Chicago Cubs vs Pittsburgh Pirates Prediction, 4/29/2025 MLB Picks, Best Bets & Odds
Game: Chicago Cubs vs Pittsburgh Pirates
Date: Tuesday, April 29, 2025
Location: PNC Park in Pittsburgh, PA
TV: SportsNet Pittsburgh
Odds/Point Spread: Chicago (-150) Pittsburgh (+125)
PNC Park is the location where the Pittsburgh Pirates (11-18) will play the Chicago Cubs (17-12) on Tuesday. The moneyline on this contest has Chicago at -150 and Pittsburgh is at +125. The total comes in at 8. The pitchers expected to start will be Shota Imanaga and Andrew Heaney.


The Cubs have earned 57 doubles as a squad and have hit 38 baseballs out of the stadium. Chicago is slugging .444 and have been rung up 243 times, while drawing a walk on 118 occasions. As a squad, the Chicago Cubs are notching 5.9 runs per game, which has them at 1st in baseball. They have 169 RBI's and 265 hits for the year, and their team batting average comes in at .260. They have 172 runs while holding a team on-base percentage of .340.
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The Cubs are sitting with a team earned run average of 4.24 for the season (20th in the league), and they have rung up 230 batters. Cubs pitchers have surrendered 33 home runs and also 133 total runs (23rd in baseball). They have walked 104 players from the other team and their FIP is 4.24 as a team for the season. Chicago has conceded 250 hits (8.6 per 9 innings) and 123 earned runs. They have accumulated a K/BB ratio of 2.21 and their pitching staff has recorded a WHIP of 1.36.
The Cubs relief pitchers have accumulated a save percentage of 53.8% and have entered the game in 33 save situations. The bullpen pitchers have inherited 34 runners on the season and 38.2% of them ended up crossing the plate. Cubs relief pitchers have entered the contest with runners on base 24 times as well as having 33 appearances in high leverage situations. The Cubs have sent 102 relief pitchers to the hill over the course of the season. The bullpen have 19 holds on the campaign (7th in MLB). They have accumulated 7 saves for the year and have missed out on 6 out of their 13 chances to get a save.
The Boston Red Sox have accounted for 783 putouts for the season, as well as 231 assists and 16 errors. Their fielding percentage is holding steady at .984 which is 20th in MLB, and have accumulated 18 double plays. The Cubs have turned 69.8% of balls in play into outs in their 2,349 innings, which has them ranked 16th in the majors.
Imanaga (17-4 career mark) holds a FIP of 2.91 while he has gone up against 832 hitters in the majors. He has surrendered 174 hits (7.6 hits per 9 innings) and has 40 free passes. His earned run average is 2.96 (68 ER's allowed) and he has a career WHIP of 1.033. Imanaga has taken the hill for 207 innings and has accumulated 201 punch outs during his career.
Pittsburgh has hit 23 HRs this year and 100 runs batted in. They have recorded 34 two-baggers, while getting a free base 102 times as well as scoring 102 runs. The Pittsburgh Pirates have accounted for an OBP of .304 and a team batting average of .224 this season. The Pirates hold a slugging % of .341 and they score 3.52 runs per game (25th in MLB). They have been called out on strikes on 258 occasions (5th in MLB) and have notched a total of 217 base knocks.
The Pirates hold a team WHIP of 1.215 and have a FIP of 3.58 as a staff over the course of the season. They come in at 16th in baseball as a staff in total hits conceded with 227. The Pittsburgh pitching staff have conceded 127 runs so far this year while holding an ERA of 3.98 (115 earned runs relinquished). Their strikeout to walk ratio comes in at 7.80 (227 strikeouts vs 89 bases on balls). They have given up 22 long balls and they yield 4.39 runs per 9 innings (15th in baseball).
Sitting with 30 save situations, the Pirates have 19 holds in addition to 5 blown saves. Pittsburgh has had relief pitchers step onto the hill in 11 save chances and they have come away with 6 saves. Their relief pitchers have stepped onto the hill 34 times in high leverage situations in addition to 27 occasions with base runners. Pittsburgh relief pitchers hold an inherited score rate of 31.0% out of 42 inherited base runners. They are ranked 23rd in the league with a save percentage of 54.5%, and they have sent 95 relief pitchers to the mound this year.
In 2,343 innings played, the Pirates have a efficiency on defense of 70.2% (14th in baseball). The Pittsburgh Pirates have gotten 24 double plays and own a fielding percentage of .978 (27th in pro baseball). The Pirates have accrued 262 assists, 24 errors and have earned 781 putouts on the season.
Thus far in his career, Heaney has conceded 1,002 base hits while tallying 1,101 punch outs in 1,045 frames. He has given up a total of 508 earned runs while earning a WHIP of 1.250 and a FIP of 4.3. He has a K/BB ratio of 3.61 and he has faced 4,447 opposing hitters during his pro baseball career. Heaney (53-63 win-loss record in his career) holds a 4.37 ERA while allowing 8.6 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Pittsburgh (+125)
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Additional Resources:
Pittsburgh Pirates - Twitter
Chicago Cubs - Twitter