Arizona Diamondbacks vs Milwaukee Brewers Prediction, 8/27/2025 MLB Picks, Best Bets & Odds

Game: Arizona Diamondbacks vs Milwaukee Brewers

Date: Wednesday, August 27, 2025

Location: American Family Field in Milwaukee, WI

TV: FanDuel Sports Network Wisconsin

Odds/Point Spread: Arizona (+120) Milwaukee (-144)

The Milwaukee Brewers (82-50) will try to defeat the Arizona Diamondbacks (64-68) at American Family Field on Wednesday. The moneyline on this matchup has the Diamondbacks at +120 and the Brewers are coming in at -144. The over/under has been set at 8.5. The men taking the mound will be Ryne Nelson and Quinn Priester.

Arizona owns a slugging percentage of .438 and have been rung up 1,062 times, while drawing a walk on 448 occasions. They have accumulated 635 runs batted in in addition to 1,116 hits so far this season, and their average at the plate comes in at .250. The Diamondbacks have accumulated 225 doubles as a team and have hit 183 baseballs out of the stadium. They have earned 650 runs scored and hold an on-base percentage of .324. As a squad, the Arizona Diamondbacks are scoring 4.9 runs per contest, which has them at 6th in MLB.

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The Diamondbacks have a team earned run average of 4.54 so far this season (25th in the league), and the staff has struck out 1,054 batters. Diamondbacks pitchers have conceded 160 home runs in addition to 642 total runs (25th in the league). Their pitching staff has walked 411 batters and their FIP sits at 4.28 as a team so far this season. Arizona has allowed 1,151 hits (8.8 per 9 innings) in addition to 593 earned runs. Their strikeout to walk ratio is 2.56 and the pitching staff sits with a WHIP of 1.33.

The Diamondbacks have dispatched 401 relievers to the mound this season. The bullpen pitchers have inherited 145 base runners on the year with 31.0% of those players crossed the plate. They have 35 saves this season and have blown 25 of their 60 save chances. The Diamondbacks bullpen have compiled a save rate of 58.3% and stepped onto the hill in 129 save situations. The relievers have a total of 65 holds so far this season (22nd in MLB). Diamondbacks pitchers have entered the game with runners on 113 times and also have had 127 appearances in high leverage situations.

The Diamondbacks have converted 69.3% of balls hit into play into outs out of 10,575 innings, which ranks them 21st in MLB. The Arizona Diamondbacks have 3,525 putouts on the campaign, as well as 1,178 assists and 65 errors. Their fielding percentage is currently at .986 which puts them in 16th in the majors, and they have turned 102 double plays.

Nelson has taken the hill for 432 innings and has 343 strikeouts in his career. His ERA is 4.31 (207 earned runs allowed) and he has a WHIP of 1.241. He has given up 418 hits (8.7 hits per 9 innings) and has had 118 free passes. Nelson (25-18 mark in his career) sits with a FIP of 4.25 while he has faced 1,800 batters in the major leagues.

The Brewers hold a slugging % of .404 and they average 5.10 runs per game (3rd in MLB). They have 210 doubles, while getting a free base 459 times as well as putting up 673 runs. Milwaukee has knocked in 140 HRs this year as well as 625 RBIs. They have been called out on strikes on 1,033 occasions (25th in baseball) and have recorded 1,152 hits. The Milwaukee Brewers are sitting with a team on-base percentage of .332 as well as a batting average of .257 on the year.

The Milwaukee pitching staff have conceded 512 runs so far this year while holding an ERA of 3.58 (468 earned runs surrendered). They have conceded 143 homers and they surrender 3.92 runs per 9 innings (3rd in baseball). The Brewers hold a team WHIP of 1.228 with a FIP of 3.98 as a unit on the campaign. They currently have a strikeout to walk ratio of 8.90 (1,157 strikeouts vs 441 free passes). They are sitting at 3rd in the league as a staff in total hits given up with 1,002.

Milwaukee relief pitchers hold an inherited score percentage of 31.6% of 174 inherited runners. Their relief pitchers have come in 155 times in high leverage situations and on 116 occasions with runners on. With 153 save situations, the Brewers have compiled 94 holds in addition to 17 blown saves. They are currently ranked 5th in MLB holding a save percentage of 69.1%, and they have dispatched 449 relievers to the mound so far this year. Milwaukee has called on relievers to step onto the mound in 55 save opportunities and they have tallied 38 saves.

Out of their 10,581 innings on the field, the Brewers are sitting with a defensive efficiency of 71.4% (4th in baseball). The Milwaukee Brewers have gotten 92 double plays and own a fielding percentage of .987 (10th in professional baseball). The Brewers have accrued 1,055 assists, 60 errors and have accumulated 3,527 putouts this year.

Priester (17-11 career record) has earned a 4.67 earned run average and has given up 9.1 hits per 9 innings. He has a strikeout to walk ratio of 2.01 and he has gone up against 991 opposing hitters in his career. He has allowed 118 ER's while earning a WHIP of 1.395 and having a FIP of 4.6. During his pro baseball career, Priester has allowed 231 base knocks while he has earned 173 strikeouts in 227 frames.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Milwaukee (-144) and under 8.5 runs

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