Napoli vs Pisa Prediction, 9/22/2025 Soccer Pick, Tips and Odds

by Josh Schonwald - 9/18/2025

Game: Napoli vs Pisa

Date: Monday, September 22, 2025

Location: Stadio Diego Armando Maradona in Naples, Italy

TV: Paramount+

Napoli (3-0-0) are welcoming Pisa (0-1-1) at Stadio Diego Armando Maradona in Naples, Italy on Monday. The Blues are priced at -150 and the Black and Blues are at +125. The over/under is 3. The men protecting the net will be Vanja Milinkovic-Savic for Napoli and Adrian Semper for Pisa.

soccer picks Alex Meret Napoli predictions best bet odds

S.S.C. Napoli has surrendered 1 goal while relinquishing 0.33 goals per 90 min, and their oppositition are sitting with 6 SoT against them. They have recorded 2 clean sheets, which gives them a rate of 66.7% for the year. Napoli has recorded 3 yellow card warnings this year. The Blues sit at 1st in the matter of goals expected having 5.5, and their xGA sit at 2.4. So far this season, the club is sitting with an average of 3.00 pts per contest (9 pts) and they also sit at 5th in European soccer with 4 assists. Their differential on goals is currently at 5 by 6 goals accumulated as well as 1 goal given up. Napoli has tallied 5 SVs and also have a SV rate of 83.3% on the season.

Get all of our Soccer Betting Picks

This season, the Black and Blues have a save percentage of 85.7% (14 shots on target against), and are ranked 17th among Big 5 teams with 1 point. The Black and Blues are averaging 0.5 pts per contest while tallying 0 assists. Pisa has earned 1 goal and their goals expected on the year is sitting at 1.7. The Black and Blues have earned 3 yellow card warnings. Their goals against per 90 minutes is currently at 1.00 in addition to 11 saves. Pisa ranks 11th in the category of goals conceded having 2, and their goal difference is sitting at -1.

The man protecting the net for Napoli is Vanja Milinkovic-Savic. Savic has been on the pitch for 13,214 minutes and has accumulated 402 stops in his career. The goalkeeper hailing from Serbia has had 564 shots attempted against him in 147 career starting assignments. His goals allowed per 90 minutes is 1.08 (159 goals surrendered) and he holds a save % of 71.3%. Savic (51-48-48 mark during his career) has accounted for 44 shutouts, which gives him a 30.0%% shutout percentage.

Adrian Semper will be residing in front of the goal for Pisa. During his pro soccer career, Semper has allowed 12 goals and has accounted for 38 stops in 10 starts. He has earned a save % of 76.0% and his shutout rate is currently at 20.0%%. He has given up 1.20 goals per 90 and he has a mark of 1-4-5. Semper has accumulated 2 clean sheets while defending 50 shots attempted against him in 900 career minutes.

Kevin De Bruyne is a member of the squad who can make a noticable difference for Napoli. De Bruyne has had a starting assignment in 516 contests during his soccer career and accounts for 0.30 goals per 90 minutes. The midfielder representing Belgium has earned 149 goals scored in 44,788 professional minutes played. He has 227 assists while tallying 525 pts so far in his career.

Pisa features a game changer in Daniel Denoon, who gives opposing coaches headaches. The defender from Switzerland has been on the field for 77 minutes and has earned 0 goals. He sports an average of 0.00 goals per 90 mins and has been a starter in 1 games in his career. He has totaled 0 points during his pro soccer career and has assisted a teammate on a goal 0 times.

Who will win tonight's soccer game ATS?

Josh Schonwald's Pick: Take Pisa (-150)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get all of Today's Free Soccer Picks

Get all of Today's Expert Soccer Picks

Start:	September 19, 2025 @ 11:00 PM
Expert:	Griffin Murphy
Free $60 Account Sign Up

Napoli vs Pisa Prediction, 9/22/2025 Soccer Pick, Tips and Odds

Most Recent Soccer Picks