Colorado Rockies vs San Diego Padres Prediction, 9/12/2025 MLB Picks, Best Bets & Odds
Game: Colorado Rockies vs San Diego Padres
Date: Friday, September 12, 2025
Location: Petco Park in San Diego, CA
TV: Padres.TV
Odds/Point Spread: Colorado (+220) San Diego (-275)
The San Diego Padres (79-67) will try to beat the Colorado Rockies (40-106) at Petco Park on Friday. The moneyline on this matchup has Colorado at +220 while San Diego is priced at -275. The total is 8. The pitchers taking the mound are Tanner Gordon and Dylan Cease.


Colorado is slugging .390 and have been rung up 1,368 times, while drawing a walk on 366 occasions. They have 531 RBI's in addition to 1,168 hits so far this season, while their team batting average is sitting at .239. The Rockies have tallied 234 doubles as a team and have knocked 144 baseballs out of the stadium. They have tallied 545 runs scored while holding a team OBP of .296. As a team, the Colorado Rockies are knocking in 3.7 runs per contest, which has them sitting at 29th in the league.
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They have a strikeout to walk ratio of 1.94 and the pitching staff has recorded a WHIP of 1.60. Rockies pitchers have yielded 223 home runs in addition to 931 total runs (30th in MLB). Colorado has conceded 1,534 hits (10.9 per 9 innings) and 849 earned runs. The Rockies have compiled a team earned run average of 6.01 so far this year (30th in baseball), and their staff has rung up 976 hitters. They have walked 504 opposing players and their FIP is 5.22 as a team on the year.
Rockies bullpen pitchers have stepped onto the hill with runners on base 150 times and also have had 129 appearances in high leverage situations. The bullpen have accumulated 51 holds this season (30th in the league). The Rockies bullpen have earned a save rate of 52.0% and have entered the game in 101 save situations. They have 26 saves so far this season and have blown 24 of their 50 save opportunities. The bullpen pitchers have inherited 257 base runners so far this year and 36.2% of those runners ended up crossing the plate. The Rockies have sent 480 relievers to the mound for the year.
The Rockies have converted 65.7% of balls in play into outs out of 11,451 innings on the field, which has them sitting at 30th in pro baseball. The Cleveland Guardians have accumulated 3,817 putouts at this point in the season, as well as 1,348 assists and 103 errors. Their fielding percentage sits at .980 which ranks 30th in baseball, and have accumulated 142 double plays.
Gordon has taken the hill for 94 innings and has 72 punch outs in his career. His ERA is 7.36 (77 ER's allowed) and he has a career WHIP of 1.647. He has given up 134 base hits (12.8 hits per 9 innings) and has had 21 walks. Gordon (5-12 mark in his career) has a FIP of 7.25 while facing 432 hitters during his time in the major leagues.
The San Diego Padres have recorded an OBP of .321 as well as a batting average of .251 on the campaign. They have struck out on 1,037 occasions (28th in baseball) and are sitting with 1,226 base hits. San Diego has tallied 128 home runs this season and 580 RBIs. The Padres hold a slugging percentage of .386 and they have an average of 4.23 runs per outing (24th in the league). They have notched 238 doubles, while getting a free base 467 times and recording 617 runs.
The San Diego pitching staff have conceded 565 runs on the campaign and come in with a team ERA of 3.65 (523 earned runs surrendered). They have conceded 157 home runs and they concede 3.94 runs per 9 innings (3rd in baseball). The Padres hold a team WHIP of 1.210 in addition to having a FIP of 4.02 as a pitching staff so far this year. Their strikeout to walk ratio comes in at 8.80 (1,264 strikeouts against 481 bases on balls). They are currently ranked 1st in baseball as a staff in total hits relinquished with 1,080.
With 157 save situations, the Padres have compiled 92 holds and also 16 blown saves. San Diego has had relief pitchers enter the contest in 60 save chances and they have walked away with 44 saves. Their relievers have taken the field 195 times in high leverage situations and also on 166 occasions with base runners. San Diego relievers have an inherited score percentage of 28.8% out of 236 inherited runners. They sit at 1st in baseball holding a save percentage of 73.3%, and they have sent 517 relief pitchers onto the diamond so far this season.
The San Diego Padres have gotten 105 double plays and have a fielding percentage of .987 (13th in the majors). The Padres have 1,102 assists, 68 errors and have a total of 3,870 putouts so far this season. In their 11,610 innings played, the Padres hold a efficiency on defense of 71.8% (2nd in pro baseball).
So far in his career, Cease has allowed 839 hits while he has totaled 1,211 K's in 998 innings pitched. Cease (64-57 win-loss mark in his career) has earned a 3.90 ERA while giving up 7.6 hits per nine innings. He has conceded 432 earned runs while holding a WHIP of 1.265 and having a FIP of 3.8. He has a strikeout to walk ratio of 2.86 and he has faced 4,232 opposing batters so far in his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take San Diego (-275)
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Additional Resources:
San Diego Padres - Twitter
Colorado Rockies - Twitter