Chicago White Sox vs Minnesota Twins Prediction, 9/1/2025 MLB Picks, Best Bets & Odds

Game: Chicago White Sox vs Minnesota Twins

Date: Monday, September 1, 2025

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: Chicago (+120) Minnesota (-144)

The Chicago White Sox (48-86) are on their way to Target Field on Monday where they will compete against the Minnesota Twins (60-73). The moneyline on this game has the White Sox at +120 and the Twins are sitting at -144. The betting total is set at 9. The pitchers taking the mound will be Aaron Civale and Bailey Ober.

As a squad, the Chicago White Sox are putting up 3.9 runs per game, which ranks them 26th in baseball. They have accounted for 528 runs while holding a team on-base percentage of .302. The White Sox have hit 200 doubles as a unit and have smacked 134 baseballs out of the park. They have earned 509 RBI's as well as 1,035 hits this season, while their average at the plate is .233. Chicago has a slugging percentage of .373 and have been called out on strikes 1,106 times, while drawing a walk on 421 occasions.

Get all of our MLB Betting Picks

The White Sox are sitting with a team ERA of 4.23 so far this season (20th in the league), and the staff has rung up 1,021 batters. White Sox pitchers have relinquished 149 home runs and 611 runs (20th in baseball). They have walked 487 hitters and their FIP comes in at 4.46 as a team on the year. Chicago has relinquished 1,112 hits (8.6 per 9 innings) as well as 549 earned runs. They have a K/BB ratio of 2.10 and the pitching staff holds a WHIP of 1.37.

White Sox relief pitchers have entered the game with runners on base 129 times in addition to having 115 appearances in high leverage situations. The relief pitchers have earned 54 holds this year (28th in baseball). The White Sox relievers have a save rate of 45.9% and stepped onto the hill in 91 save situations. They have recorded 17 saves this season and have blown 20 out of their 37 save opportunities. The bullpen pitchers have inherited 191 base runners on the campaign with 32.5% of them ended up crossing the plate. The White Sox have sent 424 relievers to the hill this year.

The White Sox have converted 69.7% of balls in play into outs out of their 10,443 innings, which has them sitting 18th in professional baseball. The Chicago Cubs have earned 3,481 putouts this season, in addition to 1,079 assists and 82 errors. Their fielding rate is at .982 which is 27th in professional baseball, and they have turned 106 double plays.

Civale has pitched in 725 innings and has accumulated 651 strikeouts during his pro baseball career. Civale (42-44 career mark) is the owner of a FIP of 4.12 while facing 3,022 opposing hitters in the major leagues. His ERA is 4.18 (337 ER's allowed) and his WHIP is 1.222. He has given up 683 base knocks (8.5 hits per 9 innings) and has 203 walks.

The Twins have a slugging percentage of .398 and they score 4.18 runs per game (24th in MLB). They have recorded 204 two-baggers, while getting a free base 403 times and earning 556 runs. Minnesota has tallied 159 home runs this year to go along with 530 runs batted in. They have been rung up on 1,105 occasions (16th in the league) and have tallied 1,058 hits. The Minnesota Twins have earned an OBP of .310 as well as a team batting average of .238 on the campaign.

The Minnesota pitching staff have conceded 618 runs for the year while holding an ERA of 4.44 (577 earned runs conceded). They have allowed 159 dingers and they allow 4.75 runs per 9 innings (23rd in MLB). The Twins have a team WHIP of 1.307 in addition to having a FIP of 4.07 as a squad on the campaign. Their strikeout to walk ratio comes in at 8.60 (1,113 strikeouts against 368 bases on balls). They are currently ranked 24th in the league as a staff in total hits given up with 1,161.

Minnesota relief pitchers have an inherited score percentage of 35.7% out of 143 inherited base runners. Their bullpen pitchers have stepped onto the hill 155 times in high leverage situations and on 100 occasions with runners on. Sitting with 127 save situations, the Twins have earned 81 holds and 19 blown saves. They rank 25th in baseball holding a save rate of 56.8%, and they have sent 454 relief pitchers to the mound on the campaign. Minnesota has had bullpen pitchers step onto the hill in 44 save chances and they have tallied 25 saves.

The Minnesota Twins have gotten 80 double plays and have earned a fielding percentage of .987 (14th in the majors). The Twins have accrued 991 assists, 61 errors and have accumulated 3,510 putouts on the season. Out of their 10,530 innings played, the Twins have a defensive efficiency of 68.6% (27th in baseball).

During his MLB career, Ober has conceded 536 hits while accumulating 580 K's in 590 innings pitched. He has allowed 265 ER's while earning a WHIP of 1.124 and a FIP of 4.0. He has a K/BB ratio of 4.57 and he has gone up against 2,406 hitters thus far in his career. Ober (29-28 career win-loss mark) has earned a 4.04 earned run average and has surrendered 8.2 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Chicago (+120)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here