Cleveland Guardians vs Detroit Tigers Prediction, 9/17/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Detroit Tigers

Date: Wednesday, September 17, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: Cleveland (+110) Detroit (-130)

The Cleveland Guardians (78-71) are traveling to Comerica Park on Wednesday where they will meet the Detroit Tigers (85-65). The odds on this game have the Guardians at +110 and the Tigers are opening at -130. The total comes in at 9. The expected starting pitchers will be Logan Allen and Jack Flaherty.

Cleveland has a slugging rate of .370 and have struck out 1,224 times, while drawing a walk on 452 occasions. They have amassed 560 RBI's as well as 1,095 hits for the season, while their team batting average sits at .225. The Guardians have earned 216 doubles as a team and have hit 154 baseballs out of the stadium. They have earned 580 runs scored and have an on-base percentage of .296. As a squad, the Cleveland Guardians are scoring 3.9 runs per contest, which is 27th in MLB.

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They have earned a K/BB ratio of 2.49 and their pitching staff holds a collective WHIP of 1.29. Guardians pitchers have relinquished 157 long balls in addition to 611 runs in total (7th in MLB). Cleveland has allowed 1,206 hits (8.2 per 9 innings) as well as 558 earned runs. The Guardians have an earned run average of 3.79 on the season (6th in MLB), and they have rung up 1,236 hitters. They have walked 497 players from the other team and their FIP comes in at 4.06 as a team this year.

Guardians bullpen pitchers have entered the contest with runners on base 135 times and also have had 174 appearances in high leverage situations. The relief pitchers have notched 98 holds on the season (5th in the league). The Guardians relievers have recorded a save rate of 70.3% and have entered the game in 165 save situations. They have 45 saves on the season and have blown 19 of their 64 save opportunities. The bullpen pitchers have inherited 188 runners for the season and 33.5% of those runners ended up crossing the plate. The Guardians have sent 486 relief pitchers to the hill on the campaign.

The Guardians have transformed 69.7% of balls hit into play into outs in their 11,916 innings, which ranks them 19th in pro baseball. The Cincinnati Reds have 3,972 putouts at this point in the season, in addition to 1,231 assists and 91 errors. Their fielding rate is holding at .983 which ranks 27th in the majors, and they have turned 114 double plays.

Allen has taken the ball for 366 frames and has accounted for 309 strikeouts so far in his career. Allen (22-24 record in his career) has earned a FIP of 4.48 and he has gone up against 1,597 batters in the majors. His ERA is 4.55 (185 earned runs allowed) and he has a WHIP of 1.463. He has given up 388 base knocks (9.5 hits per 9 innings) and has had 148 free passes.

Detroit has accumulated 187 home runs this season as well as 695 RBIs. They have tallied 232 two-baggers, while walking 473 times and recording 729 runs. The Detroit Tigers have accumulated an OBP of .318 and a batting average of .249 so far this year. The Tigers hold a team slugging percentage of .420 and they score 4.86 runs per game (8th in MLB). They have struck out on 1,323 occasions (6th in the league) and have recorded 1,259 hits.

The Detroit pitching staff have given up 634 runs this season while holding an ERA of 3.91 (578 earned runs relinquished). They have allowed 174 long balls and they allow 4.29 runs per 9 innings (12th in the league). The Tigers are sitting with a team WHIP of 1.238 in addition to having a FIP of 4.07 as a unit for the year. Their K/BB ratio is 8.50 (1,264 strikeouts against 442 free passes). They are currently ranked 13th in the league as a pitching staff in total hits conceded with 1,206.

Detroit has called on bullpen pitchers to step onto the hill in 58 save opportunities and they have earned 38 saves. They are currently ranked 9th in the league holding a save rate of 65.5%, and they have dispatched 461 relievers to the hill on the year. Their relievers have stepped onto the mound 129 times in high leverage situations and also on 163 occasions with base runners. Detroit relievers have an inherited score rate of 28.6% of 231 inherited runners. Sitting with 132 save situations, the Tigers have accumulated 70 holds in addition to 20 blown saves.

Out of their 11,979 innings played, the Tigers have accumulated a defensive efficiency of 70.3% (13th in baseball). The Detroit Tigers have gotten 123 double plays and have a fielding percentage of .986 (16th in MLB). The Tigers have accrued 1,290 assists, 75 errors and have earned a total of 3,993 putouts this year.

So far in his pro baseball career, Flaherty has given up 828 base knocks and he has 1,120 strikeouts in 980 innings. Flaherty (63-54 career mark) is the owner of a 3.80 earned run average while giving up 7.6 hits per nine innings. He has given up a total of 414 earned runs while holding a WHIP of 1.198 and a FIP of 3.7. He has a strikeout to walk ratio of 3.23 and he has gone up against 4,079 opposing batters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Cleveland (+110)

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