Chicago Cubs vs Washington Nationals Prediction, 6/5/2025 MLB Picks, Best Bets & Odds
Game: Chicago Cubs vs Washington Nationals
Date: Thursday, June 5, 2025
Location: Nationals Park in Washington, D.C.
TV: MASN
Odds/Point Spread: Chicago (-130) Washington (+110)
The Washington Nationals (28-32) will try to defeat the Chicago Cubs (38-22) at Nationals Park on Thursday. The odds on this game have Chicago at -130 and Washington is coming in at +110. The over/under has been set at 8. The pitchers expected to start will be Colin Rea and Jake Irvin.


Chicago has a slugging percentage of .448 and have been called out on strikes 473 times, while taking a walk on 227 occasions. They have 341 RBI's as well as 545 base knocks this year, while their team batting average comes in at .262. The Cubs have recorded 115 doubles as a team and have smacked 81 baseballs out of the park. They have tallied 349 runs scored while holding a team on-base percentage of .335. As a unit, the Chicago Cubs are knocking in 5.8 runs per game, which has them sitting at 1st in the league.
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The Cubs have a team ERA of 3.83 on the campaign (13th in baseball), and their staff has struck out 477 batters. Cubs pitchers have surrendered 67 long balls and 247 runs (12th in the league). They have walked 177 players from the other team and their FIP sits at 4.01 as a squad for the year. Chicago has given up 495 hits (8.3 per 9 innings) and 229 earned runs. They have accumulated a K/BB ratio of 2.69 and the pitching staff has a collective WHIP of 1.25.
Cubs relief pitchers have gone to the mound with opponents on base 44 times in addition to having 65 appearances in high leverage situations. The bullpen have a total of 41 holds for the year (7th in MLB). The Cubs relievers have accumulated a save percentage of 65.2% and have stepped onto the mound in 65 save situations. They have recorded 15 saves this year and have blown 8 of their 23 chances to get a save. The bullpen pitchers have inherited 62 runners on the season and 32.3% of them crossed home plate. The Cubs have dispatched 206 relievers to the hill so far this year.
The Cubs have turned 70.5% of balls in play into outs out of their 4,848 innings, ranking them 13th in pro baseball. The Boston Red Sox have earned 1,616 putouts at this point in the season, as well as 510 assists and 28 errors. Their fielding percentage sits at .987 which ranks 12th in professional baseball, and they have turned 52 double plays.
Rea (29-22 win-loss mark in his career) has earned a FIP of 4.45 while facing 2,124 hitters in the majors. He has allowed 488 base hits (8.8 hits per nine innings) with 154 walks. His ERA is 4.52 (250 ER's allowed) and he has a WHIP of 1.288. Rea has taken the mound for 498 innings and has accounted for 409 strikeouts in his MLB career.
The Nationals hold a team slugging % of .395 and they score 4.47 runs per contest (12th in the league). They have hit 103 doubles, while getting a free base 175 times and recording 268 runs. Washington is sitting with 60 long balls on the year to go along with 255 runs batted in. They have struck out on 467 occasions (24th in MLB) and have earned 488 hits. The Washington Nationals have compiled an OBP of .312 and a batting average of .244 for the year.
The Nationals have a WHIP of 1.395 in addition to having a FIP of 4.13 as a staff on the year. Their strikeout to walk ratio is 8.10 (477 strikeouts against 208 free passes). They rank 23rd in the league as a pitching staff in total hits surrendered with 527. They have allowed 59 dingers and they yield 5.29 runs per 9 innings (26th in MLB). The Washington pitching staff have surrendered 310 runs over the course of the season while having an ERA of 5.07 (297 earned runs relinquished).
Washington has called on relief pitchers to step onto the hill in 25 save opportunities and they have tallied 17 saves. They rank 9th in baseball with a save percentage of 68.0%, and they have sent 205 relievers to the hill so far this year. Their relievers have taken the field 44 times in high leverage situations in addition to 68 occasions with runners on. Washington relievers have an inherited score rate of 42.1% out of their 121 inherited base runners. With 51 save situations, the Nationals have earned 26 holds in addition to 8 blown saves.
In 4,743 innings on the diamond, the Nationals hold a efficiency on defense of 68.0% (23rd in professional baseball). The Washington Nationals have gotten 43 double plays and hold a fielding percentage of .985 (21st in professional baseball). The Nationals have 508 assists, 32 errors and have notched a total of 1,581 putouts this year.
Irvin (18-22 win-loss mark in his career) is the owner of a 4.39 ERA while surrendering 8.4 hits per nine innings. His K/BB ratio is 2.40 and he has gone up against 1,601 batters during his MLB career. He has conceded a total of 186 earned runs while holding a WHIP of 1.267 and being the owner of a FIP of 4.3. In his MLB career, Irvin has surrendered 357 base hits while tallying 302 punch outs in 381 frames.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Washington (+110)
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Additional Resources:
Washington Nationals - Twitter
Chicago Cubs - Twitter