Detroit Tigers vs Cleveland Guardians Prediction, 10/1/2025 MLB Picks, Best Bets & Odds

Game: Detroit Tigers vs Cleveland Guardians

Date: Wednesday, October 1, 2025

Location: Progressive Field in Cleveland, OH

TV: ESPN

Odds/Point Spread: Detroit (+162) Cleveland (-196)

The Detroit Tigers (87-75) are en route to Progressive Field on Wednesday where they will go up against the Cleveland Guardians (88-74) in Game 2 of the AL Wild Card series. The odds on this game have Detroit at +162 while Cleveland is at -196. The total is set at 9. The starting pitchers are Casey Mize and Tanner Bibee.

Detroit has a slugging % of .413 and have been called out on strikes 1,454 times, while taking a walk on 511 occasions. They have accounted for 724 runs batted in and 1,346 base knocks for the season, while their team batting average is sitting at .247. The Tigers have hit 244 two-baggers as a squad and have hit 198 balls out of the park. They have notched a total of 758 runs scored and have an OBP of .316. As a squad, the Detroit Tigers are notching 4.7 runs per game, which ranks them 11th in MLB.

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They have earned a K/BB ratio of 2.84 and the pitching staff has earned a collective WHIP of 1.25. Tigers pitchers have conceded 187 home runs and 691 runs (16th in MLB). Detroit has conceded 1,309 base knocks (8.2 per 9 innings) as well as 630 earned runs. The Tigers are sitting with a team earned run average of 3.95 so far this season (16th in the league), and the staff has rung up 1,375 batters. Their pitching staff has walked 485 batters and their FIP comes in at 4.05 as a team for the year.

Tigers pitchers have entered the game with runners on 182 times as well as having 140 appearances in high leverage situations. The relief pitchers have racked up 75 holds so far this season (26th in the league). The Tigers relief pitchers have recorded a save rate of 64.5% and have come into the game in 142 save situations. They have compiled 40 saves this season and have blown 22 out of their 62 chances to save the game. The relief pitchers have inherited 258 runners for the year with 28.7% of them crossed the plate. The Tigers have sent 508 relievers to the hill on the year.

The Colorado Rockies have earned 4,309 putouts on the campaign, as well as 1,379 assists and 79 errors. Their fielding percentage is holding steady at .986 which has them ranked 14th in baseball, and have a total of 128 double plays. The Tigers have converted 70.2% of baseballs in play into outs out of their 12,927 innings on the diamond, which has them ranked 13th in pro baseball.

Mize (23-25 career record) is the owner of a FIP of 4.13 while he has gone up against 1,869 opposing batters in the major leagues. He has given up 446 base knocks (9.1 hits per 9 innings) and has 121 walks. His earned run average is 4.19 (205 earned runs allowed) and his career WHIP is 1.289. Mize has taken the hill for 440 innings and has racked up 365 strikeouts during his MLB career.

Cleveland has accounted for 168 HRs over the course of the season to go along with 621 runs batted in. They have put up 243 doubles, while taking a walk 494 times and notching 643 runs. The Cleveland Guardians have an on-base percentage of .296 as well as a team batting average of .226 so far this year. The Guardians have a team SLG% of .373 and they are scoring 3.97 runs per outing (28th in baseball). They have been rung up on 1,344 occasions (18th in the league) and have totaled 1,199 base knocks.

The Guardians have a WHIP of 1.261 and have a FIP of 3.95 as a pitching staff for the season. They sit at 11th in baseball as a staff in total hits given up with 1,291. The Cleveland pitching staff have allowed 649 runs so far this year while having an ERA of 3.70 (593 earned runs yielded). Their K/BB ratio comes in at 8.60 (1,381 strikeouts against 527 walks). They have allowed 169 homers and they surrender 4.05 runs per 9 innings (6th in the league).

Cleveland has called on relievers to enter the contest in 69 save opportunities and they have earned 47 saves. They sit at 6th in baseball with a save percentage of 68.1%, and they have sent 531 relievers onto the field on the season. Their relief pitchers have taken the field 192 times in high leverage situations and also on 151 occasions with runners on base. Cleveland bullpen pitchers have an inherited score percentage of 32.5% out of their 209 inherited runners. Sitting with 184 save situations, the Guardians have compiled 112 holds in addition to 22 blown saves.

Out of their 12,978 innings on the field, the Guardians have accumulated a defensive efficiency of 69.8% (17th in pro baseball). The Cleveland Guardians have gotten 121 double plays and own a fielding percentage of .983 (27th in professional baseball). The Guardians have 1,330 assists, 99 errors and have accumulated 4,326 putouts over the course of the season.

Bibee (34-23 career mark) has a 3.62 earned run average while giving up 8.0 hits per nine innings. His strikeout to walk ratio is 3.43 and he has faced 2,057 batters in his MLB career. He has allowed 200 ER's while holding a WHIP of 1.176 and a FIP of 3.6. During his career, Bibee has surrendered 442 hits while he has totaled 490 punch outs in 497 frames.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Detroit (+162)

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