Chicago White Sox vs Kansas City Royals Prediction, 5/6/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Kansas City Royals

Date: Tuesday, May 6, 2025

Location: Kauffman Stadium in Kansas City, MO

TV: FanDuel Sports Network Kansas City

Odds/Point Spread: Chicago (+125) Kansas City (-145)

The Kansas City Royals (19-16) will take on the Chicago White Sox (10-24) at Kauffman Stadium on Tuesday. The moneyline on this game has Chicago at +125 and Kansas City is coming in at -145. The total comes in at 8.5. The starting pitchers are Sean Burke and Seth Lugo.

Chicago is slugging .328 and have been called out on strikes 287 times, while drawing a walk on 121 occasions. They have recorded 121 RBI's in addition to 237 base knocks on the campaign, and their batting average is sitting at .216. The White Sox have earned 43 doubles as a team and have knocked 26 baseballs out of the stadium. They have notched a total of 124 runs and hold an on-base percentage of .297. As a unit, the Chicago White Sox are scoring 3.7 runs per game, which has them sitting at 24th in the league.

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The White Sox have an earned run average of 4.16 this year (17th in the league), and the staff has rung up 257 hitters. White Sox pitchers have conceded 39 home runs and also 148 total runs (16th in MLB). They have walked 133 opposing batters and their FIP comes in at 4.66 as a unit on the season. Chicago has given up 267 base hits (8.2 per 9 innings) and also 135 earned runs. They have a strikeout to walk ratio of 1.93 and the pitching staff has a collective WHIP of 1.37.

The White Sox have dispatched 110 relief pitchers to the mound so far this year. The bullpen pitchers have inherited 42 runners for the season with 38.1% of those runners crossed home plate. They have accumulated 1 save over the course of the season and have blown 3 of 4 chances to save the game. The White Sox relief pitchers have a save percentage of 25.0% and have entered the game in 15 save situations. The bullpen have a total of 11 holds so far this year (27th in the league). White Sox pitchers have entered the game with opponents on base 29 times in addition to having 26 appearances in high leverage situations.

The White Sox have turned 70.1% of balls in play into outs out of 2,628 innings on the diamond, which ranks them 17th in the majors. The Chicago Cubs have a tally of 876 putouts thus far, in addition to 279 assists and 26 errors. Their fielding percentage is currently at .978 which ranks 29th in the majors, and have 31 double plays.

Burke has thrown 52 innings and has racked up 47 K's so far in his career. His ERA is 3.63 (21 ER's allowed) and his WHIP is 1.231. He has surrendered 43 base knocks (7.4 hits per 9 innings) and has had 21 free passes. Burke (4-4 career record) is the owner of a FIP of 3.58 while he has faced 223 batters during his time in the major leagues.

The Kansas City Royals have a team on-base percentage of .297 in addition to a batting average of .237 for the season. They have been called out on strikes on 247 occasions (28th in baseball) and have earned a total of 275 base hits. Kansas City has 25 long balls for the season and 120 RBIs. The Royals have a team SLG% of .360 and they have an average of 3.43 runs per outing (27th in MLB). They have hit 60 doubles, while getting a free base 92 times and scoring 120 runs.

The Royals have a team WHIP of 1.200 in addition to having a FIP of 3.81 as a squad so far this year. Their strikeout to walk ratio sits at 8.00 (275 strikeouts vs 108 bases on balls). They come in at 9th in baseball as a pitching staff in total hits conceded with 264. They have surrendered 33 long balls and they relinquish 3.45 runs per 9 innings (4th in MLB). The Kansas City pitching staff have conceded 119 runs for the year while holding a team ERA of 3.16 (109 earned runs given up).

Kansas City has had relief pitchers step onto the hill in 15 save chances and they have walked away with 11 saves. They rank 8th in MLB holding a save rate of 73.3%, and they have sent 107 relief pitchers to the hill this year. Their relievers have come in 35 times in high leverage situations in addition to 26 occasions with base runners. Kansas City bullpen pitchers have an inherited score rate of 34.3% out of 35 inherited runners. Sitting with 35 save situations, the Royals have 20 holds and also 4 blown saves.

The Kansas City Royals have gotten 29 double plays and have accounted for a fielding rate of .990 (1st in the majors). The Royals have racked up 323 assists, 13 errors and have amassed 931 putouts during this campaign. In their 2,793 innings played, the Royals have accumulated a defensive efficiency of 72.1% (7th in baseball).

In his career, Lugo has given up 790 hits while he has accumulated 863 punch outs in 891 frames. He has allowed 333 ER's while earning a WHIP of 1.148 and being the owner of a FIP of 3.3. He has a strikeout to walk ratio of 3.70 and he has gone up against 3,658 opposing batters so far in his career. Lugo (59-43 career mark) has earned a 3.36 earned run average and has allowed 8.0 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (+125)

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