Cincinnati Reds vs Houston Astros Prediction, 5/10/2025 MLB Picks, Best Bets & Odds
Game: Cincinnati Reds vs Houston Astros
Date: Saturday, May 10, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Cincinnati (+120) Houston (-144)
Daikin Park is the location where the Houston Astros (18-18) will take on the Cincinnati Reds (19-19) on Saturday. The odds on this game have Cincinnati at +120 while Houston opens at -144. The over/under has been set at 8.5. The pitchers taking the mound will be Brady Singer and Lance McCullers Jr..


As a squad, the Cincinnati Reds are scoring 4.8 runs per game, which has them sitting at 10th in the league. They have racked up 181 runs scored and hold an on-base percentage of .322. The Reds have hit 56 doubles as a unit and have hit 39 balls out of the stadium. They have recorded 174 runs batted in and 308 base knocks on the season, and their average at the plate sits at .242. Cincinnati is slugging .382 and have struck out 331 times, while taking a walk on 139 occasions.
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They have a K/BB ratio of 2.79 and the pitching staff holds a collective WHIP of 1.12. Reds pitchers have given up 47 long balls and 151 runs in total (13th in the league). Cincinnati has given up 263 hits (7.0 per 9 innings) as well as 134 earned runs. The Reds have an earned run average of 3.59 over the course of the season (9th in the league), and their staff has rung up 318 hitters. Their pitching staff has walked 114 opposing hitters and their FIP comes in at 4.16 as a squad for the season.
The Reds have sent 125 relievers to the mound this year. The relief pitchers have inherited 43 base runners over the course of the season with 30.2% of them crossed home plate. They have compiled 11 saves for the season and have not converted 5 of 16 chances to save the game. The Reds relievers have accumulated a save rate of 68.8% and have entered the game in 46 save situations. The relief pitchers are sitting with 29 holds over the course of the season (4th in the league). Reds relief pitchers have gone to the mound with runners on 28 times in addition to having 38 appearances in high leverage situations.
The Reds have transformed 74.3% of balls in play into outs out of 3,027 innings, which has them ranked 1st in baseball. The Chicago White Sox have a total of 1,009 putouts on the campaign, as well as 273 assists and 21 errors. Their fielding rate is at .984 which has them ranked 20th in professional baseball, and they have turned 16 double plays.
Singer (40-46 career mark) has a FIP of 4.19 while he has faced 3,096 hitters in the major leagues. He has surrendered 726 hits (9.0 hits per nine innings) and has 228 free passes. His earned run average is 4.25 (342 ER's allowed) and his career WHIP is 1.317. Singer has taken the ball for 724 frames and has tallied 683 strikeouts during his career.
Houston has a total of 31 home runs for the year to go along with 137 RBIs. They have recorded 48 doubles, while walking 114 times and putting up 145 runs. The Houston Astros have earned a team OBP of .313 and a team batting average of .241 on the campaign. The Astros have a team slugging percentage of .366 and they are scoring 4.03 runs per contest (18th in MLB). They have been called out on strikes on 282 instances (25th in MLB) and have totaled 287 base hits.
The Astros have a team WHIP of 1.133 and have a FIP of 3.48 as a pitching staff so far this season. Their K/BB ratio sits at 9.40 (330 strikeouts vs 107 bases on balls). They come in at 3rd in MLB as a staff in total hits conceded with 250. They have yielded 33 dingers and they surrender 3.68 runs per 9 innings (5th in MLB). The Houston pitching staff have allowed 129 runs this year while having an ERA of 3.37 (118 earned runs yielded).
Houston relief pitchers hold an inherited score rate of 28.2% out of 39 inherited runners. Their relief pitchers have stepped onto the mound 29 times in high leverage situations and on 27 occasions with base runners. Sitting with 36 save situations, the Astros have 23 holds and also 4 blown saves. They rank 8th in baseball with a save percentage of 69.2%, and they have sent 114 relievers to the hill so far this season. Houston has called on relievers to take the mound in 13 save opportunities and they have come away with 9 saves.
In their 2,841 innings played, the Astros hold a defensive efficiency of 72.2% (4th in MLB). The Houston Astros have turned 20 double plays and own a fielding percentage of .989 (6th in pro baseball). The Astros have recorded 272 assists, 14 errors and have a total of 947 putouts on the campaign.
During his pro baseball career, McCullers has allowed 606 base hits while he has totaled 804 punch outs in 721 innings pitched. McCullers (49-32 career record) has a 3.47 earned run average while giving up 7.6 hits per 9 innings. He has conceded 278 earned runs while holding a WHIP of 1.255 and being the owner of a FIP of 3.4. He has a strikeout to walk ratio of 2.69 and he has faced 3,035 batters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Houston (-144)
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Additional Resources:
Houston Astros - Twitter
Cincinnati Reds - Twitter