Cincinnati Reds vs Pittsburgh Pirates Prediction, 5/19/2025 MLB Picks, Best Bets & Odds
Game: Cincinnati Reds vs Pittsburgh Pirates
Date: Monday, May 19, 2025
Location: PNC Park in Pittsburgh, PA
TV: SportsNet Pittsburgh
Odds/Point Spread: Cincinnati (-122) Pittsburgh (+102)
The Cincinnati Reds (21-24) are headed to PNC Park on Monday where they will take on the Pittsburgh Pirates (15-29). The line on this contest has Cincinnati at -122 while Pittsburgh is opening at +102. The over/under is set at 9. The expected starting pitchers will be Nick Lodolo and Mitch Keller.


As a unit, the Cincinnati Reds are scoring 4.6 runs per game, which puts them at 13th in baseball. They have racked up 208 runs and hold an on-base percentage of .319. The Reds have earned 74 two-baggers as a squad and have hit 47 baseballs out of the stadium. They have recorded 201 runs batted in and 362 hits this season, while their batting average is sitting at .239. Cincinnati has a slugging % of .385 and have been called out on strikes 403 times, while taking a walk on 164 occasions.
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They have accumulated a K/BB ratio of 2.75 and their pitching staff has recorded a WHIP of 1.18. Reds pitchers have conceded 52 home runs and also 184 runs in total (14th in the league). Cincinnati has conceded 332 base hits (7.5 per 9 innings) and also 164 earned runs. The Reds have compiled a team ERA of 3.69 on the campaign (10th in the league), and they have rung up 380 hitters. Their pitching staff has walked 138 opposing batters and their FIP comes in at 4.04 as a squad so far this season.
The Reds have dispatched 149 relievers to the hill this year. The relievers have inherited 51 base runners over the course of the season with 31.4% of those runners crossed home plate. They have tallied 11 saves so far this season and have blown 6 of 17 chances to get a save. The Reds relief pitchers have compiled a save rate of 64.7% and have stepped onto the mound in 48 save situations. The bullpen have a total of 29 holds this season (7th in MLB). Reds bullpen pitchers have come into the game with runners on base 33 times in addition to having 43 appearances in high leverage situations.
The Reds have turned 72.8% of balls in play into outs out of 3,600 innings on the field, which has them sitting 1st in baseball. The Chicago White Sox are sitting with 1,200 putouts on the campaign, as well as 339 assists and 23 errors. Their fielding percentage is holding at .985 which has them sitting 19th in professional baseball, and they have turned 19 double plays.
Lodolo has taken the hill for 305 innings and has earned 342 strikeouts thus far in his career. His earned run average is 4.33 (147 earned runs allowed) and his career WHIP is 1.258. He has surrendered 289 hits (8.5 hits per nine innings) and has had 95 walks. Lodolo (18-18 record in his career) has earned a FIP of 4.27 while he has gone up against 1,321 batters in the majors.
The Pirates have a team slugging percentage of .328 and they earn 3.07 runs per contest (30th in the league). They have tallied 50 two-baggers, while getting a free base 156 times and scoring 135 runs. Pittsburgh has accounted for 31 HRs on the season to go along with 132 runs batted in. They have been rung up on 381 instances (7th in MLB) and have totaled 321 base hits. The Pittsburgh Pirates have compiled an OBP of .301 in addition to a team batting average of .220 for the year.
The Pirates are sitting with a team WHIP of 1.260 and are the owners of a FIP of 3.92 as a pitching staff on the campaign. They have earned a strikeout to walk ratio of 7.40 (324 strikeouts vs 141 walks). They come in at 17th in baseball as a pitching staff in total hits given up with 354. They have conceded 38 home runs and they concede 4.33 runs per 9 innings (15th in the league). The Pittsburgh pitching staff have allowed 189 runs on the year while holding a team ERA of 4.01 (175 earned runs conceded).
With 40 save situations, the Pirates have 23 holds and 8 blown saves. Pittsburgh has had relievers enter the contest in 16 save chances and they have come away with 8 saves. Their relievers have taken the field 47 times in high leverage situations in addition to 44 occasions with base runners. Pittsburgh relievers hold an inherited score percentage of 33.8% out of their 68 inherited runners. They sit at 27th in the league holding a save percentage of 50.0%, and they have dispatched 147 relief pitchers onto the field for the year.
The Pittsburgh Pirates have gotten 41 double plays and have a fielding percentage of .983 (23rd in the majors). The Pirates have 394 assists, 28 errors and have a total of 1,179 putouts so far this season. In their 3,537 innings on the field, the Pirates have accumulated a defensive efficiency of 70.5% (12th in MLB).
Keller (37-55 career mark) has a 4.56 ERA and has allowed 9.5 hits per 9 innings. He has a K/BB ratio of 2.77 and he has faced 3,295 opposing hitters thus far in his career. He has surrendered 382 earned runs while holding a WHIP of 1.407 and a FIP of 4.5. In his pro baseball career, Keller has allowed 796 base hits while he has tallied 730 K's in 753 frames.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Cincinnati (-122)
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Additional Resources:
Pittsburgh Pirates - Twitter
Cincinnati Reds - Twitter