Cleveland Guardians vs New York Yankees Prediction, 6/4/2025 MLB Picks, Best Bets & Odds
Game: Cleveland Guardians vs New York Yankees
Date: Wednesday, June 4, 2025
Location: Yankee Stadium in Bronx, NY
TV: YES
Odds/Point Spread: Cleveland (+125) New York (-145)
The Cleveland Guardians (32-26) are en route to Yankee Stadium on Wednesday where they will play the New York Yankees (36-22). The moneyline on this contest has the Guardians at +125 while the Yankees open at -145. The total is 8.5. The pitchers taking the mound will be Luis Ortiz and Clarke Schmidt.


As a team, the Cleveland Guardians are scoring 4.1 runs per outing, which has them sitting at 23rd in baseball. They have accumulated 235 runs while holding a team on-base percentage of .308. The Guardians have hit 81 two-baggers as a team and have knocked 61 baseballs out of the stadium. They have earned 222 RBI's and 443 hits on the year, and their batting average comes in at .234. Cleveland is slugging .380 and have been rung up 461 times, while drawing a walk on 188 occasions.
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Their strikeout to walk ratio is 2.32 and the pitching staff has recorded a WHIP of 1.39. Guardians pitchers have surrendered 64 home runs and 251 runs in total (15th in MLB). Cleveland has yielded 494 hits (8.7 per 9 innings) as well as 231 earned runs. The Guardians hold a team earned run average of 4.06 on the season (21st in the league), and the staff has struck out 502 batters. They have walked 216 players from the other team and their FIP is 4.10 as a unit this year.
Guardians relief pitchers have stepped onto the hill with runners on 48 times in addition to having 53 appearances in high leverage situations. The bullpen have notched 45 holds on the season (3rd in the league). The Guardians bullpen have earned a save percentage of 78.3% and have entered the game in 69 save situations. They have recorded 18 saves on the year and have blown 5 of 23 save chances. The bullpen pitchers have inherited 69 base runners for the year and 33.3% of those players crossed home plate. The Guardians have dispatched 201 relief pitchers to the mound this year.
The Cincinnati Reds have notched a total of 1,535 putouts at this point in the season, as well as 440 assists and 37 errors. Their fielding percentage is holding at .982 which has them ranked 26th in pro baseball, and have 44 double plays. The Guardians have turned 67.8% of balls hit into play into outs out of 4,605 innings on the field, which has them ranked 25th in baseball.
Ortiz has pitched in 297 frames and has racked up 247 strikeouts thus far in his career. Ortiz (14-19 record in his career) has earned a FIP of 3.97 while he has faced 1,283 opposing batters during his time in the majors. His ERA is 4.03 (133 earned runs allowed) and his WHIP is 1.349. He has surrendered 271 base hits (8.2 hits per 9 innings) and has 130 walks.
The Yankees hold a slugging percentage of .468 and they score 5.50 runs per game (3rd in baseball). They have tallied 107 doubles, while taking a walk 240 times as well as notching 319 runs. New York has 95 home runs on the year to go along with 306 runs batted in. They have struck out on 512 occasions (9th in the league) and have notched a total of 511 base knocks. The New York Yankees have earned an OBP of .345 in addition to a batting average of .259 on the year.
The Yankees hold a team WHIP of 1.186 and have a FIP of 3.59 as a squad so far this season. They are sitting at 1st in the league as a pitching staff in total hits conceded with 410. The New York pitching staff have conceded 221 runs so far this season while having a team ERA of 3.60 (205 earned runs surrendered). Their K/BB ratio comes in at 9.60 (547 strikeouts vs 197 walks). They have yielded 56 long balls and they concede 3.88 runs per 9 innings (9th in the league).
Sitting with 60 save situations, the Yankees have earned 35 holds and also 7 blown saves. New York has called on bullpen pitchers to step onto the hill in 24 save opportunities and they have walked away with 17 saves. Their bullpen pitchers have stepped onto the mound 59 times in high leverage situations and on 61 occasions with runners on base. New York relievers hold an inherited score percentage of 23.7% out of their 93 inherited base runners. They rank 5th in the league with a save percentage of 70.8%, and they have sent 191 relief pitchers to the mound for the season.
The New York Yankees have turned 33 double plays and have a fielding percentage of .988 (11th in pro baseball). The Yankees have 480 assists, 25 errors and have 1,536 putouts during this campaign. In 4,608 innings on the diamond, the Yankees have earned a defensive efficiency of 71.8% (4th in pro baseball).
In his pro baseball career, Schmidt has conceded 339 base hits while he has totaled 353 punch outs in 357 frames. He has given up a total of 157 earned runs while holding a WHIP of 1.310 and a FIP of 3.9. He has a strikeout to walk ratio of 2.74 and he has faced 1,533 opposing hitters thus far in his career. Schmidt (21-22 career mark) has a 3.95 ERA while giving up 8.5 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Cleveland (+125)
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Additional Resources:
New York Yankees - Twitter
Cleveland Guardians - Twitter