Cleveland Guardians vs Chicago White Sox Prediction, 7/12/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Chicago White Sox

Date: Saturday, July 12, 2025

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Cleveland (-152) Chicago (+126)

The Cleveland Guardians (43-48) are hitting the road to Rate Field on Saturday where they will meet the Chicago White Sox (31-62). The odds on this game have Cleveland at -152 and Chicago is sitting at +126. The betting total comes in at 9. The men taking the mound will be Tanner Bibee and Sean Burke.

As a unit, the Cleveland Guardians are knocking in 3.7 runs per contest, which is 26th in baseball. They have racked up 333 runs while holding a team on-base percentage of .295. The Guardians have tallied 128 doubles as a unit and have knocked 92 baseballs out of the stadium. They have 318 runs batted in as well as 665 hits on the campaign, and their team batting average comes in at .224. Cleveland has a slugging rate of .366 and have struck out 744 times, while taking a walk on 281 occasions.

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The Guardians have an earned run average of 3.97 on the year (18th in the league), and they have rung up 767 hitters. Guardians pitchers have surrendered 95 home runs and also 384 total runs (15th in baseball). They have walked 335 opposing hitters and their FIP sits at 4.08 as a unit on the year. Cleveland has conceded 756 base hits (8.5 per 9 innings) and 355 earned runs. Their strikeout to walk ratio is 2.29 and the pitching staff holds a collective WHIP of 1.36.

The Guardians relievers have recorded a save rate of 71.4% and have stepped onto the mound in 100 save situations. The relievers have inherited 112 runners for the year with 38.4% of those players crossed home plate. Guardians relief pitchers have come into the game with runners on 79 times and also have had 95 appearances in high leverage situations. The Guardians have sent 306 relief pitchers to the hill this year. The relievers are sitting with 64 holds for the year (4th in the league). They have recorded 25 saves this season and have blown 10 out of their 35 chances to save the game.

The Cincinnati Reds are sitting with 2,415 putouts so far this season, as well as 730 assists and 65 errors. Their fielding percentage is at .980 which has them sitting 28th in baseball, and have a total of 69 double plays. The Guardians have turned 68.5% of baseballs in play into outs out of 7,245 innings on the diamond, which ranks them 24th in baseball.

Bibee has taken the mound for 418 innings and has totaled 418 K's in his MLB career. His ERA is 3.53 (164 ER's allowed) and he has a career WHIP of 1.167. He has given up 368 hits (7.9 hits per nine innings) and has had 120 free passes. Bibee (26-21 career win-loss mark) has earned a FIP of 3.48 while he has gone up against 1,729 hitters in the majors.

The Chicago White Sox have accumulated an OBP of .296 as well as a batting average of .222 so far this year. They have been called out on strikes on 794 occasions (12th in the league) and have tallied 672 hits. Chicago has accounted for 71 home runs this season and 303 runs batted in. The White Sox hold a team slugging percentage of .345 and they are earning 3.42 runs per game (28th in the league). They have 142 doubles, while taking a walk 301 times as well as putting up 318 runs.

The White Sox hold a team WHIP of 1.396 with a FIP of 4.52 as a unit over the course of the season. They come in at 21st in the league as a pitching staff in total hits conceded with 785. The Chicago pitching staff have yielded 410 runs so far this season while having an ERA of 4.14 (370 earned runs relinquished). They have earned a K/BB ratio of 7.40 (659 strikeouts vs 338 walks). They have conceded 100 home runs and they allow 4.59 runs per 9 innings (22nd in MLB).

Chicago has called on bullpen pitchers to enter the game in 27 save chances and they have tallied 12 saves. They rank 30th in MLB with a save rate of 44.4%, and they have sent 287 bullpen pitchers to the hill on the year. Their relief pitchers have taken the field 82 times in high leverage situations and on 83 occasions with runners on base. Chicago bullpen pitchers hold an inherited score percentage of 28.9% out of 121 inherited runners. Sitting with 69 save situations, the White Sox have recorded 42 holds and also 15 blown saves.

The Chicago White Sox have gotten 80 double plays and have notched a fielding percentage of .983 (26th in pro baseball). The White Sox have accrued 768 assists, 56 errors and have 2,414 putouts on the season. In 7,242 innings on the diamond, the White Sox hold a defensive efficiency of 69.5% (18th in pro baseball).

During his career, Burke has surrendered 102 hits while he has earned 97 strikeouts in 111 innings pitched. He has surrendered a total of 48 ER's while earning a WHIP of 1.351 and having a FIP of 3.8. His strikeout to walk ratio is 2.02 and he has gone up against 480 batters so far in his MLB career. Burke (6-8 career mark) holds a 3.89 earned run average and has given up 8.3 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+126)

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