Arizona Diamondbacks vs Minnesota Twins Prediction, 9/13/2025 MLB Picks, Best Bets & Odds

Game: Arizona Diamondbacks vs Minnesota Twins

Date: Saturday, September 13, 2025

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: Arizona (-196) Minnesota (+162)

Target Field is where the Minnesota Twins (64-82) will attempt to defeat the Arizona Diamondbacks (73-74) on Saturday. The odds on this game have the Diamondbacks at -196 and the Twins open at +162. The over/under is 8.5. The pitchers who are expected to start are Ryne Nelson and Joe Ryan.

Arizona has a slugging percentage of .434 and have been rung up 1,190 times, while taking a walk on 490 occasions. They have accumulated 705 runs batted in in addition to 1,242 base knocks this season, while their batting average sits at .250. The Diamondbacks have earned 246 two-baggers as a unit and have hit 199 balls out of the park. They have earned a total of 724 runs scored while holding a team OBP of .323. As a squad, the Arizona Diamondbacks are notching 4.9 runs per outing, which is 6th in baseball.

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The Diamondbacks have compiled a team earned run average of 4.47 for the season (23rd in MLB), and the staff has struck out 1,163 hitters. Diamondbacks pitchers have yielded 174 home runs and also 705 total runs (24th in baseball). Their pitching staff has walked 455 opposing batters and their FIP comes in at 4.26 as a unit so far this year. Arizona has conceded 1,271 hits (8.8 per 9 innings) and 650 earned runs. They have accrued a K/BB ratio of 2.56 and their pitching staff has a team WHIP of 1.32.

The Diamondbacks have sent 447 relievers to the hill this year. The relief pitchers have inherited 173 base runners for the season and 34.1% of them crossed home plate. They have recorded 40 saves for the season and have blown 27 out of their 67 chances to get a save. The Diamondbacks bullpen have recorded a save percentage of 59.7% and have stepped onto the mound in 152 save situations. The relievers have earned 81 holds for the season (15th in MLB). Diamondbacks bullpen pitchers have stepped onto the hill with runners on base 132 times in addition to having 145 appearances in high leverage situations.

The Diamondbacks have converted 69.5% of balls hit into play into outs in their 11,769 innings on the field, ranking them 20th in professional baseball. The Arizona Diamondbacks have amassed 3,923 putouts on the campaign, in addition to 1,328 assists and 73 errors. Their fielding rate is currently at .986 which is 15th in pro baseball, and have earned 116 double plays.

Nelson has thrown 450 innings and has 356 punch outs in his MLB career. Nelson (26-18 career mark) has earned a FIP of 4.18 while he has faced 1,867 batters in the major leagues. His earned run average is 4.24 (212 earned runs allowed) and his WHIP is 1.229. He has allowed 431 hits (8.6 hits per nine innings) and has 122 free passes.

The Twins hold a team SLG% of .398 and they are recording 4.23 runs per outing (23rd in baseball). They have notched 223 two-baggers, while taking a walk 453 times as well as scoring 617 runs. Minnesota has accounted for 173 home runs so far this year to go along with 585 RBIs. They have been called out on strikes on 1,217 occasions (16th in the league) and have notched a total of 1,169 hits. The Minnesota Twins have accumulated an on-base percentage of .312 as well as a batting average of .239 for the year.

The Minnesota pitching staff have given up 702 runs for the season while having an ERA of 4.60 (656 earned runs allowed). They have surrendered 176 dingers and they concede 4.92 runs per 9 innings (24th in MLB). The Twins hold a team WHIP of 1.330 with a FIP of 4.14 as a team on the year. Their K/BB ratio is 8.60 (1,221 strikeouts against 415 walks). They come in at 26th in the league as a staff in total hits allowed with 1,291.

Sitting with 139 save situations, the Twins have accumulated 87 holds in addition to 23 blown saves. Minnesota has had relief pitchers step onto the mound in 50 save chances and they have recorded 27 saves. Their relievers have stepped onto the hill 162 times in high leverage situations and on 110 occasions with runners on base. Minnesota relievers have an inherited score percentage of 36.3% of 160 inherited base runners. They sit at 27th in MLB holding a save rate of 54.0%, and they have sent 492 relievers to the mound so far this season.

In 11,547 innings on the diamond, the Twins are sitting with a efficiency on defense of 68.2% (29th in professional baseball). The Minnesota Twins have gotten 89 double plays and have a fielding percentage of .985 (18th in professional baseball). The Twins have racked up 1,092 assists, 75 errors and have a tally of 3,849 putouts so far this year.

So far in his pro baseball career, Ryan has surrendered 520 base hits while he has accumulated 701 K's in 627 frames. He has surrendered 263 ER's while earning a WHIP of 1.057 and a FIP of 3.7. He has a strikeout to walk ratio of 4.90 and he has faced 2,542 opposing hitters in his pro baseball career. Ryan (46-34 win-loss record in his career) holds a 3.77 ERA while giving up 7.5 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Arizona (-196)

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