Cleveland Guardians vs Tampa Bay Rays Prediction, 9/4/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs Tampa Bay Rays

Date: Thursday, September 4, 2025

Location: George M. Steinbrenner Field in Tampa, FL

TV: FanDuel Sports Network Sun

Odds/Point Spread: Cleveland (+110) Tampa Bay (-132)

The Tampa Bay Rays (69-69) will take on the Cleveland Guardians (68-69) at George M. Steinbrenner Field on Thursday. The odds on this game have Cleveland at +110 while Tampa Bay is coming in at -132. The betting total comes in at 9. The pitchers taking the mound will be Logan Allen and Ryan Pepiot.

The Guardians have recorded 194 two-baggers as a squad and have hit 142 baseballs out of the stadium. Cleveland has a slugging percentage of .368 and have struck out 1,129 times, while being walked on 416 occasions. As a team, the Cleveland Guardians are notching 3.9 runs per game, which ranks them 27th in baseball. They have amassed 511 RBI's and 1,001 hits for the year, while their team batting average is at .223. They have earned 530 runs scored while holding a team OBP of .294.

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They have earned a K/BB ratio of 2.40 and their pitching staff has earned a collective WHIP of 1.32. Guardians pitchers have conceded 152 home runs and also 591 runs in total (13th in the league). Cleveland has surrendered 1,133 hits (8.4 per 9 innings) in addition to 540 earned runs. The Guardians have compiled a team earned run average of 3.99 for the year (16th in baseball), and the staff has rung up 1,139 batters. They have walked 475 batters and their FIP is 4.17 as a squad for the year.

The Guardians have sent 456 relief pitchers to the hill so far this season. The relievers have inherited 180 runners so far this season with 33.3% of those players crossed the plate. They have compiled 39 saves this season and have blown 18 out of their 57 save opportunities. The Guardians bullpen have accumulated a save percentage of 68.4% and have come into the game in 152 save situations. The relievers have accumulated 92 holds on the year (4th in baseball). Guardians relief pitchers have come into the game with runners on base 128 times and also have had 159 appearances in high leverage situations.

The Cincinnati Reds have amassed 3,651 putouts on the campaign, in addition to 1,120 assists and 86 errors. Their fielding percentage is at .982 which is 27th in pro baseball, and have 102 double plays. The Guardians have turned 69.3% of balls hit into play into outs out of their 10,953 innings on the diamond, ranking them 19th in baseball.

Allen has thrown 356 frames and has tallied 303 punch outs during his career. Allen (22-23 career win-loss record) sits with a FIP of 4.50 while going up against 1,552 batters during his time in the major leagues. His earned run average is 4.57 (181 earned runs allowed) and his career WHIP is 1.465. He has surrendered 376 base hits (9.5 hits per 9 innings) and has had 146 walks.

Tampa Bay has tallied 157 HRs over the course of the season as well as 595 runs batted in. They have notched 210 two-baggers, while taking a walk 398 times as well as scoring 627 runs. The Tampa Bay Rays have a team on-base percentage of .313 as well as a team batting average of .251 on the season. The Rays have a slugging percentage of .403 and they score 4.54 runs per game (13th in MLB). They have struck out on 1,182 occasions (13th in the league) and have a total of 1,168 base knocks.

The Tampa Bay pitching staff have surrendered 571 runs so far this season while holding a team ERA of 3.89 (528 earned runs yielded). They have given up 181 dingers and they allow 4.21 runs per 9 innings (9th in baseball). The Rays have a team WHIP of 1.213 and have a FIP of 4.21 as a squad on the season. Their K/BB ratio comes in at 8.80 (1,194 strikeouts vs 396 free passes). They are currently ranked 6th in the league as a staff in total hits conceded with 1,086.

Tampa Bay bullpen pitchers hold an inherited score rate of 31.5% out of 143 inherited base runners. Their relievers have stepped onto the mound 131 times in high leverage situations and on 96 occasions with runners on. Sitting with 135 save situations, the Rays have tallied 78 holds and also 23 blown saves. They sit at 25th in MLB with a save rate of 58.2%, and they have sent 435 bullpen pitchers onto the field on the season. Tampa Bay has had bullpen pitchers step onto the hill in 55 save chances and they have earned 32 saves.

The Tampa Bay Rays have turned 127 double plays and have a fielding rate of .987 (10th in pro baseball). The Rays have accrued 1,215 assists, 64 errors and have earned 3,667 putouts on the campaign. Out of their 11,001 innings on the diamond, the Rays have accumulated a defensive efficiency of 70.9% (4th in baseball).

In his MLB career, Pepiot has conceded 282 base knocks while he has tallied 377 strikeouts in 366 frames. Pepiot (23-19 career mark) has earned a 3.47 earned run average and has allowed 6.9 hits per 9 innings. He has given up a total of 141 ER's while earning a WHIP of 1.139 and a FIP of 3.4. He has a strikeout to walk ratio of 2.79 and he has gone up against 1,494 opposing hitters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Tampa Bay (-132) and under 9 runs

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