Chicago White Sox vs Detroit Tigers Prediction, 9/5/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Detroit Tigers

Date: Friday, September 5, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: Chicago (+106) Detroit (-128)

The Chicago White Sox (52-88) are hitting the road to Comerica Park on Friday where they will play the Detroit Tigers (81-60). The moneyline on this contest has the White Sox at +106 and the Tigers are coming in at -128. The over/under has been set at 9. The expected starting pitchers will be Shane Smith and Jack Flaherty.

As a team, the Chicago White Sox are putting up 4.0 runs/g, which is 26th in baseball. They have racked up 558 runs scored while holding a team OBP of .303. The White Sox have accumulated 212 two-baggers as a team and have knocked 143 balls out of the park. They have accrued 539 runs batted in as well as 1,091 base knocks on the year, while their batting average is at .234. Chicago has a slugging percentage of .376 and have been called out on strikes 1,165 times, while drawing a walk on 439 occasions.

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The White Sox have an earned run average of 4.20 over the course of the season (19th in the league), and their staff has struck out 1,081 batters. White Sox pitchers have surrendered 155 long balls in addition to 639 total runs (20th in baseball). Their pitching staff has walked 519 opposing players and their FIP sits at 4.46 as a squad so far this season. Chicago has conceded 1,157 base hits (8.5 per 9 innings) and also 572 earned runs. They have earned a strikeout to walk ratio of 2.08 and their pitching staff has a collective WHIP of 1.37.

The White Sox have dispatched 449 relievers to the mound on the season. The bullpen pitchers have inherited 200 base runners for the year and 32.5% of those players ended up scoring. They have earned 20 saves on the season and have blown 21 of 41 save opportunities. The White Sox relief pitchers have a save percentage of 48.8% and stepped onto the hill in 97 save situations. The relief pitchers have accumulated 56 holds this year (28th in baseball). White Sox relief pitchers have gone to the mound with opponents on base 137 times in addition to having 126 appearances in high leverage situations.

The Chicago Cubs are sitting with 3,676 putouts thus far, as well as 1,121 assists and 91 errors. Their fielding percentage is holding at .981 which is 28th in the majors, and have a total of 112 double plays. The White Sox have transformed 69.6% of balls in play into outs in their 11,028 innings on the field, which has them sitting at 18th in the majors.

Smith has taken the ball for 120 innings and is sitting with 112 strikeouts during his pro baseball career. Smith (4-7 record in his career) has a FIP of 3.76 while he has gone up against 510 hitters during his time in the majors. His earned run average is 3.82 (51 earned runs allowed) and his career WHIP is 1.207. He has given up 95 hits (7.1 hits per 9 innings) and has had 50 walks.

Detroit has tallied 177 home runs so far this year to go along with 653 RBIs. They have 216 two-baggers, while taking a walk 440 times as well as notching 680 runs. The Detroit Tigers have accumulated an on-base percentage of .320 in addition to a team batting average of .251 this season. The Tigers have a slugging percentage of .422 and they are recording 4.82 runs per contest (8th in MLB). They have struck out on 1,242 instances (5th in the league) and have earned 1,191 base hits.

The Tigers have a team WHIP of 1.237 with a FIP of 4.02 as a pitching staff this season. They sit at 11th in baseball as a staff in total hits relinquished with 1,132. The Detroit pitching staff have allowed 595 runs over the course of the season while having an ERA of 3.89 (540 earned runs relinquished). They have earned a K/BB ratio of 8.60 (1,190 strikeouts vs 414 free passes). They have conceded 160 dingers and they surrender 4.28 runs per 9 innings (12th in baseball).

Detroit has had bullpen pitchers take the mound in 54 save opportunities and they have walked away with 36 saves. They are ranked 7th in MLB with a save percentage of 66.7%, and they have sent 433 relievers onto the diamond so far this season. Their relief pitchers have come in 120 times in high leverage situations and also on 152 occasions with runners on. Detroit bullpen pitchers hold an inherited score rate of 27.1% out of 210 inherited runners. With 123 save situations, the Tigers have compiled 65 holds and also 18 blown saves.

In their 11,256 innings on the diamond, the Tigers have earned a efficiency on defense of 70.2% (11th in baseball). The Detroit Tigers have gotten 114 double plays and hold a fielding percentage of .986 (18th in pro baseball). The Tigers have recorded 1,211 assists, 73 errors and have 3,752 putouts this year.

Flaherty (62-54 career record) has a 3.80 ERA while surrendering 7.6 hits per nine innings. His K/BB ratio is 3.23 and he has faced 4,041 opposing batters during his pro baseball career. He has allowed 410 earned runs while earning a WHIP of 1.198 and a FIP of 3.7. During his MLB career, Flaherty has surrendered 820 base knocks while he has earned 1,111 punch outs in 971 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Detroit (-128)

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