Cincinnati Reds vs Chicago Cubs Prediction, 5/31/2025 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs Chicago Cubs

Date: Saturday, May 31, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Cincinnati (+172) Chicago (-210)

The Cincinnati Reds (28-29) are headed to Wrigley Field on Saturday where they will attempt to defeat the Chicago Cubs (35-21). The odds on this game have Cincinnati at +172 while Chicago is coming in at -210. The over/under comes in at 9. The pitchers expected to start will be Nick Lodolo and Ben Brown.

The Reds have earned 100 doubles as a team and have knocked 58 balls out of the park. Cincinnati has a slugging percentage of .398 and have struck out 508 times, while being walked on 199 occasions. As a team, the Cincinnati Reds are knocking in 4.6 runs per game, which is 9th in MLB. They have 252 RBI's as well as 478 base knocks on the campaign, while their average at the plate is sitting at .248. They have tallied 264 runs scored while holding a team OBP of .323.

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Their strikeout to walk ratio is 2.66 and their pitching staff holds a collective WHIP of 1.20. Reds pitchers have allowed 65 home runs in addition to 232 runs in total (15th in baseball). Cincinnati has conceded 434 base hits (7.7 per 9 innings) as well as 212 earned runs. The Reds hold a team earned run average of 3.78 for the year (15th in MLB), and their staff has rung up 455 batters. Their pitching staff has walked 171 opposing hitters and their FIP is 4.09 as a unit for the season.

The Reds have dispatched 192 relievers to the mound for the year. The relief pitchers have inherited 62 runners on the year with 33.9% of those players ended up scoring. They have accumulated 15 saves on the season and have not converted 8 of their 23 save opportunities. The Reds relievers have earned a save rate of 65.2% and have entered the game in 65 save situations. The relievers have racked up 40 holds so far this season (3rd in the league). Reds relief pitchers have stepped onto the hill with players on base 39 times in addition to having 50 appearances in high leverage situations.

The Chicago White Sox are sitting with 1,515 putouts on the campaign, in addition to 436 assists and 26 errors. Their fielding rate sits at .987 which has them ranked 12th in baseball, and they have turned 30 double plays. The Reds have turned 72.4% of balls in play into outs out of 4,545 innings on the diamond, which has them ranked 4th in the majors.

Lodolo has pitched in 316 frames and is sitting with 355 punch outs in his pro baseball career. His earned run average is 4.30 (151 ER's allowed) and his WHIP is 1.256. He has conceded 299 base hits (8.5 hits per nine innings) and has 98 walks. Lodolo (19-18 career win-loss mark) sits with a FIP of 4.23 while he has faced 1,368 opposing hitters in the majors.

The Chicago Cubs hold an on-base percentage of .335 as well as a team batting average of .262 for the season. They have been called out on strikes on 441 instances (20th in the league) and have earned 512 hits. Chicago has compiled 79 HRs for the year and 322 runs batted in. The Cubs have a team slugging % of .450 and they tally 5.89 runs per outing (1st in baseball). They have recorded 105 doubles, while walking 212 times and scoring 330 runs.

The Chicago pitching staff have surrendered 235 runs for the year while holding an ERA of 3.89 (217 earned runs conceded). They have surrendered 63 homers and they concede 4.21 runs per 9 innings (15th in baseball). The Cubs have a WHIP of 1.276 with a FIP of 4.03 as a staff so far this year. Their K/BB ratio sits at 8.00 (449 strikeouts against 169 bases on balls). They sit at 21st in the league as a pitching staff in total hits conceded with 472.

Chicago bullpen pitchers hold an inherited score rate of 33.3% of 60 inherited base runners. Their relievers have come in 63 times in high leverage situations and on 43 occasions with runners on base. With 62 save situations, the Cubs have 39 holds in addition to 8 blown saves. They sit at 16th in the league holding a save rate of 63.6%, and they have sent 195 relievers onto the diamond on the season. Chicago has called on relievers to step onto the mound in 22 save chances and they have tallied 14 saves.

The Chicago Cubs have gotten 48 double plays and have accounted for a fielding rate of .986 (15th in MLB). The Cubs have accrued 476 assists, 28 errors and have accumulated 1,508 putouts for the year. In their 4,524 innings played, the Cubs hold a efficiency on defense of 69.9% (15th in baseball).

During his MLB career, Brown has allowed 104 base knocks while he has totaled 126 punch outs in 105 innings. Brown (4-6 career win-loss mark) holds a 4.96 earned run average while allowing 8.9 hits per 9 innings. He has given up a total of 58 earned runs while holding a WHIP of 1.339 and a FIP of 4.9. He has a K/BB ratio of 3.41 and he has gone up against 456 opposing hitters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Chicago (-210) and under 9 runs

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