UConn Huskies vs DePaul Blue Demons Prediction, 12/21/2025 College Basketball Picks, Best Bets & Odds
Game: UConn Huskies vs DePaul Blue Demons
Date: Sunday, December 21, 2025
Location: Wintrust Arena in Chicago, IL
TV: ESPN+
Wintrust Arena is the location where the DePaul Blue Demons (8-4) will compete against the UConn Huskies (11-1) on Sunday.

The UConn Huskies faced Butler and earned the victory with a final of 79-60 in their last contest. UConn ended the contest with a 50.8% FG percentage (32 of 63) and made 7 of their 20 three-point shots. At the charity stripe, the Huskies buried 8 of 13 attempts for a rate of 61.5%. With regard to grabbing rebounds, they compiled a total of 43 with 12 of them being of the offensive variety. They also distributed 19 assists in this contest while forcing the opposition into 10 turnovers and earning 5 steals. When discussing defending, UConn allowed their opponent to shoot 29.5% from the field on 18 of 61 shooting. Butler totaled 10 assists and had 8 steals in this game. Moreover, Butler pulled down 27 rebounds (11 offensive, 16 defensive), but didn't notch a block. Butler finished the game shooting 79.2% from the charity stripe by converting 19 of 24 attempts. They also made 5 of their 24 attempts from long range. In reference to personal fouls, the Huskies ended up walking away with 21 and Butler totaled 15 personal fouls.
Solomon Ball is one player who was a contributor in this matchup. He finished the game at 57.1% from the floor and recorded 2 dimes. He saw the court for 32 mins and also snagged 5 rebounds. He accumulated 26 points on 8 of 14 shooting.
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UConn steps onto the court with a record of 11-1 this year. They have an average of 79.0 points per outing (150th in Division 1) while hitting 49.7% from the field. The Huskies are shooting 34.5% on 3-pointers (90 of 261) and 69.4% from the charity stripe. As a unit, UConn is collecting 36.3 rebounds per contest and has accumulated 221 dimes on the campaign, which is 15th in college hoops in terms of passing the ball. They turn it over 10.4 times per contest and as a squad they are committing 18.5 personal fouls on a nightly basis.
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When they are on defense, the Huskies are forcing their opponents into 13.1 turnovers per contest while drawing 16.8 fouls. They surrender 26.4% on 3-pointers and they are 7th in the country in PPG allowed (61.7). The Huskies defensively are giving up an opponent shooting percentage of 37.2% (240 of 646) and they relinquish 31.2 rebounds per game as a group. They are currently ranked 6th in college hoops in allowing assists with 99 surrendered so far this year.
When they last stepped on the court, the DePaul Blue Demons took a loss by a score of 79-66 when they faced St. John's. In reference to cleaning up the glass, DePaul permitted St. John's to snag 37 in total (8 on the offensive glass). They shot 45.5% from 3-point land by going 10 of 22 and ended up going 17 out of 21 from the free throw line (81.0%). The Blue Demons permitted St. John's to bury 26 of 58 attempts from the floor which gave them a shooting percentage of 44.8% in the game. Overall, the Blue Demons finished the game shooting 27 for 69 from the floor which had them shooting 39.1%. With regard to 3-pointers, DePaul made 7 of 25 tries (28.0%). They were able to make 5 of the free throw tries for a rate of 100.0%. St. John's earned 10 personal fouls in the game which got the Blue Demons to the charity stripe for 5 tries. They also coughed up the ball 10 times, while getting 7 steals for this contest. The Blue Demons corralled 22 defensive boards and 9 offensive rebounds totaling 31 in this game.
Kaleb Banks was important for the Blue Demons for the contest. He made 8 out of 16 for the game for a field goal rate of 50.0%, and had 10 rebounds. He tallied 19 points in his 35 mins on the hardwood, but wrapped up this contest with no dimes.
DePaul has a record of 8-4 so far this season. When it comes to offense, the Blue Demons are shooting 45.4% from the field, which ranks them 188th in the country. DePaul has tallied 917 points on the campaign (76.4 per contest) and they collect 33.8 boards per game. They are assisting teammates 17.0 times per game (66th in Division 1) and they are giving up possession 11.9 times per game. The Blue Demons are committing 18.2 fouls per contest and they go 70.5% from the free throw line.
The DePaul defense gives up 33.6% on shots from distance (73 of 217) and their opposition knocks down 70.4% of their shots from the free throw line. They have conceded 13.5 dimes and 34.5 boards per game, which is ranked 197th and 172nd in college hoops. The Blue Demons defensively are ranked 86th in the nation in points allowed per contest with 68.8. They are forcing their opponents into 14.1 TO's per game and allow teams to shoot 42.4% from the floor (133rd in D-1).
Who will win tonight's NCAA game against the spread?
Tony Sink's Pick: Take UConn
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