Chicago Cubs vs Houston Astros Prediction, 6/27/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs Houston Astros

Date: Friday, June 27, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Chicago (+120) Houston (-144)

The Chicago Cubs (47-33) are en route to Daikin Park on Friday where they will play the Houston Astros (47-33). The line on this contest has the Cubs at +120 while the Astros are sitting at -144. The total is 8.5. The pitchers expected to start will be Cade Horton and Brandon Walter.

The Cubs have earned 141 two-baggers as a team and have smacked 118 balls out of the stadium. Chicago has a slugging percentage of .445 and have struck out 629 times, while being walked on 277 occasions. As a team, the Chicago Cubs are knocking in 5.4 runs per contest, which ranks them 2nd in the league. They have accumulated 426 RBI's as well as 708 base knocks over the course of the season, while their batting average is sitting at .255. They have racked up 434 runs scored while holding a team OBP of .325.

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Their K/BB ratio is 2.74 and their pitching staff has earned a collective WHIP of 1.26. Cubs pitchers have surrendered 95 long balls and also 337 runs (15th in baseball). Chicago has surrendered 677 base hits (8.5 per 9 innings) and 310 earned runs. The Cubs have an ERA of 3.90 on the year (16th in the league), and their staff has rung up 608 hitters. Their pitching staff has walked 222 opposing hitters and their FIP sits at 4.14 as a squad for the year.

The Cubs have sent 268 relievers to the mound so far this season. The relief pitchers have inherited 81 base runners so far this season with 32.1% of those players crossed home plate. They have compiled 18 saves this season and have missed out on 9 of their 27 save chances. The Cubs relief pitchers have a save percentage of 66.7% and have come into the game in 79 save situations. The relief pitchers have racked up 49 holds for the year (12th in MLB). Cubs pitchers have stepped onto the hill with runners on base 60 times as well as having 90 appearances in high leverage situations.

The Boston Red Sox have accounted for 2,147 putouts this year, as well as 692 assists and 35 errors. Their fielding rate is holding at .988 which is 7th in the majors, and have a total of 72 double plays. The Cubs have turned 70.4% of baseballs in play into outs out of their 6,441 innings on the diamond, which has them ranked 13th in professional baseball.

Horton (3-1 career win-loss mark) is the owner of a FIP of 3.68 and he has gone up against 176 hitters during his time in the major leagues. He has surrendered 43 base hits (9.4 hits per nine innings) with 10 walks. His ERA is 3.73 (17 ER's allowed) and his WHIP is 1.293. Horton has pitched in 41 innings and has tallied 31 K's in his MLB career.

Houston has compiled 86 HRs over the course of the season as well as 320 runs batted in. They have recorded 115 doubles, while walking 235 times and putting up 336 runs. The Houston Astros have compiled an OBP of .322 as well as a batting average of .256 this year. The Astros have a team slugging % of .400 and they average 4.20 runs per outing (20th in MLB). They have been rung up on 624 occasions (24th in baseball) and are sitting with 684 base knocks.

The Astros hold a team WHIP of 1.150 and have a FIP of 3.55 as a pitching staff on the year. They rank 1st in the league as a staff in total hits relinquished with 573. The Houston pitching staff have allowed 287 runs for the year while holding a team ERA of 3.44 (270 earned runs surrendered). Their K/BB ratio is 10.00 (784 strikeouts vs 240 bases on balls). They have surrendered 84 dingers and they allow 3.65 runs per 9 innings (2nd in MLB).

Houston bullpen pitchers hold an inherited score percentage of 28.2% out of 85 inherited runners. Their relievers have stepped onto the mound 81 times in high leverage situations and also on 58 occasions with base runners. With 83 save situations, the Astros have earned 51 holds in addition to 8 blown saves. They are currently ranked 2nd in the league holding a save percentage of 75.0%, and they have dispatched 247 relievers to the hill this season. Houston has called on bullpen pitchers to step onto the hill in 32 save opportunities and they have tallied 24 saves.

The Houston Astros have turned 50 double plays and have a fielding percentage of .986 (17th in baseball). The Astros have accrued 605 assists, 38 errors and have notched a total of 2,123 putouts on the season. In 6,369 innings on the diamond, the Astros have accumulated a efficiency on defense of 71.1% (7th in the majors).

So far in his MLB career, Walter has allowed 56 base hits while accumulating 41 K's in 46 frames. He has surrendered a total of 26 earned runs while holding a WHIP of 1.407 and being the owner of a FIP of 5.0. He has a strikeout to walk ratio of 4.56 and he has gone up against 205 hitters so far in his MLB career. Walter (0-1 career win-loss record) holds a 5.06 earned run average and has given up 10.9 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (-144)

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