Arizona Diamondbacks vs Cincinnati Reds Prediction, 6/6/2025 MLB Picks, Best Bets & Odds
Game: Arizona Diamondbacks vs Cincinnati Reds
Date: Friday, June 6, 2025
Location: Great American Ball Park in Cincinnati, OH
TV: FanDuel Sports Network Ohio
Odds/Point Spread: Arizona (-152) Cincinnati (+126)
The Arizona Diamondbacks (30-31) are en route to Great American Ball Park on Friday where they will go up against the Cincinnati Reds (30-33). The moneyline on this contest has Arizona at -152 while Cincinnati is priced at +126. The over/under is 9. The pitchers who are expected to start are Eduardo Rodriguez and Nick Lodolo.


As a team, the Arizona Diamondbacks are recording 5.0 runs per game, which ranks them 4th in baseball. They have notched a total of 306 runs while holding a team OBP of .332. The Diamondbacks have tallied 118 doubles as a team and have hit 84 balls out of the stadium. They have accumulated 299 runs batted in in addition to 525 base knocks this season, while their average at the plate comes in at .254. Arizona has a slugging % of .444 and have struck out 458 times, while being walked on 223 occasions.
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The Diamondbacks have an ERA of 4.68 this season (24th in the league), and their staff has struck out 520 batters. Diamondbacks pitchers have allowed 75 home runs in addition to 310 runs in total (24th in the league). Their pitching staff has walked 204 opposing batters and their FIP sits at 4.24 as a squad this season. Arizona has given up 514 base hits (8.5 per 9 innings) and 283 earned runs. Their strikeout to walk ratio sits at 2.55 and the pitching staff has earned a collective WHIP of 1.32.
The Diamondbacks bullpen have accumulated a save rate of 63.3% and have stepped onto the mound in 65 save situations. The bullpen pitchers have inherited 63 runners for the season with 34.9% of those runners crossed home plate. Diamondbacks relief pitchers have come into the game with runners on base 50 times as well as having 59 appearances in high leverage situations. The Diamondbacks have dispatched 187 relief pitchers to the mound for the year. The relief pitchers have recorded 33 holds on the year (18th in the league). They have accumulated 19 saves over the course of the season and have blown 11 out of their 30 save chances.
The Arizona Diamondbacks have 1,631 putouts at this point in the season, as well as 550 assists and 31 errors. Their fielding percentage is currently at .986 which puts them in 16th in professional baseball, and have accumulated 41 double plays. The Diamondbacks have transformed 69.6% of baseballs in play into outs out of their 4,893 innings on the diamond, which has them ranked 19th in pro baseball.
Rodriguez has taken the mound for 1,194 frames and has earned 1,206 K's in his pro baseball career. His earned run average is 4.19 (556 ER's allowed) and his WHIP is 1.317. He has given up 1,160 hits (8.7 hits per 9 innings) and has had 413 walks. Rodriguez (86-60 career record) has a FIP of 4.13 while going up against 5,096 opposing batters in the majors.
The Cincinnati Reds have tallied a team on-base percentage of .318 and a batting average of .243 on the season. They have been rung up on 560 occasions (5th in baseball) and have earned 513 base hits. Cincinnati has tallied 64 home runs for the year as well as 268 runs batted in. The Reds hold a team SLG% of .391 and they earn 4.44 runs per game (10th in baseball). They have tallied 107 doubles, while getting a free base 218 times and recording 280 runs.
The Reds have a WHIP of 1.203 with a FIP of 4.08 as a staff so far this season. They are sitting at 12th in baseball as a pitching staff in total hits relinquished with 481. The Cincinnati pitching staff have allowed 257 runs on the year while holding an ERA of 3.80 (235 earned runs yielded). Their K/BB ratio sits at 8.10 (501 strikeouts vs 189 free passes). They have conceded 71 dingers and they concede 4.15 runs per 9 innings (13th in baseball).
Cincinnati relief pitchers have an inherited score percentage of 31.4% out of their 70 inherited runners. Their relief pitchers have taken the field 56 times in high leverage situations and on 43 occasions with runners on. With 69 save situations, the Reds have accumulated 42 holds in addition to 8 blown saves. They sit at 9th in the league with a save percentage of 68.0%, and they have dispatched 211 relievers to the hill so far this season. Cincinnati has called on relievers to take the mound in 25 save opportunities and they have come away with 17 saves.
The Cincinnati Reds have turned 35 double plays and hold a fielding percentage of .986 (15th in pro baseball). The Reds have racked up 483 assists, 30 errors and are sitting with 1,671 putouts this year. Out of their 5,013 innings played, the Reds have a defensive efficiency of 72.2% (3rd in the majors).
So far in his career, Lodolo has conceded 304 base knocks while tallying 360 punch outs in 322 innings. Lodolo (19-18 mark in his career) has a 4.22 earned run average while giving up 8.5 hits per 9 innings. He has surrendered a total of 151 earned runs while earning a WHIP of 1.254 and being the owner of a FIP of 4.2. He has a K/BB ratio of 3.60 and he has faced 1,390 batters during his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Cincinnati (+126)
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Additional Resources:
Cincinnati Reds - Twitter
Arizona Diamondbacks - Twitter