Baltimore Orioles vs San Diego Padres Prediction, 9/2/2025 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs San Diego Padres

Date: Tuesday, September 2, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Baltimore (+126) San Diego (-152)

Petco Park is the location where the San Diego Padres (76-61) will compete against the Baltimore Orioles (61-75) on Tuesday. The odds on this game have Baltimore at +126 and San Diego is sitting at -152. The total is set at 8. The pitchers who are expected to start are Tyler Wells and Yu Darvish.

Baltimore owns a slugging percentage of .405 and have been called out on strikes 1,184 times, while being walked on 379 occasions. They have accounted for 561 RBI's in addition to 1,103 base knocks for the year, and their team batting average is at .241. The Orioles have hit 223 two-baggers as a squad and have hit 164 balls out of the stadium. They have 593 runs while having a team on-base percentage of .306. As a squad, the Baltimore Orioles are scoring 4.4 runs per game, which has them sitting at 18th in the league.

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The Orioles are sitting with a team ERA of 4.69 this year (25th in MLB), and their staff has struck out 1,119 hitters. Orioles pitchers have given up 186 long balls and also 670 total runs (25th in MLB). Their pitching staff has walked 432 opposing batters and their FIP is 4.45 as a squad for the season. Baltimore has relinquished 1,217 base knocks (9.1 per 9 innings) as well as 626 earned runs. Their K/BB ratio is 2.59 and the pitching staff has a team WHIP of 1.37.

The Orioles have dispatched 452 relief pitchers to the mound on the season. The relievers have inherited 178 runners so far this year with 25.8% of them crossed home plate. They have earned 31 saves over the course of the season and have blown 18 of their 49 save opportunities. The Orioles bullpen have earned a save percentage of 63.3% and have come into the game in 140 save situations. The bullpen have earned 87 holds so far this year (6th in the league). Orioles bullpen pitchers have entered the contest with opponents on base 131 times in addition to having 137 appearances in high leverage situations.

The Atlanta Braves have earned a total of 3,603 putouts thus far, in addition to 1,190 assists and 72 errors. Their fielding rate is holding steady at .985 which is 19th in baseball, and they have turned 95 double plays. The Orioles have converted 68.4% of balls hit into play into outs out of their 10,809 innings on the field, which has them sitting at 28th in baseball.

Wells (16-18 record in his career) is the owner of a FIP of 4.01 while he has faced 1,184 batters in the major leagues. He has surrendered 231 base hits (7.1 hits per nine innings) and has 77 free passes. His ERA is 4.07 (133 ER's allowed) and his WHIP is 1.047. Wells has taken the mound for 294 innings and is sitting with 271 K's in his pro baseball career.

The San Diego Padres have earned an on-base percentage of .323 and a team batting average of .252 on the campaign. They have been rung up on 953 occasions (28th in MLB) and have earned 1,146 base knocks. San Diego has hit 119 home runs for the year and 545 runs batted in. The Padres have a team slugging percentage of .387 and they average 4.26 runs per outing (21st in MLB). They have recorded 221 doubles, while walking 440 times and putting up 580 runs.

The San Diego pitching staff have given up 520 runs on the campaign while holding a team ERA of 3.61 (482 earned runs relinquished). They have given up 141 homers and they surrender 3.90 runs per 9 innings (2nd in the league). The Padres hold a team WHIP of 1.199 in addition to having a FIP of 3.96 as a unit over the course of the season. Their strikeout to walk ratio sits at 8.70 (1,161 strikeouts against 445 walks). They come in at 1st in the league as a pitching staff in total hits relinquished with 995.

With 153 save situations, the Padres have earned 90 holds in addition to 15 blown saves. San Diego has had relief pitchers enter the contest in 58 save chances and they have earned 43 saves. Their bullpen pitchers have taken the field 183 times in high leverage situations in addition to 157 occasions with runners on. San Diego bullpen pitchers have an inherited score rate of 28.3% out of 223 inherited runners. They are ranked 1st in baseball with a save percentage of 74.1%, and they have dispatched 478 relievers onto the diamond for the year.

The San Diego Padres have gotten 100 double plays and own a fielding percentage of .987 (12th in the majors). The Padres have 1,028 assists, 62 errors and have a total of 3,603 putouts so far this year. In their 10,809 innings on the field, the Padres are sitting with a defensive efficiency of 72.0% (2nd in pro baseball).

Thus far in his career, Darvish has allowed 1,432 base knocks while tallying 2,049 K's in 1,753 innings. Darvish (113-92 mark in his career) has a 3.63 earned run average while allowing 7.4 hits per nine innings. He has conceded a total of 708 ER's while holding a WHIP of 1.136 and having a FIP of 3.6. He has a strikeout to walk ratio of 3.67 and he has faced 7,203 hitters during his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-152)

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