Cleveland Guardians vs Minnesota Twins Prediction, 5/20/2025 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs Minnesota Twins
Date: Tuesday, May 20, 2025
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: Cleveland (+110) Minnesota (-130)
The Cleveland Guardians (25-21) are headed to Target Field on Tuesday where they will attempt to defeat the Minnesota Twins (26-21). The moneyline on this contest has the Guardians at +110 while the Twins open at -130. The total is 8.5. The pitchers who are expected to start are Gavin Williams and Chris Paddack.


The Guardians have hit 60 two-baggers as a unit and have hit 51 baseballs out of the stadium. Cleveland has a slugging rate of .380 and have been rung up 360 times, while taking a walk on 149 occasions. As a team, the Cleveland Guardians are putting up 4.0 runs per game, which puts them at 22nd in the league. They have 171 runs batted in and 346 base knocks this year, while their average at the plate sits at .233. They have earned a total of 182 runs scored and hold an OBP of .307.
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They have earned a K/BB ratio of 2.35 and the pitching staff has recorded a WHIP of 1.41. Guardians pitchers have given up 53 home runs and also 202 runs (17th in the league). Cleveland has relinquished 403 hits (9.0 per 9 innings) as well as 186 earned runs. The Guardians have compiled a team earned run average of 4.14 for the year (18th in the league), and the staff has struck out 392 hitters. They have walked 167 opposing batters and their FIP sits at 4.17 as a squad on the year.
Guardians pitchers have entered the game with opponents on base 38 times in addition to having 44 appearances in high leverage situations. The relief pitchers have accumulated 38 holds so far this season (2nd in the league). The Guardians bullpen have earned a save rate of 73.7% and stepped onto the hill in 57 save situations. They have compiled 14 saves on the campaign and have not converted 5 out of their 19 chances to save the game. The bullpen pitchers have inherited 55 runners on the season with 32.7% of them crossed home plate. The Guardians have dispatched 158 relief pitchers to the mound this season.
The Cincinnati Reds have 1,212 putouts so far this season, in addition to 346 assists and 30 errors. Their fielding percentage sits at .981 which has them ranked 27th in baseball, and they have turned 37 double plays. The Guardians have converted 67.2% of baseballs in play into outs out of their 3,636 innings on the diamond, which has them ranked 27th in MLB.
Williams (9-17 career win-loss mark) is the owner of a FIP of 4.03 while he has gone up against 864 hitters during his time in the majors. He has given up 183 base hits (8.2 hits per nine innings) and has had 93 free passes. His ERA is 4.10 (91 earned runs allowed) and he has a career WHIP of 1.380. Williams has taken the ball for 200 frames and has 211 punch outs so far in his pro baseball career.
The Minnesota Twins have accumulated an on-base percentage of .310 and a batting average of .242 on the campaign. They have been rung up on 385 occasions (18th in the league) and have recorded 380 base knocks. Minnesota is sitting with 45 home runs on the year to go along with 185 runs batted in. The Twins have a team SLG% of .386 and they earn 4.13 runs per game (19th in MLB). They have recorded 78 doubles, while getting a free base 132 times as well as racking up 194 runs.
The Twins hold a team WHIP of 1.139 and are the owners of a FIP of 3.41 as a pitching staff so far this year. They are sitting at 6th in baseball as a staff in total hits allowed with 351. The Minnesota pitching staff have allowed 159 runs for the season and come in with a team ERA of 3.20 (146 earned runs relinquished). Their K/BB ratio is 9.20 (421 strikeouts against 116 free passes). They have yielded 43 home runs and they give up 3.49 runs per 9 innings (3rd in the league).
Sitting with 59 save situations, the Twins have amassed 38 holds and 7 blown saves. Minnesota has had bullpen pitchers step onto the mound in 19 save opportunities and they have recorded 12 saves. Their bullpen pitchers have taken the field 56 times in high leverage situations and also on 33 occasions with runners on base. Minnesota relievers have an inherited score percentage of 34.0% out of their 47 inherited base runners. They rank 17th in MLB holding a save rate of 63.2%, and they have dispatched 161 relievers onto the diamond for the year.
The Minnesota Twins have turned 25 double plays and own a fielding percentage of .984 (22nd in MLB). The Twins have racked up 326 assists, 26 errors and have a total of 1,231 putouts this year. In their 3,693 innings on the field, the Twins are sitting with a defensive efficiency of 70.3% (14th in pro baseball).
In his pro baseball career, Paddack has conceded 453 base hits while he has accumulated 450 K's in 469 innings pitched. Paddack (29-27 career record) holds a 4.35 ERA and has conceded 8.7 hits per nine innings. He has conceded 227 ER's while earning a WHIP of 1.191 and having a FIP of 4.3. He has a K/BB ratio of 4.25 and he has gone up against 1,964 hitters so far in his career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Cleveland (+110)
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Additional Resources:
Minnesota Twins - Twitter
Cleveland Guardians - Twitter