponent shoot 43.1% from the field on 22 out of 51 shooting. Le Moyne earned 15 assists and had 3 steals in this game. Moreover, Le Moyne collected 33 rebounds (6 offensive, 27 defensive), but couldn't earn a rejection. Le Moyne ended up shooting 90.9% when shooting free throws by making 20 of 22 tries. They also converted 10 of their 24 tries from 3-point range. Regarding fouls, the Purple Eagles walked away with 17 and Le Moyne had 14 fouls.
Vice Zanki is someone who came through in this matchup. He ended up scoring 16 points on 5 of 9 shooting. He saw the court for 25 mins played and also pulled down 2 rebounds. He finished the game at 55.6% from the field and also earned 2 assists.
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Niagara will enter this contest with a win-loss mark of 2-2 on the year. They are averaging 66.5 points per outing (340th in college) while shooting 43.5% from the field. The Purple Eagles are hitting 37.8% on 3-point shots (31 of 82) and 73.6% from the charity stripe. As a unit, Niagara is pulling in 30.3 rebounds per game and has 52 dimes so far this season, which is 318th in the country in terms of passing the ball. They are turning it over 11.0 times per contest and as a team are committing 14.8 personal fouls on a nightly basis.
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On the defensive end of the court, the Purple Eagles are forcing 11.8 turnovers every game while drawing 18.0 personal fouls. They are relinquishing 36.9% on three-point shots and they are 105th in Division 1 in PPG allowed (68.3). The Purple Eagles defense is allowing a shooting percentage of 44.0% (95 of 216) and they relinquish 34.0 boards per game as a squad. They are ranked 108th in D-1 in allowing assists to their opponents with 53 surrendered so far this season.
The last time they took the hardwood, the Duke Blue Devils went home victorious with a score of 78-66 when they played Kansas. When discussing how they cleaned up the glass, Duke permitted Kansas to pull down 29 overall (8 on the offensive side). They finished shooting 19.0% from beyond the perimeter by connecting on 4 of 21 and finished the game at 10 out of 14 at the charity stripe (71.4%). The Blue Devils allowed Kansas to bury 26 out of 60 attempts from the floor which had them sitting at 43.3% for this game. When this game wrapped up, the Blue Devils ended up shooting 27 for 58 from the floor which had them sitting at 46.6%. Concerning 3-point shots, Duke made 7 out of 26 tries (26.9%). They were able to knock down 17 of the free throw tries for a percentage of 65.4%. Kansas earned 22 fouls in this contest which got the Blue Devils to the free throw line for 26 tries. They also coughed up the ball 8 times, while getting 2 steals in this matchup. The Blue Devils earned 28 defensive boards and 10 offensive boards totaling 38 for this contest.
Cameron Boozer ended up being a factor for the Blue Devils for the matchup. He earned 18 points in his 34 mins on the court and had 5 assists for the contest. He made 7 out of 17 in the game for a rate of 41.2%, and tallied 10 rebounds.
Duke has a record of 5-0 on the season. The Blue Devils are responsible for committing 17.0 personal fouls per game and they go 73.4% from the charity stripe. They are assisting teammates 20.0 times per contest (20th in college) and they are giving up possession 10.0 times per game. Duke has 462 points on the campaign (92.4 per game) and they collect 45.0 boards per game. When it comes to offensive execution, the Blue Devils are connecting on 49.7% from the field, which is 64th in college hoops.
The Blue Devils defensively are ranked 13th in Division 1 in PPG surrendered with 60.2. They are able to force 14.6 turnovers per game and allow teams to shoot 34.4% from the floor (10th in college). The Duke defense surrenders 23.8% on shots from beyond the arc (34 of 143) and their opponents are converting on 67.1% of their free throw attempts. They allow 11.4 dimes and 33.4 rebounds per contest, ranking them 93rd and 120th in D-1.
Who will win tonight's NCAA game against the spread?
Josh Schonwald's Pick: Take Niagara
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Additional Resources:
Duke Blue Devils - Twitter
Niagara Purple Eagles - Twitter

