Cincinnati Reds vs Kansas City Royals Prediction, 5/28/2025 MLB Picks, Best Bets & Odds

Game: Cincinnati Reds vs Kansas City Royals

Date: Wednesday, May 28, 2025

Location: Kauffman Stadium in Kansas City, MO

TV: FanDuel Sports Network Kansas City

Odds/Point Spread: Cincinnati (+125) Kansas City (-150)

Kauffman Stadium is the location where the Kansas City Royals (29-26) will attempt to beat the Cincinnati Reds (27-28) on Wednesday. The line on this contest has the Reds at +125 while the Royals are opening at -150. The betting total is set at 8.5. The pitchers expected to start will be Hunter Greene and Noah Cameron.

Cincinnati has a slugging % of .397 and have struck out 492 times, while taking a walk on 191 occasions. They have accounted for 244 runs batted in as well as 459 hits over the course of the season, and their team batting average is at .247. The Reds have tallied 98 two-baggers as a team and have knocked 55 baseballs out of the stadium. They are sitting with 255 runs scored while holding a team on-base percentage of .322. As a team, the Cincinnati Reds are notching 4.6 runs per game, which has them sitting at 9th in the league.

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The Reds are sitting with a team ERA of 3.82 this season (15th in the league), and they have rung up 445 batters. Reds pitchers have given up 65 home runs and also 227 runs in total (15th in MLB). Their pitching staff has walked 166 players from the other team and their FIP sits at 4.13 as a squad this year. Cincinnati has surrendered 418 base hits (7.7 per 9 innings) and also 207 earned runs. Their strikeout to walk ratio is 2.68 and their pitching staff has a collective WHIP of 1.20.

The Reds have sent 187 relief pitchers to the mound so far this season. The relief pitchers have inherited 62 runners on the campaign with 33.9% of those runners ended up scoring. They have compiled 15 saves over the course of the season and have blown 8 of their 23 chances to get a save. The Reds relief pitchers have compiled a save rate of 65.2% and have entered the game in 65 save situations. The bullpen have a total of 40 holds this season (2nd in MLB). Reds relief pitchers have gone to the mound with opponents on base 39 times and also have had 50 appearances in high leverage situations.

The Chicago White Sox have a total of 1,464 putouts at this point in the season, in addition to 421 assists and 26 errors. Their fielding rate is holding steady at .986 which is 15th in MLB, and have a total of 29 double plays. The Reds have turned 72.5% of balls in play into outs out of 4,392 innings, ranking them 2nd in the majors.

Greene has taken the mound for 437 innings and has earned 548 strikeouts in his MLB career. His ERA is 3.75 (182 ER's allowed) and he has a WHIP of 1.157. He has surrendered 343 base knocks (7.1 hits per nine innings) with 163 walks. Greene (22-27 record in his career) holds a FIP of 3.69 while going up against 1,833 hitters in the major leagues.

The Kansas City Royals hold a team OBP of .300 as well as a team batting average of .246 this year. They have struck out on 388 occasions (28th in the league) and have earned a total of 453 base knocks. Kansas City has 33 home runs on the season as well as 180 runs batted in. The Royals have a SLG% of .363 and they average 3.33 runs per outing (27th in MLB). They have hit 95 doubles, while getting a free base 131 times and scoring 183 runs.

The Kansas City pitching staff have conceded 184 runs over the course of the season while holding a team ERA of 3.10 (169 earned runs yielded). They have conceded 50 homers and they give up 3.38 runs per 9 innings (2nd in the league). The Royals have a team WHIP of 1.179 and are the owners of a FIP of 3.61 as a unit on the season. Their K/BB ratio comes in at 8.10 (442 strikeouts vs 150 free passes). They have a ranking of 13th in the league as a staff in total hits surrendered with 428.

Kansas City relief pitchers have an inherited score percentage of 27.0% out of their 63 inherited base runners. Their relievers have stepped onto the hill 61 times in high leverage situations and also on 50 occasions with base runners. With 48 save situations, the Royals have compiled 27 holds in addition to 4 blown saves. They are currently ranked 1st in MLB holding a save rate of 81.0%, and they have dispatched 171 bullpen pitchers onto the field over the course of the season. Kansas City has called on relievers to enter the contest in 21 save chances and they have walked away with 17 saves.

Out of their 4,413 innings played, the Royals have accumulated a defensive efficiency of 71.1% (10th in professional baseball). The Kansas City Royals have turned 50 double plays and hold a fielding percentage of .989 (5th in professional baseball). The Royals have recorded 500 assists, 22 errors and have amassed 1,471 putouts this year.

During his MLB career, Cameron has conceded 7 hits while earning 14 K's in 19 frames. He has given up a total of 2 ER's while earning a WHIP of 0.681 and being the owner of a FIP of 0.9. He has a K/BB ratio of 2.33 and he has faced 71 opposing hitters so far in his MLB career. Cameron (1-1 career win-loss record) has earned a 0.94 earned run average and has conceded 3.3 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Kansas City (-150)

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