Cincinnati Reds vs Houston Astros Prediction, 5/11/2025 MLB Picks, Best Bets & Odds
Game: Cincinnati Reds vs Houston Astros
Date: Sunday, May 11, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Cincinnati (+120) Houston (-144)
The Cincinnati Reds (19-20) are hitting the road to Daikin Park on Sunday where they will play the Houston Astros (18-18). The moneyline on this matchup has the Reds at +120 and the Astros are priced at -144. The total is 8.5. The starting pitchers are Andrew Abbott and Ronel Blanco.


Cincinnati has a slugging rate of .383 and have been called out on strikes 342 times, while being walked on 143 occasions. They have recorded 178 RBI's in addition to 318 base knocks for the year, while their team batting average is sitting at .242. The Reds have accounted for 60 two-baggers as a team and have smacked 40 baseballs out of the stadium. They have racked up 185 runs scored and have an OBP of .322. As a unit, the Cincinnati Reds are notching 4.7 runs per outing, which puts them at 11th in MLB.
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They have earned a strikeout to walk ratio of 2.82 and the pitching staff holds a collective WHIP of 1.12. Reds pitchers have yielded 47 home runs and 156 runs (14th in baseball). Cincinnati has conceded 273 base hits (7.1 per 9 innings) as well as 138 earned runs. The Reds hold a team earned run average of 3.58 on the campaign (9th in baseball), and the staff has rung up 330 batters. They have walked 117 opposing hitters and their FIP comes in at 4.10 as a unit for the season.
Reds pitchers have entered the game with opponents on base 30 times as well as having 42 appearances in high leverage situations. The relievers have notched 29 holds so far this year (4th in MLB). The Reds relief pitchers have earned a save percentage of 64.7% and have come into the game in 47 save situations. They have earned 11 saves on the year and have not converted 6 out of their 17 save opportunities. The relief pitchers have inherited 43 runners so far this year and 30.2% of those runners crossed home plate. The Reds have sent 129 relief pitchers to the mound this season.
The Chicago White Sox are sitting with 1,041 putouts on the campaign, in addition to 284 assists and 22 errors. Their fielding percentage is holding at .984 which puts them in 21st in professional baseball, and have a total of 16 double plays. The Reds have turned 74.0% of baseballs in play into outs out of 3,123 innings on the field, which has them sitting at 1st in pro baseball.
Abbott has taken the ball for 271 frames and has 265 K's during his MLB career. His ERA is 3.65 (110 earned runs allowed) and his WHIP is 1.295. He has conceded 243 hits (8.1 hits per nine innings) and has 108 walks. Abbott (20-16 career record) sits with a FIP of 3.60 while going up against 1,143 opposing batters during his time in the major leagues.
The Houston Astros have earned a team OBP of .313 and a batting average of .241 on the season. They have been called out on strikes on 282 occasions (25th in MLB) and have totaled 287 base hits. Houston has a total of 31 home runs for the season to go along with 137 RBIs. The Astros have a team slugging percentage of .366 and they score 4.03 runs per game (19th in baseball). They have recorded 48 two-baggers, while getting a free base 114 times and recording 145 runs.
The Astros have a team WHIP of 1.133 and have a FIP of 3.50 as a pitching staff for the year. They rank 3rd in baseball as a pitching staff in total hits relinquished with 250. The Houston pitching staff have surrendered 129 runs on the season while having an ERA of 3.37 (118 earned runs yielded). Their strikeout to walk ratio comes in at 9.40 (330 strikeouts vs 107 walks). They have allowed 33 dingers and they concede 3.68 runs per 9 innings (5th in MLB).
Sitting with 36 save situations, the Astros have compiled 23 holds and also 4 blown saves. Houston has called on relievers to step onto the hill in 13 save chances and they have earned 9 saves. Their bullpen pitchers have taken the field 29 times in high leverage situations and on 27 occasions with runners on. Houston bullpen pitchers hold an inherited score rate of 28.2% out of their 39 inherited runners. They rank 8th in baseball with a save percentage of 69.2%, and they have sent 114 relievers onto the field so far this season.
The Houston Astros have gotten 20 double plays and have a fielding rate of .989 (7th in pro baseball). The Astros have racked up 272 assists, 14 errors and are sitting with 947 putouts on the season. In 2,841 innings on the diamond, the Astros have earned a defensive efficiency of 72.2% (5th in professional baseball).
So far in his pro baseball career, Blanco has surrendered 201 base hits while earning 257 K's in 259 innings. He has conceded 102 ER's while holding a WHIP of 1.223 and a FIP of 3.5. He has a K/BB ratio of 2.22 and he has gone up against 1,080 batters so far in his MLB career. Blanco (17-10 career record) has a 3.54 ERA while allowing 7.0 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Houston (-144)
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Additional Resources:
Houston Astros - Twitter
Cincinnati Reds - Twitter