Chicago White Sox vs Houston Astros Prediction, 6/11/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Houston Astros

Date: Wednesday, June 11, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Chicago (+125) Houston (-145)

The Chicago White Sox (22-44) are headed to Daikin Park on Wednesday where they will try to defeat the Houston Astros (36-29). The moneyline on this game has the White Sox at +125 and the Astros are opening at -145. The total is 9. The starting pitchers will be Sean Burke and Ryan Gusto.

As a team, the Chicago White Sox are scoring 3.5 runs/g, which is 26th in the league. They are sitting with 233 runs scored while having a team on-base percentage of .296. The White Sox have accumulated 99 two-baggers as a squad and have knocked 52 baseballs out of the park. They have recorded 223 runs batted in as well as 478 hits for the year, and their batting average comes in at .223. Chicago has a slugging rate of .345 and have been called out on strikes 551 times, while drawing a walk on 219 occasions.

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Their strikeout to walk ratio is 2.00 and the pitching staff has recorded a WHIP of 1.38. White Sox pitchers have conceded 72 long balls and also 284 runs (19th in MLB). Chicago has allowed 543 base knocks (8.6 per 9 innings) and 261 earned runs. The White Sox have compiled a team ERA of 4.12 for the year (21st in the league), and the staff has rung up 480 batters. They have walked 240 opposing batters and their FIP comes in at 4.51 as a squad for the season.

The White Sox relief pitchers have a save percentage of 35.3% and stepped onto the hill in 48 save situations. The relief pitchers have inherited 92 base runners on the year and 30.4% of those players earned a run for their team. White Sox relief pitchers have stepped onto the hill with players on base 64 times in addition to having 61 appearances in high leverage situations. The White Sox have dispatched 211 relievers to the hill on the season. The bullpen have 31 holds on the season (25th in baseball). They have tallied 6 saves this season and have blown 11 out of their 17 save opportunities.

The White Sox have turned 69.8% of baseballs in play into outs in their 5,127 innings, which has them sitting 19th in professional baseball. The Chicago Cubs have a total of 1,709 putouts on the campaign, as well as 536 assists and 41 errors. Their fielding percentage is holding at .982 which has them ranked 25th in the majors, and they have turned 52 double plays.

Burke has taken the ball for 86 frames and has accounted for 72 strikeouts during his career. Burke (5-6 win-loss record in his career) has earned a FIP of 3.40 while he has faced 367 batters in the major leagues. His ERA is 3.45 (33 ER's allowed) and his WHIP is 1.302. He has given up 73 hits (7.6 hits per nine innings) and has 39 walks.

The Houston Astros have accounted for a team OBP of .316 in addition to a batting average of .250 for the year. They have been rung up on 496 instances (26th in the league) and have earned a total of 542 hits. Houston has a total of 65 long balls this season and 249 runs batted in. The Astros have a SLG% of .386 and they have an average of 4.02 runs per outing (23rd in the league). They have put up 87 two-baggers, while getting a free base 185 times as well as racking up 261 runs.

The Astros hold a team WHIP of 1.164 with a FIP of 3.48 as a squad so far this year. Their strikeout to walk ratio is 9.80 (623 strikeouts against 202 free passes). They sit at 1st in MLB as a staff in total hits given up with 464. They have allowed 62 dingers and they allow 3.74 runs per 9 innings (6th in baseball). The Houston pitching staff have given up 238 runs on the season while having a team ERA of 3.52 (224 earned runs relinquished).

Houston bullpen pitchers have an inherited score percentage of 29.7% out of their 74 inherited runners. Their bullpen pitchers have taken the field 61 times in high leverage situations and on 50 occasions with base runners. With 68 save situations, the Astros have amassed 42 holds and also 7 blown saves. They are currently ranked 3rd in MLB holding a save percentage of 73.1%, and they have dispatched 202 relief pitchers to the mound so far this season. Houston has had bullpen pitchers step onto the mound in 26 save opportunities and they have come away with 19 saves.

The Houston Astros have turned 38 double plays and have a fielding rate of .988 (9th in the majors). The Astros have recorded 487 assists, 27 errors and have amassed 1,717 putouts this year. In 5,151 innings played, the Astros hold a defensive efficiency of 71.2% (9th in professional baseball).

So far in his career, Gusto has surrendered 50 base knocks while totaling 45 punch outs in 43 innings. He has allowed a total of 23 earned runs while holding a WHIP of 1.647 and being the owner of a FIP of 4.7. He has a strikeout to walk ratio of 2.14 and he has faced 201 opposing batters in his career. Gusto (3-3 career win-loss mark) has earned a 4.80 ERA and has allowed 10.4 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (-145)

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