Boston Red Sox vs Tampa Bay Rays Prediction, 9/20/2025 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs Tampa Bay Rays

Date: Saturday, September 20, 2025

Location: George M. Steinbrenner Field in Tampa, FL

TV: FanDuel Sports Network Sun

Odds/Point Spread: Boston (-145) Tampa Bay (+125)

The Tampa Bay Rays (74-78) host the Boston Red Sox (83-69) at George M. Steinbrenner Field on Saturday. The moneyline on this game has Boston at -145 and Tampa Bay is coming in at +125. The total is 9. The pitchers who are expected to start are Kyle Harrison and Adrian Houser.

The Red Sox have tallied 303 two-baggers as a team and have smacked 178 baseballs out of the stadium. Boston is slugging .423 and have been called out on strikes 1,330 times, while drawing a walk on 489 occasions. As a team, the Boston Red Sox are putting up 4.9 runs per game, which is 7th in the league. They have earned 707 runs batted in in addition to 1,326 base knocks so far this season, and their batting average sits at .254. They have accounted for 742 runs scored and have an OBP of .324.

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Their K/BB ratio is 2.57 and their pitching staff has a collective WHIP of 1.29. Red Sox pitchers have conceded 155 long balls and 638 runs in total (11th in the league). Boston has conceded 1,262 base knocks (8.4 per 9 innings) in addition to 563 earned runs. The Red Sox have compiled a team ERA of 3.72 for the season (4th in MLB), and they have struck out 1,272 hitters. Their pitching staff has walked 495 opposing batters and their FIP comes in at 4.01 as a team on the season.

The Red Sox relief pitchers have compiled a save rate of 60.9% and have stepped onto the mound in 151 save situations. The bullpen pitchers have inherited 207 base runners on the season and 32.4% of those runners ended up crossing the plate. Red Sox pitchers have come into the game with runners on base 151 times in addition to having 181 appearances in high leverage situations. The Red Sox have dispatched 504 relief pitchers to the mound on the year. The relief pitchers have a total of 80 holds this year (17th in MLB). They have compiled 42 saves so far this season and have missed out on 27 of 69 save chances.

The Red Sox have turned 69.0% of balls hit into play into outs out of their 12,243 innings on the diamond, which has them ranked 23rd in professional baseball. The Baltimore Orioles have accumulated 4,081 putouts so far this season, as well as 1,372 assists and 108 errors. Their fielding percentage is currently at .981 which is 30th in baseball, and they have turned 122 double plays.

Harrison has taken the mound for 185 frames and has 180 punch outs during his pro baseball career. Harrison (9-9 career win-loss record) sits with a FIP of 4.36 and he has faced 792 hitters in the major leagues. His earned run average is 4.42 (91 ER's allowed) and he has a WHIP of 1.296. He has given up 178 base knocks (8.7 hits per nine innings) and has had 62 free passes.

The Rays have a slugging percentage of .403 and they are scoring 4.44 runs per outing (14th in the league). They have 229 doubles, while getting a free base 437 times as well as racking up 675 runs. Tampa Bay has tallied 172 home runs for the season and 643 runs batted in. They have been called out on strikes on 1,305 occasions (11th in the league) and have a total of 1,289 base knocks. The Tampa Bay Rays hold a team OBP of .313 in addition to a batting average of .251 so far this season.

The Tampa Bay pitching staff have given up 627 runs so far this season while having an ERA of 3.86 (577 earned runs relinquished). They have conceded 193 dingers and they give up 4.19 runs per 9 innings (10th in MLB). The Rays have a team WHIP of 1.206 and are the owners of a FIP of 4.15 as a staff this year. Their K/BB ratio comes in at 8.90 (1,329 strikeouts vs 436 walks). They sit at 6th in baseball as a staff in total hits conceded with 1,188.

With 147 save situations, the Rays have compiled 83 holds in addition to 27 blown saves. Tampa Bay has had bullpen pitchers take the mound in 62 save chances and they have earned 35 saves. Their bullpen pitchers have taken the field 151 times in high leverage situations and on 107 occasions with runners on base. Tampa Bay relief pitchers hold an inherited score percentage of 31.2% out of their 157 inherited base runners. They rank 26th in baseball holding a save rate of 56.5%, and they have dispatched 487 bullpen pitchers to the mound this year.

In their 12,117 innings played, the Rays have accumulated a defensive efficiency of 70.8% (6th in professional baseball). The Tampa Bay Rays have turned 138 double plays and hold a fielding percentage of .987 (11th in the majors). The Rays have accrued 1,331 assists, 72 errors and are sitting with 4,039 putouts so far this year.

During his MLB career, Houser has surrendered 704 base knocks and he has 569 punch outs in 721 innings pitched. He has given up 324 ER's while holding a WHIP of 1.360 and a FIP of 4.0. He has a strikeout to walk ratio of 2.05 and he has faced 3,085 batters so far in his pro baseball career. Houser (40-43 career win-loss record) has earned a 4.04 earned run average while giving up 8.8 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Boston (-145)

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