Colorado Rockies vs Chicago Cubs Prediction, 5/27/2025 MLB Picks, Best Bets & Odds
Game: Colorado Rockies vs Chicago Cubs
Date: Tuesday, May 27, 2025
Location: Wrigley Field in Chicago, IL
TV: Marquee
Odds/Point Spread: Colorado (+120) Chicago (-144)
The Chicago Cubs (32-21) are hosting the Colorado Rockies (9-44) at Wrigley Field on Tuesday. The line on this contest has the Rockies at +120 while the Cubs are at -144. The total comes in at 8.5. The pitchers who are expected to start will be German Marquez and Cade Horton.


As a squad, the Colorado Rockies are knocking in 3.3 runs per contest, which ranks them 29th in MLB. They have earned a total of 172 runs scored while holding a team on-base percentage of .286. The Rockies have hit 84 doubles as a unit and have knocked 44 baseballs out of the park. They have earned 170 RBI's as well as 386 base knocks over the course of the season, while their team batting average is .220. Colorado has a slugging percentage of .361 and have been called out on strikes 521 times, while being walked on 150 occasions.
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Their strikeout to walk ratio is 1.85 and their pitching staff has a collective WHIP of 1.62. Rockies pitchers have allowed 65 home runs and 343 runs in total (30th in MLB). Colorado has yielded 558 base hits (10.9 per 9 innings) and also 293 earned runs. The Rockies have an ERA of 5.73 on the year (30th in baseball), and they have struck out 346 hitters. Their pitching staff has walked 187 opposing hitters and their FIP sits at 4.74 as a squad so far this season.
The Rockies relievers have recorded a save rate of 50.0% and have stepped onto the mound in 30 save situations. The bullpen pitchers have inherited 121 runners so far this season with 34.7% of those players earned a run for their team. Rockies pitchers have come into the game with opponents on base 66 times in addition to having 47 appearances in high leverage situations. The Rockies have dispatched 172 relief pitchers to the hill for the season. The relief pitchers have racked up 16 holds on the year (30th in the league). They have recorded 7 saves on the season and have blown 7 of 14 save opportunities.
The Rockies have converted 64.7% of baseballs in play into outs in their 4,140 innings on the field, which has them sitting 30th in the majors. The Cleveland Guardians have a tally of 1,380 putouts on the year, as well as 522 assists and 46 errors. Their fielding rate is holding at .976 which ranks 30th in baseball, and have accumulated 48 double plays.
Marquez has pitched in 1,067 frames and has accounted for 1,012 strikeouts in his pro baseball career. His earned run average is 4.56 (541 earned runs allowed) and his WHIP is 1.305. He has surrendered 1,068 hits (9.0 hits per nine innings) with 324 free passes. Marquez (66-63 mark in his career) has earned a FIP of 4.49 while he has gone up against 4,535 hitters in the major leagues.
The Chicago Cubs are sitting with a team on-base percentage of .337 as well as a team batting average of .264 so far this season. They have struck out on 421 occasions (19th in baseball) and have accounted for 492 base hits. Chicago has knocked in 78 home runs this year as well as 313 RBIs. The Cubs hold a slugging percentage of .459 and they are scoring 6.06 runs per contest (1st in the league). They have hit 102 doubles, while taking a walk 201 times as well as earning 321 runs.
The Chicago pitching staff have conceded 230 runs over the course of the season while holding a team ERA of 4.07 (214 earned runs surrendered). They have relinquished 61 home runs and they give up 4.37 runs per 9 innings (18th in baseball). The Cubs have a WHIP of 1.306 and have a FIP of 4.13 as a squad over the course of the season. They have earned a strikeout to walk ratio of 8.00 (421 strikeouts against 164 free passes). They come in at 22nd in the league as a staff in total hits given up with 454.
Chicago has had relief pitchers step onto the mound in 20 save chances and they have earned 12 saves. They are ranked 18th in the league with a save percentage of 60.0%, and they have sent 183 relievers onto the field this season. Their relievers have come in 54 times in high leverage situations and also on 40 occasions with runners on base. Chicago bullpen pitchers hold an inherited score rate of 35.7% of 56 inherited base runners. With 55 save situations, the Cubs have tallied 34 holds and also 8 blown saves.
Out of their 4,263 innings played, the Cubs hold a defensive efficiency of 69.6% (20th in baseball). The Chicago Cubs have gotten 45 double plays and own a fielding percentage of .986 (17th in baseball). The Cubs have recorded 445 assists, 27 errors and have accumulated 1,421 putouts for the year.
Horton (2-0 career win-loss mark) is the owner of a 4.47 ERA and has allowed 10.9 hits per 9 innings. His K/BB ratio is 3.33 and he has gone up against 63 opposing hitters in his career. He has conceded 7 earned runs while earning a WHIP of 1.418 and being the owner of a FIP of 4.4. During his pro baseball career, Horton has allowed 17 base hits while earning 10 strikeouts in 14 frames.
Who will win tonight's MLB game against the spread or moneyline?
Parlay's Pundit's Pick: Take Chicago (-144) and under 8.5 runs
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Additional Resources:
Chicago Cubs - Twitter
Colorado Rockies - Twitter