Chicago Cubs vs Pittsburgh Pirates Prediction, 4/30/2025 MLB Picks, Best Bets & Odds

Game: Chicago Cubs vs Pittsburgh Pirates

Date: Wednesday, April 30, 2025

Location: PNC Park in Pittsburgh, PA

TV: SportsNet Pittsburgh

Odds/Point Spread: Chicago (-132) Pittsburgh (+110)

The Chicago Cubs (17-12) are en route to PNC Park on Wednesday where they will meet the Pittsburgh Pirates (11-18). The moneyline on this game has Chicago at -132 while Pittsburgh is coming in at +110. The total is 8.5. The pitchers taking the mound will be Matthew Boyd and Carmen Mlodzinski.

As a team, the Chicago Cubs are earning 5.9 runs per contest, which is 1st in baseball. They are sitting with 172 runs scored while holding a team on-base percentage of .340. The Cubs have accounted for 57 two-baggers as a team and have hit 38 baseballs out of the park. They have 169 RBI's in addition to 265 hits so far this season, while their batting average is at .260. Chicago has a slugging rate of .444 and have struck out 243 times, while taking a walk on 118 occasions.

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Their strikeout to walk ratio is 2.21 and their pitching staff has a collective WHIP of 1.36. Cubs pitchers have given up 33 home runs in addition to 133 runs in total (20th in baseball). Chicago has surrendered 250 base hits (8.6 per 9 innings) and 123 earned runs. The Cubs are sitting with a team ERA of 4.24 so far this year (20th in the league), and their staff has rung up 230 batters. They have walked 104 opposing hitters and their FIP comes in at 4.26 as a team so far this year.

Cubs bullpen pitchers have come into the game with runners on 24 times as well as having 33 appearances in high leverage situations. The relievers have accumulated 19 holds on the season (8th in the league). The Cubs bullpen have recorded a save rate of 53.8% and stepped onto the hill in 33 save situations. They have compiled 7 saves over the course of the season and have missed out on 6 of 13 save opportunities. The relief pitchers have inherited 34 runners so far this year and 38.2% of them earned a run for their team. The Cubs have dispatched 102 relief pitchers to the mound on the year.

The Boston Red Sox are sitting with 783 putouts so far this season, as well as 231 assists and 16 errors. Their fielding percentage is at .984 which is 20th in professional baseball, and they have turned 18 double plays. The Cubs have turned 69.8% of balls in play into outs in their 2,349 innings, which ranks them 17th in professional baseball.

Boyd (48-71 career mark) sits with a FIP of 4.71 while he has faced 4,019 opposing batters in the major leagues. He has conceded 928 base hits (8.9 hits per 9 innings) and has had 304 free passes. His earned run average is 4.78 (497 ER's allowed) and he has a career WHIP of 1.316. Boyd has thrown 936 innings and has 915 strikeouts so far in his MLB career.

The Pittsburgh Pirates have an OBP of .304 in addition to a team batting average of .224 for the season. They have struck out on 258 occasions (6th in MLB) and have 217 base hits. Pittsburgh has 23 home runs for the season and 100 RBIs. The Pirates hold a team slugging % of .341 and they average 3.52 runs per outing (25th in the league). They have recorded 34 doubles, while getting a free base 102 times and putting up 102 runs.

The Pirates have a WHIP of 1.215 with a FIP of 3.60 as a unit on the year. They are sitting at 15th in the league as a staff in total hits conceded with 227. The Pittsburgh pitching staff have relinquished 127 runs over the course of the season while having an ERA of 3.98 (115 earned runs given up). They have earned a strikeout to walk ratio of 7.80 (227 strikeouts against 89 walks). They have given up 22 homers and they concede 4.39 runs per 9 innings (15th in the league).

With 30 save situations, the Pirates have 19 holds in addition to 5 blown saves. Pittsburgh has called on bullpen pitchers to step onto the mound in 11 save chances and they have tallied 6 saves. Their bullpen pitchers have stepped onto the hill 34 times in high leverage situations and on 27 occasions with runners on. Pittsburgh relievers hold an inherited score rate of 31.0% out of their 42 inherited runners. They rank 24th in the league with a save rate of 54.5%, and they have sent 95 relief pitchers onto the field on the campaign.

Out of their 2,343 innings on the diamond, the Pirates have a defensive efficiency of 70.2% (14th in the majors). The Pittsburgh Pirates have gotten 24 double plays and own a fielding percentage of .978 (28th in professional baseball). The Pirates have recorded 262 assists, 24 errors and have a total of 781 putouts for the season.

So far in his pro baseball career, Mlodzinski has surrendered 100 base hits while he has accumulated 98 punch outs in 108 innings pitched. Mlodzinski (9-11 record in his career) is the owner of a 3.74 ERA and has conceded 8.3 hits per nine innings. He has allowed 45 ER's while earning a WHIP of 1.349 and being the owner of a FIP of 3.7. He has a strikeout to walk ratio of 2.13 and he has gone up against 465 hitters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Pittsburgh (+110)

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