Houston Astros vs Los Angeles Angels Prediction, 6/21/2025 MLB Picks, Best Bets & Odds

Game: Houston Astros vs Los Angeles Angels

Date: Saturday, June 21, 2025

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Houston (-130) Los Angeles (+110)

Angel Stadium is the site where the Los Angeles Angels (36-37) will attempt to defeat the Houston Astros (43-31) on Saturday. The moneyline on this contest has Houston at -130 and Los Angeles is coming in at +110. The over/under is 9. The pitchers taking the mound will be Brandon Walter and Jose Soriano.

The Astros have recorded 110 two-baggers as a unit and have hit 78 balls out of the stadium. Houston has a slugging % of .403 and have been called out on strikes 565 times, while being walked on 213 occasions. As a team, the Houston Astros are notching 4.3 runs per game, which is 15th in baseball. They have accumulated 303 RBI's as well as 641 hits on the season, while their batting average is at .259. They have notched a total of 317 runs while holding a team OBP of .323.

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They have accumulated a K/BB ratio of 3.20 and the pitching staff has a collective WHIP of 1.15. Astros pitchers have yielded 72 home runs and 263 runs in total (3rd in MLB). Houston has surrendered 523 base hits (7.2 per 9 innings) as well as 248 earned runs. The Astros have compiled a team ERA of 3.42 for the year (6th in the league), and the staff has rung up 723 hitters. Their pitching staff has walked 226 opposing hitters and their FIP comes in at 3.45 as a squad on the year.

The Astros have sent 227 relief pitchers to the mound so far this year. The relievers have inherited 78 runners so far this season with 29.5% of those players earned a run for their team. They have earned 20 saves for the season and have blown 7 of 27 save chances. The Astros bullpen have a save rate of 74.1% and have stepped onto the mound in 72 save situations. The bullpen have a total of 45 holds over the course of the season (14th in the league). Astros bullpen pitchers have gone to the mound with runners on 54 times and also have had 67 appearances in high leverage situations.

The Astros have transformed 71.2% of balls in play into outs in their 5,880 innings on the field, which has them sitting 6th in the majors. The Detroit Tigers have earned a total of 1,960 putouts this season, in addition to 557 assists and 33 errors. Their fielding percentage is currently at .987 which has them ranked 12th in the majors, and they have turned 48 double plays.

Walter has taken the hill for 40 frames and has earned 35 K's in his MLB career. Walter (0-0 win-loss mark in his career) sits with a FIP of 4.19 while he has faced 175 opposing batters in the major leagues. His ERA is 4.25 (19 earned runs allowed) and his WHIP is 1.368. He has given up 47 hits (10.5 hits per nine innings) with 8 free passes.

The Los Angeles Angels have compiled a team OBP of .288 as well as a batting average of .226 on the campaign. They have been rung up on 709 occasions (2nd in the league) and have recorded 548 base knocks. Los Angeles has accounted for 102 home runs for the season as well as 289 RBIs. The Angels have a slugging percentage of .398 and they are recording 4.11 runs per game (22nd in baseball). They have put up 96 doubles, while taking a walk 185 times and putting up 300 runs.

The Angels are sitting with a team WHIP of 1.465 in addition to having a FIP of 4.70 as a squad for the season. They rank 26th in MLB as a pitching staff in total hits allowed with 655. The Los Angeles pitching staff have allowed 356 runs so far this season while holding a team ERA of 4.63 (331 earned runs conceded). They currently have a strikeout to walk ratio of 7.80 (559 strikeouts against 287 free passes). They have conceded 95 home runs and they relinquish 4.98 runs per 9 innings (24th in baseball).

Los Angeles relief pitchers hold an inherited score percentage of 30.7% of 114 inherited base runners. Their bullpen pitchers have stepped onto the mound 92 times in high leverage situations in addition to 73 occasions with runners on. Sitting with 82 save situations, the Angels have 46 holds and also 13 blown saves. They are ranked 21st in MLB with a save percentage of 60.6%, and they have dispatched 241 relievers to the mound on the season. Los Angeles has called on relievers to step onto the hill in 33 save opportunities and they have converted 20 saves.

In their 5,790 innings played, the Angels hold a defensive efficiency of 68.1% (26th in professional baseball). The Los Angeles Angels have turned 84 double plays and hold a fielding percentage of .982 (28th in baseball). The Angels have racked up 652 assists, 48 errors and have a total of 1,930 putouts this year.

In his pro baseball career, Soriano has allowed 210 hits and he has 223 K's in 241 innings pitched. He has allowed a total of 94 earned runs while holding a WHIP of 1.319 and being the owner of a FIP of 3.5. His K/BB ratio is 2.06 and he has faced 1,022 opposing batters so far in his career. Soriano (11-15 mark in his career) has a 3.51 ERA and has given up 7.8 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Houston (-130)

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