Saint Louis Billikens vs Michigan Wolverines Prediction, 3/21/2026 College Basketball Picks, Best Bets & Odds

Game: Saint Louis Billikens vs Michigan Wolverines

Date: Saturday, March 21, 2026

Location: KeyBank Center in Buffalo, NY

TV: CBS

Odds/Point Spread: Saint Louis (+13)

The Michigan Wolverines (31-3) will play the Saint Louis Billikens (28-5) at KeyBank Center on Saturday in the round of 32 of the NCAA Tournament. Saint Louis opens this matchup as 13-point underdogs. The over/under is 161.5.

The Saint Louis Billikens took the court against Georgia and took home the win by a score of 102-77 in their last contest. Saint Louis wrapped up the contest with a 58.3% FG percentage (42 of 72) and made 9 out of their 28 shots from beyond the arc. From the charity stripe, the Billikens knocked down 9 of 11 shots for a percentage of 81.8%. In regard to grabbing rebounds, they earned 44 with 10 of them being on the offensive end. They also dished out 27 dimes for this contest in addition to forcing 11 turnovers and getting 8 steals. When it comes to defense, Saint Louis allowed the other team to go 34.7% from the floor on 25 of 72 shooting. Georgia doled out 9 dimes and had 9 steals for the game. On top of that, Georgia grabbed 30 rebounds (11 offensive, 19 defensive), but didn't notch a block. Georgia ended up going 65.4% at the free throw line by making 17 of their 26 attempts. They buried 10 of 39 shots from long range. When discussing personal fouls, the Billikens finished with 20 while Georgia recorded 14 personal fouls.

Dion Brown is someone who came through for this game. He finished the contest at 90.0% from the field and earned 4 assists. He played for 22 minutes played and totaled 4 rebounds. He recorded 18 points on 9 out of 10 shooting.

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Saint Louis enters this game with a win-loss record of 28-5 for the season. They are turning it over 12.5 times per game and as a unit they commit 18.3 fouls on a nightly basis. As a unit, Saint Louis is pulling down 39.9 boards per game and has earned 605 dimes for the campaign, which is 8th in college hoops in terms of passing the rock. The Billikens are shooting 40.1% on 3-point shots (360 of 898) and 74.4% from the charity stripe. They currently have an average of 87.2 points per game (10th in college) while hitting 50.9% from the field.

Defensively, the Billikens are able to force 11.7 turnovers per game and they draw 16.5 personal fouls. They are 67th in D-1 in allowing assists to the opposition with 389 surrendered for the campaign. The Billikens defensively are giving up an opponent shooting percentage of 37.9% (756 of 1,997) and they relinquish 32.4 rebounds per contest as a team. They relinquish 29.4% on shots from beyond the perimeter and they are 63rd in the nation in PPG from their opponents (69.5).

In their last game, the Michigan Wolverines walked away with a victory by a final of 101-80 against Howard. The Wolverines were able to pull down 30 defensive boards and 4 offensive rebounds totaling 34 for the contest. They also turned it over 10 times, while recording 4 steals in the matchup. Howard committed 15 fouls in this matchup which got the Wolverines to the free throw line for a total of 20 shots. They were able to knock down 16 of them for a percentage of 80.0%. In relation to shots from downtown, Michigan made 11 out of 24 attempts (45.8%). Overall, the Wolverines went 37 for 55 from the floor which gave them a shooting percentage of 67.3%. The Wolverines allowed Howard to make 27 of 63 attempts from the floor which gave them a rate of 42.9% in this game. They went 48.3% from distance via 14 of 29 and finished the game at 12 of 17 at the charity stripe (70.6%). When discussing cleaning the glass, Michigan allowed Howard to snag 21 overall (6 on the offensive side).

Morez Johnson Jr. ended up being a factor for the Wolverines for this contest. He made 8 of 8 for this contest for a field goal percentage of 100.0%, and had 10 rebounds. He earned 21 points in his 26 mins on the court, but didn't record an assist.

Michigan has a mark of 31-3 on the year. When it comes to offense, the Wolverines are connecting on 50.5% from the floor, which ranks them 8th in Division 1. Michigan has tallied 2,952 pts on the season (86.8 per contest) and they grab 40.0 rebounds per game. They are assisting teammates 18.5 times per contest (5th in the nation) and they lose possession via turnover 12.0 times per game. The Wolverines are responsible for committing 15.6 personal fouls per contest and they connect on 74.7% from the free throw line.

The Wolverines on the defensive end are ranked 57th in college hoops in points allowed per contest with 69.2. They are able to force 11.1 turnovers on a nightly basis and allow teams to shoot 38.4% from the floor (3rd in the nation). The Michigan defense gives up 30.2% on 3-pointers (272 of 901) and their opponents are knocking down 75.1% of their free throw shots. They have surrendered 11.4 dimes and 31.2 boards on a nightly basis, ranking them 35th and 27th in those defensive categories.

Who will win tonight's NCAA game against the spread?

Tony Sink's Pick: Take Saint Louis (+13)

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