Chicago Cubs vs Atlanta Braves Prediction, 9/10/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs Atlanta Braves

Date: Wednesday, September 10, 2025

Location: Truist Park in Cumberland, GA

TV: FanDuel Sports Network South

Odds/Point Spread: Chicago (-132) Atlanta (+110)

Truist Park is the location where the Atlanta Braves (65-79) will try to beat the Chicago Cubs (81-63) on Wednesday. The odds on this game have Chicago at -132 and Atlanta is sitting at +110. The over/under is set at 8. The expected starting pitchers are Jameson Taillon and Chris Sale.

The Cubs have accrued 237 two-baggers as a team and have knocked 195 baseballs out of the park. Chicago has a slugging % of .426 and have been called out on strikes 1,115 times, while drawing a walk on 491 occasions. As a team, the Chicago Cubs are notching 4.9 runs per game, which ranks them 7th in MLB. They have accrued 688 runs batted in in addition to 1,212 base knocks this year, while their batting average is at .248. They have racked up 704 runs while holding a team OBP of .319.

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The Cubs have compiled a team ERA of 3.89 on the campaign (10th in MLB), and their staff has rung up 1,106 hitters. Cubs pitchers have conceded 179 home runs and 590 total runs (7th in baseball). Their pitching staff has walked 368 opposing batters and their FIP sits at 4.21 as a squad this year. Chicago has conceded 1,161 base knocks (8.2 per 9 innings) as well as 552 earned runs. Their strikeout to walk ratio sits at 3.01 and their pitching staff has recorded a WHIP of 1.20.

The Cubs have dispatched 466 relief pitchers to the hill over the course of the season. The relief pitchers have inherited 128 base runners so far this season and 32.8% of those runners earned a run for their team. They have earned 37 saves so far this year and have blown 17 of 54 chances to get a save. The Cubs bullpen have accumulated a save rate of 68.5% and stepped onto the hill in 152 save situations. The relievers have recorded 95 holds for the year (3rd in MLB). Cubs relief pitchers have entered the contest with opponents on base 92 times and also have had 141 appearances in high leverage situations.

The Cubs have transformed 71.6% of balls in play into outs out of 11,493 innings on the diamond, which has them ranked 3rd in MLB. The Boston Red Sox have 3,831 putouts over the course of the season, as well as 1,207 assists and 56 errors. Their fielding percentage is holding steady at .989 which has them sitting 4th in pro baseball, and they have turned 112 double plays.

Taillon has taken the ball for 1,213 innings and is sitting with 1,056 strikeouts in his MLB career. Taillon (80-59 career win-loss mark) is the owner of a FIP of 3.86 and he has gone up against 5,039 hitters in the majors. His ERA is 3.92 (528 ER's allowed) and his WHIP is 1.198. He has allowed 1,166 hits (8.6 hits per 9 innings) and has had 288 walks.

The Braves have a team SLG% of .393 and they average 4.38 runs per game (15th in MLB). They have recorded 216 doubles, while getting a free base 506 times and scoring 630 runs. Atlanta has compiled 162 HRs this year and 609 RBIs. They have struck out on 1,241 occasions (11th in the league) and have 1,191 hits. The Atlanta Braves hold an on-base percentage of .318 and a batting average of .243 on the year.

The Braves hold a team WHIP of 1.310 and are the owners of a FIP of 4.29 as a squad for the season. They have a ranking of 17th in the league as a pitching staff in total hits conceded with 1,192. The Atlanta pitching staff have given up 663 runs for the year and come in with a team ERA of 4.45 (630 earned runs given up). They have earned a K/BB ratio of 8.70 (1,235 strikeouts against 478 bases on balls). They have surrendered 178 long balls and they give up 4.68 runs per 9 innings (20th in MLB).

With 109 save situations, the Braves have amassed 60 holds in addition to 20 blown saves. Atlanta has had relief pitchers enter the game in 49 save chances and they have walked away with 29 saves. Their relief pitchers have come in 155 times in high leverage situations and on 148 occasions with runners on. Atlanta relievers hold an inherited score percentage of 38.6% out of 197 inherited runners. They rank 24th in the league holding a save percentage of 59.2%, and they have dispatched 463 bullpen pitchers onto the diamond on the campaign.

Out of their 11,475 innings on the diamond, the Braves hold a defensive efficiency of 70.1% (13th in professional baseball). The Atlanta Braves have turned 96 double plays and have notched a fielding percentage of .990 (2nd in MLB). The Braves have recorded 1,225 assists, 49 errors and have accumulated 3,825 putouts this season.

So far in his pro baseball career, Sale has given up 1,675 hits while he has totaled 2,546 strikeouts in 2,060 frames. Sale (143-87 win-loss record in his career) is the owner of a 3.01 ERA while allowing 7.3 hits per nine innings. He has allowed 688 ER's while holding a WHIP of 1.047 and a FIP of 3.0. His strikeout to walk ratio is 5.28 and he has gone up against 8,294 hitters thus far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Atlanta (+110) and under 8 runs

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