Boston Red Sox vs Cleveland Guardians Prediction, 4/27/2025 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs Cleveland Guardians
Date: Sunday, April 27, 2025
Location: Progressive Field in Cleveland, OH
TV: CLEGuardians.TV
Odds/Point Spread: Boston (+125) Cleveland (-150)
The Cleveland Guardians (14-10) will play the Boston Red Sox (14-13) at Progressive Field on Sunday. The moneyline on this game has Boston at +125 while Cleveland is coming in at -150. The over/under comes in at 8.5. The pitchers taking the mound will be Brayan Bello and Gavin Williams.


Boston has a slugging percentage of .397 and have been rung up 257 times, while being walked on 103 occasions. They have recorded 119 RBI's and 225 base knocks so far this season, and their batting average is sitting at .244. The Red Sox have hit 52 two-baggers as a unit and have smacked 28 baseballs out of the stadium. They have accounted for 124 runs scored while holding a team on-base percentage of .324. As a squad, the Boston Red Sox are notching 4.6 runs per contest, which has them at 9th in baseball.
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Their strikeout to walk ratio sits at 2.65 and the pitching staff has a collective WHIP of 1.33. Red Sox pitchers have given up 23 home runs and 128 runs in total (28th in MLB). Boston has allowed 232 base knocks (8.7 per 9 innings) and 109 earned runs. The Red Sox are sitting with a team ERA of 4.06 this season (17th in MLB), and their staff has rung up 233 hitters. Their pitching staff has walked 88 players from the other team and their FIP comes in at 3.58 as a squad on the season.
The Red Sox have dispatched 83 relief pitchers to the mound on the campaign. The relievers have inherited 28 base runners on the campaign with 53.6% of those runners crossed home plate. They have tallied 8 saves this season and have not converted 5 of their 13 save chances. The Red Sox bullpen have recorded a save rate of 61.5% and have entered the game in 23 save situations. The relievers have racked up 9 holds this season (25th in MLB). Red Sox bullpen pitchers have stepped onto the hill with runners on base 21 times and also have had 27 appearances in high leverage situations.
The Red Sox have transformed 66.6% of baseballs in play into outs out of 2,172 innings, which ranks them 28th in the majors. The Baltimore Orioles have earned 724 putouts on the campaign, in addition to 252 assists and 27 errors. Their fielding rate is holding at .973 which ranks 30th in the majors, and they have turned 27 double plays.
Bello has taken the hill for 381 innings and has totaled 343 K's in his MLB career. His ERA is 4.39 (186 earned runs allowed) and he has a career WHIP of 1.417. He has allowed 401 base knocks (9.5 hits per nine innings) and has 139 free passes. Bello (29-27 career record) has a FIP of 4.33 while he has faced 1,660 opposing hitters in the major leagues.
The Guardians have a team slugging % of .386 and they score 4.00 runs per game (20th in baseball). They have recorded 30 doubles, while walking 78 times as well as scoring 96 runs. Cleveland has hit 28 long balls for the season to go along with 90 runs batted in. They have struck out on 188 occasions (25th in the league) and have earned a total of 183 base knocks. The Cleveland Guardians have tallied a team on-base percentage of .306 in addition to a batting average of .235 for the season.
The Guardians have a WHIP of 1.376 and have a FIP of 4.15 as a pitching staff this year. They rank 16th in the league as a staff in total hits surrendered with 199. The Cleveland pitching staff have surrendered 101 runs over the course of the season while holding a team ERA of 3.94 (92 earned runs allowed). They currently have a strikeout to walk ratio of 9.10 (212 strikeouts vs 90 bases on balls). They have conceded 29 dingers and they relinquish 4.33 runs per 9 innings (14th in the league).
Cleveland has called on relief pitchers to step onto the hill in 11 save chances and they have walked away with 8 saves. They are currently ranked 7th in the league with a save rate of 72.7%, and they have dispatched 84 relievers onto the field on the campaign. Their relievers have stepped onto the mound 21 times in high leverage situations in addition to 22 occasions with runners on base. Cleveland bullpen pitchers hold an inherited score percentage of 13.3% out of their 30 inherited base runners. Sitting with 37 save situations, the Guardians have amassed 26 holds and also 3 blown saves.
In 1,890 innings on the diamond, the Guardians have a defensive efficiency of 68.1% (25th in pro baseball). The Cleveland Guardians have gotten 24 double plays and hold a fielding percentage of .983 (20th in pro baseball). The Guardians have racked up 184 assists, 14 errors and are sitting with 630 putouts for the season.
During his career, Williams has conceded 161 hits while earning 186 K's in 184 frames. Williams (8-16 career record) is the owner of a 4.06 earned run average and has surrendered 7.9 hits per nine innings. He has given up a total of 83 ER's while earning a WHIP of 1.315 and having a FIP of 4.0. His strikeout to walk ratio is 2.30 and he has gone up against 786 opposing batters in his pro baseball career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Boston (+125)
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Additional Resources:
Cleveland Guardians - Twitter
Boston Red Sox - Twitter