Wyoming Cowboys vs Grand Canyon Lopes Prediction, 2/21/2026 College Basketball Picks, Best Bets & Odds

Game: Wyoming Cowboys vs Grand Canyon Lopes

Date: Saturday, February 21, 2026

Location: Global Credit Union Arena in Phoenix, AZ

TV: ESPN+

Global Credit Union Arena is the site where the Grand Canyon Lopes (17-9) will take on the Wyoming Cowboys (14-12) on Saturday.

The Wyoming Cowboys faced Fresno State and took home the win by a score of 92-82 in their last contest. Wyoming wrapped up the contest having earned a 54.0% FG percentage (34 of 63) and made 15 of 33 3-pointers. From the free throw line, the Cowboys converted 9 of 11 shots for a percentage of 81.8%. When talking about rebounding, they earned 32 with 12 of them being on the offensive end. They also recorded 21 assists in this matchup in addition to creating 8 turnovers and having 5 steals. Pertaining to the defense, Wyoming let their opponent shoot 51.8% from the field on 29 of 56 shooting. Fresno State earned 15 assists and had 6 steals in this game. Additionally, Fresno State grabbed 26 boards (9 offensive, 17 defensive), but wasn't able to record a block. Fresno State finished the game shooting 70.8% from the charity stripe by making 17 of their 24 attempts. They also converted 7 out of their 15 attempts from distance. In relation to fouls, the Cowboys left the arena with 22 while Fresno State racked up 15 fouls.

Nasir Meyer is a guy who played a role for this contest. He finished the contest at 53.3% from the floor and distributed 4 assists. He was on the hardwood for 31 minutes played and also grabbed 5 boards. He totaled 22 points on 8 of 15 shooting.

Get all of our NCAA Betting Picks

Wyoming comes into this contest with a mark of 14-12 on the campaign. They have an average of 78.0 pts per game (136th in Division 1) while hitting 45.5% from the field. The Cowboys are hitting 33.7% on shots from distance (219 of 650) and 74.3% from the charity stripe. As a unit, Wyoming is pulling in 35.9 boards per game and is sitting with 368 dimes for the campaign, which is 196th in the nation in terms of passing the rock. They lose possession by turning the ball over 11.5 times per contest and as a unit they commit 21.3 personal fouls per contest.

On defense, the Cowboys are forcing their opponents into 11.4 turnovers per contest and they draw 18.6 fouls. They are 33rd in the nation in giving up assists with 293 conceded on the campaign. The Cowboys defense is giving up an opponent shooting percentage of 45.8% (634 of 1,384) and they relinquish 30.9 rebounds per game as a team. They are relinquishing 32.8% on 3-point attempts and they rank 174th in D-1 in PPG allowed (73.5).

The last time they took the court, the Grand Canyon Lopes walked away with a victory by a final of 73-63 against San Diego State. In relation to team rebounding, Grand Canyon allowed San Diego State to collect 30 in total (11 offensive). They shot 20.0% from behind the 3-point line by going 3 of 15 and ended up going 16 of 18 from the free throw line (88.9%). The Lopes allowed San Diego State to knock down 22 out of 62 tries from the field which had them shooting 35.5% for this game. When this game wrapped up, the Lopes shot 24 for 56 from the field which gave them a shooting percentage of 42.9%. In reference to 3-point shots, Grand Canyon knocked down 7 of 19 tries (36.8%). They were able to convert 18 of the free throws for a clip of 78.3%. San Diego State had 19 personal fouls for this game which got the Lopes to the free throw line for 23 tries. They turned the ball over 10 times, while getting 8 steals for this game. The Lopes pulled down 25 defensive boards and 9 offensive rebounds totaling 34 for the matchup.

Jaden Henley was important for the Lopes in this contest. He converted 7 out of 17 for this game giving him a field goal percentage of 41.2%, and earned 3 rebounds. He tallied 21 points in his 35 minutes of playing time and accounted for 2 dimes for the game.

Grand Canyon has a win-loss mark of 17-9 this year. The Lopes commit 18.1 fouls per contest and they go 75.6% from the charity stripe. They are assisting teammates 12.6 times per contest (286th in the country) and they turn it over 12.2 times per game. Grand Canyon has accounted for 1,955 points so far this year (75.2 per game) and they pull in 36.4 rebounds per contest. When it comes to offense, the Lopes are hitting on 44.8% from the floor, which has them ranked 209th in the nation.

The Grand Canyon defense gives up 31.8% on shots from beyond the arc (178 of 560) and opponents are making 74.5% of their foul shots. They relinquish 11.6 assists and 31.8 total rebounds per game, which ranks them 46th and 46th in D-1. The Lopes are ranked 53rd in Division 1 in PPG surrendered with 68.5. They are able to force 12.4 TO's per game and allow teams to shoot 41.1% from the field (44th in college).

Who will win tonight's NCAA game against the spread?

Josh Schonwald's Pick: Take Wyoming

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get college basketball picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.