Inter Milan vs Sassuolo Prediction, 9/21/2025 Soccer Pick, Tips and Odds

by Guy Bruhn - 9/17/2025

Game: Inter Milan vs Sassuolo

Date: Sunday, September 21, 2025

Location: Stadio Giuseppe Meazza in Milan, Italy

TV: Paramount+

Inter Milan (1-0-2) hosts Sassuolo (0-0-2) at Stadio Giuseppe Meazza in Milan, Italy on Sunday. Inter Milan are priced at -275 while Sassuolo are at +220. The total is set at 3. The goalkeepers protecting the net will be Yann Sommer for Inter Milan and Arijanet Muric for Sassuolo.

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Internazionale has accounted for 7 SVs and also have earned a save% of 53.8% for the season. Their goal differential is at 3 with the help of 9 goals put in the net in addition to 6 goals conceded. On the campaign, the club has put together an average of 1.00 pts per fixture (3 points) and also are ranked 1st in European soccer with 8 assists. The Black and Blues rank 5th in the category of xG with 4.3, and the squad's expected goals against are sitting at 2.7. Inter Milan has a total of 2 yellow card warnings this year. Inter has allowed 6 goals while relinquishing 2.00 goals per 90 minutes, and the opposition have earned 13 SoT on them. They have earned 1 clean sheet, which has them at a percentage of 33.3% so far this year.

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The Black and Greens average 0.0 pts/match while compiling 2 assists and 1 red card. U.S. Sassuolo Calcio has accumulated a clean sheet percentage of 50.0% this year and 11 yellow cards. Sassuolo has a ranking of 16th in relation to goals conceded having 5, and the team's difference in goals is sitting at -3. Over the course of the season, U.S. Sassuolo Calcio has a save percentage of 61.5% (13 SoT against), and also rank 20th among Big 5 teams with 0 points. The club's goals against per 90 min is 2.50 with 8 saves, and they are sitting with 1 clean sheet. Sassuolo has amassed 2 goals and the team's expected goals this year is currently at 2.8.

The man defending the goal for Inter is Yann Sommer. Sommer has been on the field for 32,337 mins and has earned 1,116 saves in his career. Sommer (181-81-99 mark in his professional soccer career) has accumulated 108 clean sheets, which has earned him a 30.1%% shutout rate. The keeper hailing from Switzerland has faced 1,573 shots attempted against him in 361 starting assignments. His goals allowed per 90 mins is 1.27 (455 total goals allowed) and he holds a save % of 70.9%.

Arijanet Muric is expected to look after the net for Sassuolo. So far in his career, Muric has conceded 52 goals and has tallied 135 stops in 30 starts. He has earned a save % of 72.2% and his shutout rate is currently at 6.7%%. He has allowed 1.73 goals per 90 minutes while he holds a mark of 5-10-15. Muric has racked up 2 shutouts and has seen 187 shots against him in 2,700 mins throughout his career.

Marcus Thuram is one footballer you are going to want to keep your eye on for Inter. He has totaled 33 assists while earning 193 points during his career. The forward born in France has 80 goals in 19,544 mins. Thuram has been in the starting lineup in 222 matchups so far in his career while he scores 0.37 goals per 90 minutes.

Sassuolo has a guy in Andrea Pinamonti, who pesters opposing defenses. The forward born in Italy has been on the field for 12,897 mins while scoring 44 goals. He sports an average of 0.31 goals per 90 minutes and has started 144 matches in his career. He has accounted for 95 pts thus far in his career and has assisted a teammate on a goal 7 times.

Who will win tonight's soccer game against the spread?

Guy Bruhn's Pick: Take Inter Milan (+220)

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Inter Milan vs Sassuolo Prediction, 9/21/2025 Soccer Pick, Tips and Odds

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