Baltimore Orioles vs New York Yankees Prediction, 9/28/2025 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs New York Yankees

Date: Sunday, September 28, 2025

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: Baltimore (+106) New York (-128)

The New York Yankees (91-68) will try to beat the Baltimore Orioles (75-84) at Yankee Stadium on Sunday. The line on this matchup has the Orioles at +106 and the Yankees are opening at -128. The over/under is set at 8. The starting pitchers are Kyle Bradish and Luis Gil.

Baltimore owns a slugging percentage of .395 and have been called out on strikes 1,426 times, while drawing a walk on 473 occasions. They have accrued 636 runs batted in as well as 1,258 hits on the year, while their team batting average is at .236. The Orioles have tallied 249 doubles as a unit and have hit 186 balls out of the park. They have notched a total of 670 runs scored and hold an OBP of .305. As a unit, the Baltimore Orioles are putting up 4.2 runs per game, which puts them at 23rd in MLB.

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They have a strikeout to walk ratio of 2.59 and their pitching staff holds a WHIP of 1.37. Orioles pitchers have allowed 209 home runs and also 771 runs in total (25th in the league). Baltimore has allowed 1,411 base knocks (9.0 per 9 innings) and 716 earned runs. The Orioles hold a team earned run average of 4.57 on the year (24th in MLB), and their staff has struck out 1,325 batters. They have walked 512 opposing batters and their FIP sits at 4.38 as a team this year.

Orioles relief pitchers have entered the contest with opponents on base 152 times in addition to having 168 appearances in high leverage situations. The relievers have earned 105 holds on the year (4th in the league). The Orioles bullpen have a save percentage of 65.5% and have stepped onto the mound in 167 save situations. They have compiled 38 saves on the season and have not converted 20 of 58 save opportunities. The bullpen pitchers have inherited 211 base runners on the year with 27.0% of them ended up scoring. The Orioles have sent 533 relief pitchers to the mound for the year.

The Orioles have transformed 68.4% of balls hit into play into outs out of their 12,678 innings on the field, which ranks them 27th in professional baseball. The Atlanta Braves have earned 4,226 putouts for the season, as well as 1,386 assists and 87 errors. Their fielding rate is at .985 which has them ranked 20th in baseball, and have a total of 120 double plays.

Bradish has pitched in 353 innings and is sitting with 371 K's during his career. His earned run average is 3.47 (136 earned runs allowed) and he has a career WHIP of 1.164. He has conceded 296 hits (7.5 hits per 9 innings) with 115 free passes. Bradish (19-15 win-loss record in his career) holds a FIP of 3.41 and he has faced 1,452 hitters in the majors.

The Yankees have a team SLG% of .454 and they are earning 5.23 runs per outing (1st in MLB). They have tallied 255 two-baggers, while walking 628 times and earning 832 runs. New York has hit 266 HRs over the course of the season as well as 803 RBIs. They have been rung up on 1,437 occasions (3rd in the league) and have recorded 1,349 base hits. The New York Yankees have accounted for an on-base percentage of .332 in addition to a team batting average of .251 over the course of the season.

The Yankees have a team WHIP of 1.253 and are the owners of a FIP of 3.99 as a squad for the year. They come in at 4th in the league as a staff in total hits given up with 1,224. The New York pitching staff have conceded 678 runs so far this season and come in with a team ERA of 3.94 (618 earned runs relinquished). Their K/BB ratio comes in at 9.00 (1,409 strikeouts vs 546 bases on balls). They have surrendered 170 home runs and they relinquish 4.32 runs per 9 innings (15th in the league).

Sitting with 162 save situations, the Yankees have tallied 97 holds in addition to 21 blown saves. New York has had bullpen pitchers step onto the hill in 63 save opportunities and they have come away with 42 saves. Their relievers have stepped onto the mound 161 times in high leverage situations and on 166 occasions with runners on base. New York relief pitchers have an inherited score percentage of 27.8% of 252 inherited base runners. They are ranked 7th in MLB with a save percentage of 66.7%, and they have dispatched 523 bullpen pitchers to the mound this season.

The New York Yankees have turned 105 double plays and have a fielding percentage of .984 (25th in baseball). The Yankees have recorded 1,368 assists, 92 errors and have earned a total of 4,238 putouts this year. Out of their 12,714 innings on the diamond, the Yankees hold a defensive efficiency of 70.6% (9th in MLB).

In his MLB career, Gil has given up 173 base hits while he has earned 253 K's in 237 innings pitched. Gil (20-9 career record) has a 3.49 ERA and has surrendered 6.6 hits per nine innings. He has allowed 92 ER's while earning a WHIP of 1.274 and a FIP of 3.4. His K/BB ratio is 1.96 and he has gone up against 1,010 opposing hitters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Baltimore (+106)

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